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Medicine

D-Index
76
Citations
21877
World Ranking
18760
National Ranking
9346

Overview

Wael Sakr is affiliated with Wayne State University in the United States. Their research spans multiple areas within Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on molecular-level processes and clinical oncology. Sakr has made contributions across various subfields including Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, Otorhinolaryngology, and Surgery.

Their work covers several main topics, specifically:

  • Head and Neck Cancer Studies
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Lung Cancer Research Studies
  • Renal cell carcinoma treatment
  • Renal and related cancers
  • Medical Imaging and Pathology Studies
  • Autophagy in Disease and Therapy

Recent scientific publications include the following papers:

  • Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized Intergroup study 0099, 2023, Journal of Clinical Oncology
  • Recurrent KRAS mutations are early events in the development of papillary renal neoplasm with reverse polarity, 2022, Modern Pathology
  • p62/SQSTM1-induced caspase-8 aggresomes are essential for ionizing radiation-mediated apoptosis, 2021, Cell Death and Disease
  • The vulnerable primed cancer stem cells in disguise: demystifying the role of Maspin, 2022, Cancer and Metastasis Reviews

Sakr's frequent publication venues demonstrate a diverse engagement with journals focused on oncology, pathology, cellular biology, and cancer metastasis:

  • Journal of Clinical Oncology
  • Modern Pathology
  • Cell Death and Disease
  • Cancer and Metastasis Reviews

Collaborations have been established with several co-authors, including:

  • Muhyi Al-Sarraf
  • Michael LeBlanc
  • Padmini Giri
  • K.K. Fu
  • Jay S. Cooper

Best Publications

  • Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized Intergroup study 0099.

    M Al-Sarraf;M LeBlanc;P G Giri;K K Fu

  • The Frequency of Carcinoma and Intraepithelial Neoplasia of the Prostate in Young Male Patients

    W.A. Sakr;G.P. Haas;B.F. Cassin;J.E. Pontes

  • High grade prostatic intraepithelial neoplasia (HGPIN) and prostatic adenocarcinoma between the ages of 20-69: an autopsy study of 249 cases.

    W. A. Sakr;D. J. Grignon;J. D. Crissman;L. K. Heilbrun

  • Phase II randomized clinical trial of lycopene supplementation before radical prostatectomy

    Omer Kucuk;Fazlul H. Sarkar;Wael Sakr;Zora Djuric

  • Treatment and Prevention of Intraepithelial Neoplasia: An Important Target for Accelerated New Agent Development: Recommendations of the American Association for Cancer Research Task Force on the Treatment and Prevention of Intraepithelial Neoplasia

    Joyce A. O’Shaughnessy;Gary J. Kelloff;Gary B. Gordon;Andrew J. Dannenberg

  • Interobserver reproducibility of Gleason grading of prostatic carcinoma: Urologic pathologists

    William C. Allsbrook;William C. Allsbrook;Kathy A. Mangold;Kathy A. Mangold;Maribeth H. Johnson;Maribeth H. Johnson;Roger B. Lane;Roger B. Lane

  • Evidence supports a faster growth rate and/or earlier transformation to clinically significant prostate cancer in black than in white American men, and influences racial progression and mortality disparity.

    Isaac J. Powell;Cathryn H. Bock;Julie J. Ruterbusch;Wael Sakr

  • Age and racial distribution of prostatic intraepithelial neoplasia.

    W A Sakr;D J Grignon;G P Haas;L K Heilbrun

  • Prognostic factors and reporting of prostate carcinoma in radical prostatectomy and pelvic lymphadenectomy specimens.

    Jonathan I. Epstein;Mahul Amin;Liliane Boccon-Gibod;Lars Egevad

  • Epidemiology of prostate cancer.

    Gabriel P. Haas;Wael A. Sakr

  • LIMITED ROLE OF RADIONUCLIDE BONE SCINTIGRAPHY IN PATIENTS WITH PROSTATE SPECIFIC ANTIGEN ELEVATIONS AFTER RADICAL PROSTATECTOMY

    Michael L. Cher;Fernando J. Jr Bianco;John S. Lam;Lawrence P. Davis

  • Loss of Heterozygosity of the BRCA1 and Other Loci on Chromosome 17q in Human Prostate Cancer

    Xiang Gao;Alex Zacharek;Alicia Salkowski;David J. Grignon

  • Pathogenesis of invasive micropapillary carcinoma: role of MUC1 glycoprotein.

    Hind Nassar;Vishali Pansare;Hongquan Zhang;Minxing Che

  • High Levels of Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Expression Are Associated with Poor Outcome in Invasive Bladder Cancer

    David J. Grignon;Wael Sakr;Marta Toth;Vincent Ravery

  • Her-2/neu overexpression in muscle-invasive urothelial carcinoma of the bladder : Prognostic significance and comparative analysis in primary and metastatic tumors

    Rafael E. Jimenez;Maha Hussain;Fernando J. Bianco;Ulka Vaishampayan

  • Effects of Lycopene Supplementation in Patients with Localized Prostate Cancer

    Omer Kucuk;Fazlul H. Sarkar;Zora Djuric;Wael Sakr

  • Elevated 12-lipoxygenase mRNA expression correlates with advanced stage and poor differentiation of human prostate cancer

    Xiang Gao;David J. Grignon;Taibi Chbihi;Alex Zacharek

  • Allelic Loss in Locally Metastatic, Multisampled Prostate Cancer

    W A Sakr;J A Macoska;P Benson;D J Grignon

  • Loss of Let-7 Up-Regulates EZH2 in Prostate Cancer Consistent with the Acquisition of Cancer Stem Cell Signatures That Are Attenuated by BR-DIM

    Dejuan Kong;Elisabeth Heath;Wei Chen;Michael L. Cher

  • Evidence for Three Tumor Suppressor Gene Loci on Chromosome 8p in Human Prostate Cancer

    Jill A. Macoska;Tanya M. Trybus;Philip D. Benson;Wael A. Sakr

Frequent Co-Authors

David J. Grignon
David J. Grignon Indiana University
David P. Wood
David P. Wood University of Michigan–Ann Arbor
Fazlul H. Sarkar
Fazlul H. Sarkar Wayne State University
Ian M. Thompson
Ian M. Thompson The University of Texas Health Science Center at San Antonio
Maha Hussain
Maha Hussain Northwestern University
Yong Q. Chen
Yong Q. Chen Jiangnan University
E. David Crawford
E. David Crawford University of California, San Diego
Rodolfo Montironi
Rodolfo Montironi Marche Polytechnic University
Kenneth V. Honn
Kenneth V. Honn Wayne State University
Jonathan I. Epstein
Jonathan I. Epstein Johns Hopkins University

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