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Giovanni Scapagnini

Giovanni Scapagnini

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
14305
World Ranking
9198
National Ranking
253

Overview

Giovanni Scapagnini is affiliated with the University of Molise in Italy and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research primarily addresses physiological and molecular biological processes, with a particular focus on nutrition, dietetics, biochemistry, and public health.

The scientist's research spans several specialized subfields, including physiology, molecular biology, nutrition and dietetics, biochemistry, and occupational health. Their work frequently explores key topics such as antioxidant activity and oxidative stress, fatty acid research and health, genomics related to phytochemicals and oxidative stress, sirtuins and resveratrol in medicine, nutritional studies and diet, telomeres, telomerase and senescence, as well as genetics, aging, and longevity in model organisms.

Scapagnini's publication record features work in various scientific journals, with notable frequent venues being:

  • Nutrients
  • Pharmaceuticals
  • Molecules
  • Marine Drugs
  • Antioxidants

Highlighted recent publications include:

  • "Cocoa Polyphenols and Gut Microbiota Interplay: Bioavailability, Prebiotic Effect, and Impact on Human Health," 2020, Nutrients
  • "Polyphenols as Caloric Restriction Mimetics Regulating Mitochondrial Biogenesis and Mitophagy," 2020, Trends in Endocrinology and Metabolism
  • "Caloric Restriction Mimetics in Nutrition and Clinical Trials," 2021, Frontiers in Nutrition
  • "Astaxanthin as a Modulator of Nrf2, NF-κB, and Their Crosstalk: Molecular Mechanisms and Possible Clinical Applications," 2022, Molecules
  • "Spirulina Microalgae and Brain Health: A Scoping Review of Experimental and Clinical Evidence," 2021, Marine Drugs

Frequent collaborative partners include:

  • Sergio Davinelli
  • Alessandro Medoro
  • Sawan Alì
  • Mariano Intrieri
  • Graziamaria Corbi

Giovanni Scapagnini's research addresses significant intersections between molecular biology, nutrition, and clinical applications, contributing to understanding the mechanisms underlying aging, nutritional interventions, and oxidative stress. Their work with polyphenols, caloric restriction mimetics, and antioxidants highlights an ongoing interest in the molecular pathways that influence healthspan and disease prevention.

Best Publications

  • Nutritional approaches to combat oxidative stress in Alzheimer's disease.

    D.Allan Butterfield;Alessandra Castegna;Chava B. Pocernich;Jennifer Drake

  • Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia

    Vittorio Calabrese;Raffaele Lodi;Caterina Tonon;Velia D'Agata

  • Modulation of Nrf2/ARE Pathway by Food Polyphenols: A Nutritional Neuroprotective Strategy for Cognitive and Neurodegenerative Disorders

    Giovanni Scapagnini;Vasto Sonya;Abraham G. Nader;Caruso Calogero

  • New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates—Nrf2 activators and GSK-3 inhibitors

    Michael Maes;Zdenĕk Fišar;Miguel Medina;Giovanni Scapagnini

  • Caffeic Acid Phenethyl Ester and Curcumin: A Novel Class of Heme Oxygenase-1 Inducers

    G. Scapagnini;R. Foresti;V. Calabrese;A. M. Giuffrida Stella

  • Free radicals and brain aging.

    H.Fai Poon;Vittorio Calabrese;Giovanni Scapagnini;D.Allan Butterfield

  • Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review.

    Sergio Davinelli;Michael E Nielsen;Giovanni Scapagnini

  • Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders.

    Cesare Mancuso;Giovanni Scapagini;Diego Currò;Anna Maria Giuffrida Stella

  • Mitochondrial involvement in brain function and dysfunction: relevance to aging, neurodegenerative disorders and longevity.

    V. Calabrese;G. Scapagnini;A. M. Giuffrida Stella;T. E. Bates

  • Free Radicals: Key to Brain Aging and Heme Oxygenase as a Cellular Response to Oxidative Stress

    H. Fai Poon;Vittorio Calabrese;Giovanni Scapagnini;D. Allan Butterfield

  • Healthy aging diets other than the Mediterranean: A focus on the Okinawan diet

    Donald Craig Willcox;Donald Craig Willcox;Donald Craig Willcox;Giovanni Scapagnini;Bradley J. Willcox

  • Nitrosative Stress, Cellular Stress Response, and Thiol Homeostasis in Patients with Alzheimer's Disease

    Vittorio Calabrese;Rukhsana Sultana;Giovanni Scapagnini;Eleonora Guagliano

  • Vitamin E and Neurodegenerative Disorders Associated with Oxidative Stress

    D. Allan Butterfield;Alessandra Castegna;Jennifer Drake;Giovanni Scapagnini

  • Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: a nutritional approach

    V. Calabrese;G. Scapagnini;C. Colombrita;A. Ravagna

  • Nitric oxide synthase is present in the cerebrospinal fluid of patients with active multiple sclerosis and is associated with increases in cerebrospinal fluid protein nitrotyrosine and S-nitrosothiols and with changes in glutathione levels.

    Vittorio Calabrese;Giovanni Scapagnini;Agrippino Ravagna;Rita Bella

  • Curcumin activates defensive genes and protects neurons against oxidative stress.

    Giovanni Scapagnini;Giovanni Scapagnini;Claudia Colombrita;Claudia Colombrita;Marialaura Amadio;Velia D'Agata;Velia D'Agata

  • Nitric oxide and cellular stress response in brain aging and neurodegenerative disorders: the role of vitagenes.

    Vittorio Calabrese;Debra Boyd-Kimball;Giovanni Scapagnini;D Allan Butterfield

  • Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress

    Giovanni Scapagnini;D. Allan Butterfield;Claudia Colombrita;Claudia Colombrita;Rukhsana Sultana

  • Antioxidants as antidepressants: fact or fiction?

    Giovanni Scapagnini;Sergio Davinelli;Filippo Drago;Antonino De Lorenzo

  • Probiotics and Oral Health

    Bernard Bizzini;Giuseppe Pizzo;Giovanni Scapagnini;Domenico Nuzzo

Frequent Co-Authors

Vittorio Calabrese
Vittorio Calabrese University of Catania
Calogero Caruso
Calogero Caruso University of Palermo
D. Allan Butterfield
D. Allan Butterfield University of Kentucky
Alessandro Quattrone
Alessandro Quattrone University of Trento
Giuseppina Candore
Giuseppina Candore University of Palermo
Stefano Govoni
Stefano Govoni University of Pavia
Daniel L. Alkon
Daniel L. Alkon West Virginia University
Immaculata De Vivo
Immaculata De Vivo Harvard University
Giovanni Li Volti
Giovanni Li Volti University of Catania
Filippo Drago
Filippo Drago University of Catania

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