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Immunology

D-Index
41
Citations
8042
World Ranking
4909
National Ranking
2191

Overview

Mansun Law is affiliated with the Scripps Research Institute in the United States and has a research focus predominantly in the field of Medicine with a specialization in Hepatology. Their work addresses significant topics including Hepatitis C virus research, Monoclonal and Polyclonal Antibodies research, Hepatitis B Virus studies, HIV research and treatment, Glycosylation and Glycoproteins research, T-cell and B-cell Immunology, and Blood groups and transfusion.

The scientist has contributed extensively to the understanding and development of therapeutic and vaccine strategies related to hepatitis viruses. Their recent publications include:

  • Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines, 2020, Science Advances
  • An alternate conformation of HCV E2 neutralizing face as an additional vaccine target, 2020, Science Advances
  • Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins, 2021, Immunity
  • An Antigenically Diverse, Representative Panel of Envelope Glycoproteins for Hepatitis C Virus Vaccine Development, 2021, Gastroenterology
  • Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies, 2023, Nature Communications

Mansun Law frequently publishes in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Science Advances
  • Journal of Hepatology
  • Hepatology

Their frequent co-authors include Erick Giang, Jens Bukh, Jannick Prentoe, Thomas R. Fuerst, and N. Tzarum, indicating active collaboration in advancing research within their specialty.

Their research spans multiple subfields, notably Hepatology, Radiology, Nuclear Medicine and Imaging, Epidemiology, Molecular Biology, and Virology. This interdisciplinary approach supports a broad perspective on viral pathogenesis and immune response mechanisms relevant to hepatitis viruses.

Best Publications

  • Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge

    Mansun Law;Toshiaki Maruyama;Jamie Lewis;Erick Giang

  • The formation and function of extracellular enveloped vaccinia virus.

    Geoffrey L. Smith;Alain Vanderplasschen;Mansun Law

  • Hepatitis C Virus E2 Envelope Glycoprotein Core Structure

    Leopold Kong;Erick Giang;Travis Nieusma;Rameshwar U. Kadam

  • A genetically humanized mouse model for hepatitis C virus infection

    Marcus Dorner;Joshua A. Horwitz;Justin B. Robbins;Walter T. Barry

  • Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus

    Erick Giang;Marcus Dorner;Jannick C. Prentoe;Marlène Dreux;Marlène Dreux

  • Vaccinia virus utilizes microtubules for movement to the cell surface

    Michael Hollinshead;Gaener Rodger;Henriette Van Eijl;Mansun Law

  • Completion of the entire hepatitis C virus life cycle in genetically humanized mice

    Marcus Dorner;Joshua A. Horwitz;Bridget M. Donovan;Rachael N. Labitt

  • Ultrastructural and Biophysical Characterization of Hepatitis C Virus Particles Produced in Cell Culture

    Pablo Gastaminza;Kelly A. Dryden;Bryan Boyd;Malcolm R. Wood

  • Entry of the vaccinia virus intracellular mature virion and its interactions with glycosaminoglycans.

    Gemma C. Carter;Mansun Law;Michael Hollinshead;Geoffrey L. Smith

  • Broadly neutralizing antibodies abrogate established hepatitis C virus infection

    Ype P. de Jong;Ype P. de Jong;Marcus Dorner;Michiel C. Mommersteeg;Jing W. Xiao

  • Molecular characterization of seven Chinese isolates of infectious bursal disease virus: classical, very virulent, and variant strains.

    Unknown

  • The exit of Vaccinia virus from infected cells

    Geoffrey L. Smith;Mansun Law

  • Ligand-induced and nonfusogenic dissolution of a viral membrane

    Mansun Law;Gemma C. Carter;Kim L. Roberts;Michael Hollinshead

  • Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1

    Leopold Kong;Erick Giang;Justin B. Robbins;Robyn L. Stanfield

  • Quantification of antibody responses against multiple antigens of the two infectious forms of Vaccinia virus provides a benchmark for smallpox vaccination.

    Mike M Pütz;Claire M Midgley;Mansun Law;Geoffrey L Smith

  • Vaccinia virus cores are transported on microtubules.

    Gemma C. Carter;Gaener Rodger;Gaener Rodger;Brendan J. Murphy;Mansun Law;Mansun Law

  • Vaccinia virus motility.

    Geoffrey L. Smith;Brendan J. Murphy;Mansun Law

  • Antibody neutralization of the extracellular enveloped form of vaccinia virus.

    Mansun Law;Geoffrey L. Smith

  • Antibody-sensitive and antibody-resistant cell-to-cell spread by vaccinia virus: role of the A33R protein in antibody-resistant spread

    Mansun Law;Ruth Hollinshead;Geoffrey L. Smith

  • VH1-69 antiviral broadly neutralizing antibodies: genetics, structures, and relevance to rational vaccine design.

    Fang Chen;Netanel Tzarum;Ian A Wilson;Mansun Law

  • Comparing Antigenicity and Immunogenicity of Engineered gp120

    Suganya Selvarajah;Bridget Puffer;Ralph Pantophlet;Mansun Law

  • Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy

    Mansun Law;Rosa M. F. Cardoso;Ian A. Wilson;Dennis R. Burton

Frequent Co-Authors

Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Geoffrey L. Smith
Geoffrey L. Smith University of Oxford
Ian A. Wilson
Ian A. Wilson Scripps Research Institute
Jens Bukh
Jens Bukh University of Copenhagen
Michael Hollinshead
Michael Hollinshead University of Cambridge
Robyn L. Stanfield
Robyn L. Stanfield Scripps Research Institute
Steven K. H. Foung
Steven K. H. Foung Stanford University
Alexander Ploss
Alexander Ploss Princeton University
Jonathan K. Ball
Jonathan K. Ball University of Nottingham
Andrew B. Ward
Andrew B. Ward Scripps Research Institute

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