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Medicine

D-Index
80
Citations
24430
World Ranking
17073
National Ranking
8555

Overview

Timothy J. McDonnell is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily falls within the field of Medicine, with a strong focus on subfields such as Pathology and Forensic Medicine, Oncology, Genetics, Molecular Biology, and Hematology.

The scientist's work concentrates on key topics including:

  • Lymphoma Diagnosis and Treatment
  • Chronic Lymphocytic Leukemia Research
  • CAR-T cell therapy research
  • Viral-associated cancers and disorders
  • Cancer Genomics and Diagnostics
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Emergency and Acute Care Studies

Timothy J. McDonnell has contributed to several recent papers, which include:

  • Smart Start: Rituximab, Lenalidomide, and Ibrutinib in Patients With Newly Diagnosed Large B-Cell Lymphoma, 2022, Journal of Clinical Oncology
  • Pure erythroid leukemia is characterized by biallelic TP53 inactivation and abnormal p53 expression patterns in de novo and secondary cases, 2022, Haematologica
  • The Lymphoma Epidemiology of Outcomes cohort study: Design, baseline characteristics, and early outcomes, 2024, American Journal of Hematology
  • MYC rearrangement and MYC/BCL2 double expression but not cell-of-origin predict prognosis in R-CHOP treated diffuse large B-cell lymphoma, 2020, European Journal Of Haematology
  • High-grade B-cell lymphoma (HGBL)-NOS is clinicopathologically and genetically more similar to DLBCL/HGBL-DH than DLBCL, 2022, Leukemia

Their frequent co-authors include:

  • Christopher R. Flowers
  • Loretta J. Nastoupil
  • Matthew J. Maurer
  • James R. Cerhan
  • Brad S. Kahl

Timothy J. McDonnell often publishes in these venues:

  • Blood
  • American Journal of Hematology
  • Blood Advances
  • Journal of Clinical Oncology
  • Haematologica

Best Publications

  • bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation.

    Timothy J. McDonnell;Natasha Deane;Frances M. Platt;Gabriel Nunez

  • Expression of the Protooncogene bcl-2 in the Prostate and Its Association with Emergence of Androgen-independent Prostate Cancer

    Timothy J. McDonnell;Patricia Troncoso;Shawn M. Brisbay;Christopher Logothetis

  • Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14; 18).

    Timothy J. McDonnell;Stanley J. Korsmeyer

  • mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

    Pradip K Majumder;Phillip G Febbo;Phillip G Febbo;Rachel Bikoff;Rachel Bikoff;Raanan Berger;Raanan Berger

  • Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer.

    J. A. Roth;D. Nguyen;D. D. Lawrence;B. L. Kemp

  • A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

    Juan Fueyo;Candelaria Gomez-Manzano;Ramon Alemany;Polly S.Y. Lee

  • Overexpression of ErbB2 Blocks Taxol-Induced Apoptosis by Upregulation of p21Cip1, which Inhibits p34Cdc2 Kinase

    Dihua Yu;Tong Jing;Bolin Liu;Jun Yao

  • Regulation of Akt/PKB Activity, Cellular Growth, and Apoptosis in Prostate Carcinoma Cells by MMAC/PTEN

    Michael A. Davies;Dimpy Koul;Haninder Dhesi;Russell Berman

  • Bcl-2 expression in chronic lymphocytic leukemia and its correlation with the induction of apoptosis and clinical outcome

    L. E. Robertson;W. Plunkett;K. McConnell;M. J. Keating

  • Bcl-2 expression causes redistribution of glutathione to the nucleus

    D. W. Voehringer;D. J. McConkey;T. J. McDonnell;S. Brisbay

  • Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy.

    Stephen G Swisher;Jack A Roth;Ritsuko Komaki;Jian Gu

  • Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis.

    Candelaria Gomez-Manzano;Juan Fueyo;Athanassios P. Kyritsis;Peter A. Steck

  • Deregulated Bcl-2-immunoglobulin transgene expands a resting but responsive immunoglobulin M and D-expressing B-cell population.

    Timothy J. McDonnell;Gabriel Nunez;Frances M. Platt;David Hockenberry

  • Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.

    Rebecca L.H. Bigelow;Nikhil S. Chari;Anne Birgitte Undén;Kevin B. Spurgers

  • Regulation of the Proto-oncogenes bcl-2 and c-myc by the Wilms' Tumor Suppressor Gene WT1

    Stephen M. Hewitt;Shinshichi Hamada;Timothy J. McDonnell;Frank J. Rauscher

  • Calcitriol-induced apoptosis in LNCaP cells is blocked by overexpression of Bcl-2.

    Sarah E. Blutt;Timothy J. Mcdonnell;Tara C. Polek;Nancy L. Weigel

  • Bcl-2 maintains B cell memory

    Gabriel Nuñez;David Hockenbery;Timothy J. McDonnell;Craig M. Sorensen

  • Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols

    Nena Mirkovic;David W. Voehringer;Michael D. Story;David J. McConkey

  • Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck.

    Ta Jen Liu;Adel K. El-Naggar;Timothy J. McDonnell;Kim D. Steck

  • Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma.

    Hesham M Amin;Timothy J McDonnell;Yupo Ma;Quan Lin

Frequent Co-Authors

L. Jeffrey Medeiros
L. Jeffrey Medeiros The University of Texas MD Anderson Cancer Center
Raymond E. Meyn
Raymond E. Meyn The University of Texas MD Anderson Cancer Center
Jack A. Roth
Jack A. Roth The University of Texas MD Anderson Cancer Center
Luis Fayad
Luis Fayad The University of Texas MD Anderson Cancer Center
Raymond Lai
Raymond Lai University of Alberta
Carlos E. Bueso-Ramos
Carlos E. Bueso-Ramos The University of Texas MD Anderson Cancer Center
Patricia Troncoso
Patricia Troncoso The University of Texas MD Anderson Cancer Center
Fredrick B. Hagemeister
Fredrick B. Hagemeister The University of Texas MD Anderson Cancer Center
Louis L. Pisters
Louis L. Pisters The University of Texas MD Anderson Cancer Center
Kim Anh Do
Kim Anh Do The University of Texas MD Anderson Cancer Center

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