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Simone M. Schoenwaelder

Simone M. Schoenwaelder

D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
9391
World Ranking
18338
National Ranking
537

Overview

Simone M. Schoenwaelder is affiliated with The Heart Research Institute in Australia. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several subfields including Hematology, Pulmonary and Respiratory Medicine, Cardiology and Cardiovascular Medicine, Immunology, and Molecular Biology.

Their work addresses key topics within platelet biology and cardiovascular health. Main research interests include:

  • Platelet Disorders and Treatments
  • Blood properties and coagulation
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cell Adhesion Molecules Research
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Acute Ischemic Stroke Management
  • COVID-19 Clinical Research Studies

Recent scholarly publications by Simone M. Schoenwaelder showcase a range of studies on platelet function, thrombolysis, and stroke models. Selected recent papers include:

  • "Microfluidic post method for 3-dimensional modeling of platelet-leukocyte interactions," 2022, The Analyst
  • "GPIbα-filamin A interaction regulates megakaryocyte localization and budding during platelet biogenesis," 2023, Blood
  • "Agitation-dependent biomechanical forces modulate GPVI receptor expression and platelet adhesion capacity during storage," 2022, Thrombosis Journal
  • "Improving treatment for acute ischemic stroke-Clot busting innovation in the pipeline," 2022, Frontiers in Medical Technology
  • "Development of a carotid artery thrombolysis stroke model in mice," 2022, Blood Advances

Frequent collaborators in their research include Shaun P. Jackson, Imala Alwis, Rhyll E. Smythe, Jessica MacLean, and Yuping Yuan. Their publications appear in multiple scientific journals, notably:

  • Thrombosis Journal
  • UNC Libraries
  • The Analyst
  • Blood
  • Frontiers in Medical Technology

Best Publications

  • Bidirectional signaling between the cytoskeleton and integrins.

    Simone M Schoenwaelder;Keith Burridge

  • PI 3-kinase p110β: a new target for antithrombotic therapy

    Shaun P Jackson;Simone Marianne Schoenwaelder;Isaac Goncalves;Warwick Scott Nesbitt

  • Thromboinflammation: challenges of therapeutically targeting coagulation and other host defense mechanisms

    Shaun P. Jackson;Shaun P. Jackson;Shaun P. Jackson;Roxane Darbousset;Roxane Darbousset;Simone M. Schoenwaelder;Simone M. Schoenwaelder

  • Correction: Corrigendum: 14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function

    Simone M. Schoenwaelder;Roxane Darbousset;Susan L. Cranmer;Hayley S. Ramshaw

  • Rap1b is required for normal platelet function and hemostasis in mice

    Magdalena Chrzanowska-Wodnicka;Susan S Smyth;Simone Marianne Schoenwaelder;Thomas H Fischer

  • Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function

    Simone Marianne Schoenwaelder;Yu-Ping Yuan;Emma C Josefsson;Michael J White

  • Bcl-xL inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets

    Simone M. Schoenwaelder;Kate E. Jarman;Elizabeth E. Gardiner;My Hua

  • Antiplatelet therapy: in search of the 'magic bullet'.

    Shaun P. Jackson;Simone M. Schoenwaelder

  • Reconstituted high-density lipoprotein attenuates platelet function in individuals with type 2 diabetes mellitus by promoting cholesterol efflux.

    Anna Calkin;Brian G Drew;Akiko Ono;Stephen J Duffy

  • Focal adhesion kinase (pp125FAK) cleavage and regulation by calpain

    Prasad Cooray;Yuping Yuan;Simone M Schoenwaelder;Christina A Mitchell

  • Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling.

    Isobel D Lawrenson;Sabine Hildegard Wimmer-Kleikamp;Peter Lock;Simone Marianne Schoenwaelder

  • The protein tyrosine phosphatase Shp-2 regulates RhoA activity.

    Simone M. Schoenwaelder;Leslie A. Petch;David Williamson;Randy Shen

  • Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRγ deficiency

    Pierre Mangin;Pierre Mangin;Pierre Mangin;Cindy Li Shen Yap;Cindy Li Shen Yap;Cindy Li Shen Yap;C Nonne;C Nonne;C Nonne;Sharelle Anne Sturgeon;Sharelle Anne Sturgeon;Sharelle Anne Sturgeon

  • Procoagulant platelets: are they necrotic?

    Shaun P. Jackson;Simone M. Schoenwaelder

  • Adhesion receptor activation of phosphatidylinositol 3-kinase. von Willebrand factor stimulates the cytoskeletal association and activation of phosphatidylinositol 3-kinase and pp60c-src in human platelets.

    Shaun P. Jackson;Simone M. Schoenwaelder;Yuping Yuan;Ian Rabinowitz

  • Calpain Cleavage of Focal Adhesion Proteins Regulates the Cytoskeletal Attachment of Integrin αIIbβ3 (Platelet Glycoprotein IIb/IIIa) and the Cellular Retraction of Fibrin Clots

    Simone M Schoenwaelder;Yuping Yuan;Prasad Cooray;Hatem Hh Salem

  • The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi.

    Mehran Ghasemzadeh;Zane Kaplan;Imala Alwis;Simone Marianne Schoenwaelder

  • Evidence for a Calpeptin-sensitive Protein-tyrosine Phosphatase Upstream of the Small GTPase Rho A NOVEL ROLE FOR THE CALPAIN INHIBITOR CALPEPTIN IN THE INHIBITION OF PROTEIN-TYROSINE PHOSPHATASES

    Simone M. Schoenwaelder;Keith Burridge

  • Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth

    Akiko Ono;Erik Westein;Sarah Tzu-Feng Hsiao;Warwick Scott Nesbitt

  • The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function

    Jessica Kate Mountford;Claire Petitjean;Harun Wijanarko Kusuma Putra;Jonathan Alexander McCafferty

Frequent Co-Authors

Shaun P. Jackson
Shaun P. Jackson University of Sydney
Benjamin T. Kile
Benjamin T. Kile University of Adelaide
David C. S. Huang
David C. S. Huang Walter and Eliza Hall Institute of Medical Research
Elizabeth E. Gardiner
Elizabeth E. Gardiner Australian National University
Christina Anne Mitchell
Christina Anne Mitchell Monash University
Olivier Delattre
Olivier Delattre PSL University
Andrew W. Roberts
Andrew W. Roberts Walter and Eliza Hall Institute of Medical Research
Alexandre Arcaro
Alexandre Arcaro University of Bern
Keith Burridge
Keith Burridge University of North Carolina at Chapel Hill
Cheng Zhu
Cheng Zhu Georgia Institute of Technology

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