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Richard Breathnach

Richard Breathnach

Inserm : Institut national de la santé et de la recherche médicale
France

Research.com Recognitions

Awards & Achievements

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

Gene
DNA
Enzyme

His scientific interests lie mostly in Molecular biology, Gene, Receptor, Ovalbumin and DNA. The Molecular biology study combines topics in areas such as Complementary DNA, Messenger RNA, Intracellular, Cell biology and Antibody. In the subject of general Complementary DNA, his work in cDNA library is often linked to Trefoil factor 2, MCF-7 and Estrogen receptor, thereby combining diverse domains of study.

While the research belongs to areas of Messenger RNA, he spends his time largely on the problem of Signal peptide, intersecting his research to questions surrounding Polyadenylation. His study on Gene is covered under Genetics. His Receptor study combines topics from a wide range of disciplines, such as Butyrophilin, Gene knockdown and Antigen.

His most cited work include:

Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries. (846 citations)
Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line. (655 citations)
The ovalbumin gene - sequence of putative control regions (643 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Molecular biology, Gene, Exon, RNA splicing and Alternative splicing. His study in Molecular biology is interdisciplinary in nature, drawing from both Gene expression, RNA, Complementary DNA, Receptor and Messenger RNA. His work is dedicated to discovering how Receptor, Antibody are connected with Cell biology and other disciplines.

His Gene research is multidisciplinary, relying on both Ovalbumin and DNA. His studies deal with areas such as Mutation and Intron as well as Exon. Richard Breathnach interconnects T cell and Antigen in the investigation of issues within Virus.

He most often published in these fields:

Molecular biology (78.69%)
Gene (34.43%)
Exon (34.43%)

What were the highlights of his more recent work (between 2003-2014)?

Cell biology (42.62%)
Molecular biology (78.69%)
Intracellular (29.51%)

In recent papers he was focusing on the following fields of study:

Richard Breathnach spends much of his time researching Cell biology, Molecular biology, Intracellular, Receptor and Antigen. His work carried out in the field of Cell biology brings together such families of science as T cell, MHC restriction, Natural killer cell and CD8. His T cell research includes themes of Protein structure, Plasma protein binding, Biochemistry, MHC class I and Protein engineering.

His Molecular biology study incorporates themes from Exonic splicing enhancer, RNA splicing, Alternative splicing and Exon. Richard Breathnach has researched Intracellular in several fields, including HEK 293 cells, Butyrophilin, Antibody and Gene knockdown. His biological study spans a wide range of topics, including Ribonucleoprotein, snRNP and splice.

Between 2003 and 2014, his most popular works were:

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset (310 citations)
Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset (310 citations)
Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset (310 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries.

R Breathnach;C Benoist;K O'Hare;F Gannon.
Proceedings of the National Academy of Sciences of the United States of America (1978)

1453 Citations

The ovalbumin gene - sequence of putative control regions

C. Benoist;K. O'Hare;R. Breathnach;Pierre Chambon.
Nucleic Acids Research (1980)

1133 Citations

Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line.

P Masiakowski;R Breathnach;J Bloch;F Gannon.
Nucleic Acids Research (1982)

892 Citations

Ovalbumin gene is split in chicken DNA

R. Breathnach;J. L. Mandel;P. Chambon.
Nature (1977)

553 Citations

Transformation of mouse fibroblasts to methotrexate resistance by a recombinant plasmid expressing a prokaryotic dihydrofolate reductase

K O'Hare;C Benoist;R Breathnach.
Proceedings of the National Academy of Sciences of the United States of America (1981)

526 Citations

The collagenase gene family in humans consists of at least four members.

D Muller;B Quantin;M C Gesnel;R Millon-Collard.
Biochemical Journal (1988)

493 Citations

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset

Christelle Harly;Christelle Harly;Christelle Harly;Yves Guillaume;Steven Nedellec;Steven Nedellec;Steven Nedellec;Cassie-Marie Peigné;Cassie-Marie Peigné;Cassie-Marie Peigné.
Blood (2012)

469 Citations

Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts

L M Matrisian;P Leroy;C Ruhlmann;M C Gesnel.
Molecular and Cellular Biology (1986)

436 Citations

Organisation and sequences at the 5′ end of a cloned complete ovalbumin gene

F. Gannon;K. O'Hare;F. Perrin;J. P. LePennec.
Nature (1979)

404 Citations

Sequence of the pS2 mRNA induced by estrogen in the human breast cancer cell line MCF-7

Sonia B. Jakowlew;Richard Breathnach;Jean-Marc Jeltsch;Piotr Masiakowski.
Nucleic Acids Research (1984)