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Pontus Aspenström

Pontus Aspenström

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
11981
World Ranking
17014
National Ranking
265

Overview

Pontus Aspenström is affiliated with the Karolinska Institute in Sweden and has contributed to research primarily within the fields of biochemistry, genetics, molecular biology, and medicine. Their work spans several specialized subfields, including molecular biology, pulmonary and respiratory medicine, cell biology, oncology, and immunology.

The research topics covered by Aspenström focus on occupational and environmental lung diseases, cancer-related molecular pathways, cellular mechanics and interactions, cancer cells and metastasis, microtubule and mitosis dynamics, interstitial lung diseases and idiopathic pulmonary fibrosis, as well as immune response and inflammation.

Scientific publications by Aspenström include the following recent papers:

  • Diabetes downregulates the antimicrobial peptide psoriasin and increases E. coli burden in the urinary bladder (2022, Nature Communications)
  • The Role of Fast-Cycling Atypical RHO GTPases in Cancer (2022, Cancers)
  • Syndecan-1 Overexpressing Mesothelioma Cells Inhibit Proliferation, Wound Healing, and Tube Formation of Endothelial Cells (2021, Cancers)
  • Altered cytoskeletal status in the transition from proneural to mesenchymal glioblastoma subtypes (2022, Scientific Reports)
  • Cytoskeletal Organization Correlates to Motility and Invasiveness of Malignant Mesothelioma Cells (2021, Cancers)

Frequent collaborators include Anders Hjerpe, Katalin Dobra, Soumitra Mohanty, Andrea Scheffschick, and Jonas Tovi.

Papers authored by Aspenström have appeared predominantly in the following venues:

  • Cancers
  • Nature Communications
  • Scientific Reports
  • Cells
  • Cellular and Molecular Life Sciences

Best Publications

  • Miro1 Is a Calcium Sensor for Glutamate Receptor-Dependent Localization of Mitochondria at Synapses

    Andrew F. MacAskill;Johanne E. Rinholm;Alison E. Twelvetrees;I. Lorena Arancibia-Carcamo

  • Rac and Cdc42 Induce Actin Polymerization and G1 Cell Cycle Progression Independently of p65PAK and the JNK/SAPK MAP Kinase Cascade

    Nathalie Lamarche;Nicolas Tapon;Lisa Stowers;Peter D Burbelo

  • Transforming Growth Factor-β–induced Mobilization of Actin Cytoskeleton Requires Signaling by Small GTPases Cdc42 and RhoA

    Sofia Edlund;Maréne Landström;Carl-Henrik Heldin;Pontus Aspenström

  • Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase

    Masao Saotome;Dzhamilja Safiulina;György Szabadkai;Sudipto Das

  • The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking.

    Åsa Fransson;Aino Ruusala;Pontus Aspenström

  • Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott–Aldrich syndrome

    Pontus Aspenström;Uno Lindberg;Alan Hall

  • Rho GTPases have diverse effects on the organization of the actin filament system.

    Pontus Aspenström;Asa Fransson;Jan Saras

  • Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis

    Åsa Fransson;Aino Ruusala;Pontus Aspenström

  • Effectors for the Rho GTPases

    Pontus Aspenström

  • The MAP kinase kinase kinase MLK2 co‐localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3

    Koh‐ichi Nagata;Axel Puls;Clare Futter;Pontus Aspenstrom

  • Transforming Growth Factor-β1 (TGF-β)–induced Apoptosis of Prostate Cancer Cells Involves Smad7-dependent Activation of p38 by TGF-β-activated Kinase 1 and Mitogen-activated Protein Kinase Kinase 3

    Sofia Edlund;Shizhong Bu;Norbert Schuster;Pontus Aspenström

  • A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton.

    Pontus Aspenström

  • Taking Rho GTPases to the next level: the cellular functions of atypical Rho GTPases.

    Pontus Aspenström;Aino Ruusala;Dirk Pacholsky

  • The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1.

    Ann-Sofi Johansson;Mariette Driessens;Pontus Aspenström

  • The Rho GTPases have multiple effects on the actin cytoskeleton

    Pontus Aspenström

  • A Novel GTPase-activating Protein for Rho Interacts with a PDZ Domain of the Protein-tyrosine Phosphatase PTPL1

    Jan Saras;Petra Franzén;Pontus Aspenström;Ulf Hellman

  • Angiomotin regulates endothelial cell migration during embryonic angiogenesis

    Karin Aase;Mira Ernkvist;Lwaki Ebarasi;Lars Jakobsson

  • Rich, a rho GTPase-activating protein domain-containing protein involved in signaling by Cdc42 and Rac1.

    Ninna Richnau;Pontus Aspenström

  • Interaction between Smad7 and β-Catenin: Importance for Transforming Growth Factor β-Induced Apoptosis

    Sofia Edlund;So Young Lee;Susanne Grimsby;Shouthing Zhang

  • Estrogen Supports Urothelial Defense Mechanisms

    Petra Lüthje;Hanna Brauner;Nubia L. Ramos;Amanda Övregaard

Frequent Co-Authors

Carl-Henrik Heldin
Carl-Henrik Heldin Uppsala University
Uno Lindberg
Uno Lindberg Stockholm University
Ulf Hellman
Ulf Hellman Ludwig Cancer Research
Alan Hall
Alan Hall Memorial Sloan Kettering Cancer Center
Sonia Ramos
Sonia Ramos Spanish National Research Council
Arne Östman
Arne Östman Karolinska Institute
Sven Pettersson
Sven Pettersson Karolinska Institute
David Attwell
David Attwell University College London
Howard J. Federoff
Howard J. Federoff University of California, Irvine
Philippe J. Sansonetti
Philippe J. Sansonetti Institut Pasteur

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