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Medicine

D-Index
85
Citations
23323
World Ranking
14722
National Ranking
7447

Overview

Klaus Faßbender is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on medicine with significant contributions to specialized subfields including neurology, epidemiology, molecular biology, physiology, and rehabilitation.

The scientist's body of work covers a range of topics within neurological and medical research. Key areas of focus include acute ischemic stroke management, stroke rehabilitation and recovery, Alzheimer's disease research and treatments, traumatic brain injury and neurovascular disturbances, Parkinson's disease mechanisms and treatments, venous thromboembolism diagnosis and management, and mechanisms of neuroinflammation and neurodegeneration.

Some of the recent papers authored or co-authored by Klaus Faßbender illustrate the scope and impact of their research:

  • "Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells," 2020, Cell Reports Medicine
  • "Decreased pH in the aging brain and Alzheimer's disease," 2021, Neurobiology of Aging
  • "Comparison of Mobile Stroke Unit With Usual Care for Acute Ischemic Stroke Management," 2022, JAMA Neurology
  • "Effects of Resistant Starch on Symptoms, Fecal Markers, and Gut Microbiota in Parkinson's Disease - The RESISTA-PD Trial," 2021, Genomics Proteomics & Bioinformatics
  • "Prehospital stroke management in the thrombectomy era," 2020, The Lancet Neurology

Klaus Faßbender has collaborated extensively with several frequent co-authors that have contributed to their research output. These include:

  • Silke Walter
  • Johannes Kornhuber
  • Janine Diehl-Schmid
  • Johannes Prudlo
  • Markus Otto

The scientist's publications are often featured in venues known for neurological and medical research, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Neurology
  • Alzheimer's & Dementia
  • Journal of Neurology
  • Journal of the Neurological Sciences

The overall research output by Klaus Faßbender encompasses a strong emphasis on neurology, reflected in more than seventy publications in this field. Their work addresses complex challenges in acute stroke care and neurodegenerative diseases, linking clinical management with underlying biological mechanisms.

Best Publications

  • Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo

    K. Fassbender;M. Simons;C. Bergmann;M. Stroick

  • Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls.

    Marcus M. Unger;Jörg Spiegel;Klaus-Ulrich Dillmann;David Grundmann

  • Proinflammatory cytokines in serum of patients with acute cerebral ischemia: kinetics of secretion and relation to the extent of brain damage and outcome of disease

    Klaus Fassbender;Siegbert Rossol;Thomas Kammer;Michael Daffertshofer

  • TLR2 Is a Primary Receptor for Alzheimer’s Amyloid β Peptide To Trigger Neuroinflammatory Activation

    Shirong Liu;Yang Liu;Wenlin Hao;Lisa Wolf

  • LPS receptor (CD14): a receptor for phagocytosis of Alzheimer’s amyloid peptide

    Yang Liu;Silke Walter;Massimiliano Stagi;Dmitry Cherny

  • The LPS receptor (CD14) links innate immunity with Alzheimer's disease.

    K. Fassbender;S. Walter;S. Kühl;S. Kühl;R. Landmann

  • Inflammatory cytokines in subarachnoid haemorrhage: association with abnormal blood flow velocities in basal cerebral arteries.

    K Fassbender;B Hodapp;S Rossol;T Bertsch

  • Streamlining of prehospital stroke management: the golden hour.

    Klaus Fassbender;Clotilde Balucani;Silke Walter;Steven R Levine

  • Pattern of activation of the hypothalamic-pituitary-adrenal axis in acute stroke. Relation to acute confusional state, extent of brain damage, and clinical outcome.

    K Fassbender;R Schmidt;R Mössner;M Daffertshofer

  • Mood disorders and dysfunction of the hypothalamic-pituitary-adrenal axis in multiple sclerosis : Association with cerebral inflammation

    Klaus Fassbender;Roland Schmidt;Reinald Mößner;Udo Kischka

  • Homocysteine in cerebral macroangiography and microangiopathy.

    Klaus Faβbender;Orell Mielke;Thomas Bertsch;Michael Hennerici

  • Circulating Selectin- and Immunoglobulin-Type Adhesion Molecules in Acute Ischemic Stroke

    Klaus Fassbender;Rainald Mössner;Lilian Motsch;Udo Kischka

  • Leakage of brain-originated proteins in peripheral blood: temporal profile and diagnostic value in early ischemic stroke

    Klaus Fassbender;Roland Schmidt;Andreas Schreiner;Mark Fatar

  • Fecal markers of intestinal inflammation and intestinal permeability are elevated in Parkinson's disease

    Andreas Schwiertz;Jörg Spiegel;Ulrich Dillmann;David Grundmann

  • Innate immune receptor expression in normal brain aging

    M. Letiembre;W. Hao;Y. Liu;S. Walter

  • e-ASPECTS software is non-inferior to neuroradiologists in applying the ASPECT score to computed tomography scans of acute ischemic stroke patients.

    Simon Nagel;Devesh Sinha;Diana Day;Wolfgang Reith

  • Mobile stroke units for prehospital thrombolysis, triage, and beyond: benefits and challenges

    Klaus Fassbender;James C Grotta;Silke Walter;Iris Q Grunwald;Iris Q Grunwald

  • Endothelin-1 in Subarachnoid Hemorrhage An Acute-Phase Reactant Produced by Cerebrospinal Fluid Leukocytes

    Klaus Fassbender;Britta Hodapp;Siegbert Rossol;Thomas Bertsch

  • Enlarged substantia nigra hyperechogenicity and risk for Parkinson disease: a 37-month 3-center study of 1847 older persons.

    Daniela Berg;Klaus Seppi;Stefanie Behnke;Inga Liepelt

  • Nocturnal plasma levels of cytokines in healthy men

    Susanne Gudewill;Thomas Pollmächer;Helmut Vedder;Wolfgang Schreiber

Frequent Co-Authors

Andreas Keller
Andreas Keller Saarland University
Eckart Meese
Eckart Meese Saarland University
Jörn Walter
Jörn Walter Saarland University
Francesco Brigo
Francesco Brigo University of Verona
Martina Sester
Martina Sester Saarland University
Raffaele Nardone
Raffaele Nardone Paracelsus Medical University
Wolfgang H. Oertel
Wolfgang H. Oertel Philipp University of Marburg
Michael G. Hennerici
Michael G. Hennerici Heidelberg University

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