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Immunology

D-Index
50
Citations
11243
World Ranking
4213
National Ranking
200

Overview

Thierry Defrance is affiliated with Claude Bernard University Lyon 1 in France. Their research lies predominantly in the fields of Medicine and Immunology and Microbiology. The main subfields covered include Immunology, Infectious Diseases, Epidemiology, Molecular Biology, and Genetics.

Their work encompasses multiple main topics, notably SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, Immune Cell Function and Interaction, Influenza Virus Research Studies, and the COVID-19 Impact on Reproduction.

Among the recent published papers by Thierry Defrance are:

  • Immunogenicity and efficacy of heterologous ChAdOx1-BNT162b2 vaccination, 2021, Nature
  • Infection or a third dose of mRNA vaccine elicits neutralizing antibody responses against SARS-CoV-2 in kidney transplant recipients, 2022, Science Translational Medicine
  • αvβ8 integrin-expression by BATF3-dependent dendritic cells facilitates early IgA responses to Rotavirus, 2020, Mucosal Immunology
  • Prior SARS-CoV-2 infection enhances and reshapes spike protein-specific memory induced by vaccination, 2023, Science Translational Medicine
  • Inverted direct allorecognition triggers early donor-specific antibody responses after transplantation, 2022, Science Translational Medicine

Frequent co-authors working with Thierry Defrance include Olivier Thaunat, Véronique Barateau, Emmanuel Morélon, Sophia Djebali, and Thierry Walzer. Their collaboration counts range from 4 to 9 joint publications.

The prominent publication venues featuring Thierry Defrance's work are Science Translational Medicine with 3 publications, bioRxiv (Cold Spring Harbor Laboratory) with 2, and single publications in Nature, Mucosal Immunology, and The Journal of Immunology.

Best Publications

  • Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes.

    Francoise Rousset;Eric Garcia;Thierry Defrance;Catherine Peronne

  • Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A.

    T Defrance;B Vanbervliet;F Brière;I Durand

  • Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities.

    T Yokota;T Otsuka;T Mosmann;J Banchereau

  • Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes.

    T Defrance;J P Aubry;F Rousset;B Vanbervliet

  • Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway

    Catherine Kern;Jean-François Cornuel;Christian Billard;Ruoping Tang

  • TLR agonists selectively promote terminal plasma cell differentiation of B cell subsets specialized in thymus-independent responses.

    Laurent Genestier;Morgan Taillardet;Morgan Taillardet;Paul Mondiere;Paul Mondiere;Hanane Gheit;Hanane Gheit

  • Interleukin 13 is a B cell stimulating factor.

    T Defrance;P Carayon;G Billian;J C Guillemot

  • Activation of human B lymphocytes through CD40 and interleukin 4.

    A Vallé;C E Zuber;T Defrance;O Djossou

  • B cell growth-promoting activity of recombinant human interleukin 4.

    T Defrance;B Vanbervliet;J P Aubry;Y Takebe

  • Modulation and functional involvement of CB2 peripheral cannabinoid receptors during B-cell differentiation

    Pierre Carayon;Jean Marchand;Danielle Dussossoy;Jean-Marie Derocq

  • Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination.

    Bruno Pozzetto;Vincent Legros;Vincent Legros;Sophia Djebali;Véronique Barateau

  • Responsiveness of chronic lymphocytic leukemia B cells activated via surface Igs or CD40 to B-cell tropic factors.

    AC Fluckiger;JF Rossi;A Bussel;P Bryon

  • Triggering of CD40 Antigen Inhibits Fludarabine-Induced Apoptosis in B Chronic Lymphocytic Leukemia Cells

    Maria Fiammetta Romano;Annalisa Lamberti;Pierfrancesco Tassone;Fiorella Alfinito

  • Regulation of Fc receptor for IgE (CD23) and class II MHC antigen expression on Burkitt's lymphoma cell lines by human IL-4 and IFN-gamma.

    F Rousset;R W Malefijt;B Slierendregt;J P Aubry

  • FLICE-inhibitory protein is a key regulator of germinal center B cell apoptosis.

    Ana Hennino;Marion Bérard;Peter H. Krammer;Thierry Defrance

  • Regulation of germinal center B cell differentiation. Role of the human APO-1/Fas (CD95) molecule.

    Chantal Lagresle;Chantal Bella;Peter T. Daniel;Peter H. Krammer

  • Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis.

    C Lagresle;P Mondière;C Bella;P H Krammer

  • Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants.

    Alice Koenig;Alice Koenig;Chien-Chia Chen;Antoine Marçais;Thomas Barba;Thomas Barba

  • The TLR1/2 agonist PAM(3)CSK(4) instructs commitment of human hematopoietic stem cells to a myeloid cell fate.

    K. De Luca;V. Frances-Duvert;V. Frances-Duvert;M.-J. Asensio;M.-J. Asensio;R. Ihsani;R. Ihsani

  • Interleukin 4 counteracts the interleukin 2-induced proliferation of monoclonal B cells.

    S Karray;T DeFrance;H Merle-Béral;J Banchereau

  • Human recombinant IL-4 induces activated B lymphocytes to produce IgG and IgM.

    T Defrance;B Vanbervliet;J Pène;J Banchereau

Frequent Co-Authors

Gilles Salles
Gilles Salles Memorial Sloan Kettering Cancer Center
Peter H. Krammer
Peter H. Krammer German Cancer Research Center
Philippe Gaulard
Philippe Gaulard Université Paris Cité
Olivier Hermine
Olivier Hermine Necker-Enfants Malades Hospital
Els Verhoeyen
Els Verhoeyen Inserm : Institut national de la santé et de la recherche médicale
Patrice N. Marche
Patrice N. Marche Grenoble Alpes University
Ken-ichi Arai
Ken-ichi Arai University of Tokyo
Mitchell Kronenberg
Mitchell Kronenberg University of California, San Diego
Bruno Lina
Bruno Lina Claude Bernard University Lyon 1

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