World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
80
Citations
25622
World Ranking
4039
National Ranking
1991

Medicine

D-Index
81
Citations
26769
World Ranking
16539
National Ranking
8310

Overview

Josef T. Prchal is affiliated with the University of Utah in the United States. Their research primarily focuses on medicine, with significant contributions in biochemistry, genetics, and molecular biology. Their work addresses various subfields, including genetics, hematology, molecular biology, physiology, and cancer research.

The scientist's publications cover a range of topics related to blood disorders and cellular physiology. Major topics explored in their research include myeloproliferative neoplasms diagnosis and treatment, chronic myeloid leukemia treatments, high altitude and hypoxia, erythrocyte function and pathophysiology, acute myeloid leukemia research, hemoglobinopathies and related disorders, and eosinophilic disorders and syndromes.

Prchal's recent papers include the following:

  • Recommendations for diagnosis and treatment of methemoglobinemia (2021, American Journal of Hematology)
  • How Do Red Blood Cells Die? (2021, Frontiers in Physiology)
  • Thrombotic, inflammatory, and HIF-regulated genes and thrombosis risk in polycythemia vera and essential thrombocythemia (2020, Blood Advances)
  • The transcriptional and regulatory identity of erythropoietin producing cells (2023, Nature Medicine)
  • Large-scale Identification of Clonal Hematopoiesis and Mutations Recurrent in Blood Cancers (2021, Blood Cancer Discovery)

Their frequent coauthors include:

  • Jihyun Song
  • Soo Jin Kim
  • Srinivas K. Tantravahi
  • Victor R. Gordeuk
  • Tsewang Tashi

Prchal has published extensively in several key venues:

  • Blood (32 publications)
  • American Journal of Hematology (11 publications)
  • Clinical Lymphoma Myeloma & Leukemia (8 publications)
  • HemaSphere (4 publications)
  • Blood Cells Molecules and Diseases (3 publications)

Best Publications

  • Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals

    Mervin C. Yoder;Laura E. Mead;Daniel Prater;Theresa R. Krier

  • Genetic Evidence for High-Altitude Adaptation in Tibet

    Tatum S. Simonson;Yingzhong Yang;Chad D. Huff;Haixia Yun

  • Essential role for Nix in autophagic maturation of erythroid cells

    Hector Sandoval;Perumal Thiagarajan;Swapan K. Dasgupta;Armin Schumacher

  • Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia

    Sonny O. Ang;Hua Chen;Kiichi Hirota;Victor R. Gordeuk

  • The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: A 17.5 year follow-up

    Martin H. Steinberg;William F. McCarthy;Oswaldo Castro;Samir K. Ballas

  • JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome–negative CML, and megakaryocytic leukemia

    Jaroslav Jelinek;Yasuhiro Oki;Vazganush Gharibyan;Vazganush Gharibyan;Vazganush Gharibyan;Carlos Bueso-Ramos

  • A genetic mechanism for Tibetan high-altitude adaptation

    Felipe R. Lorenzo;Chad Huff;Chad Huff;Mikko Myllymäki;Benjamin Olenchock

  • Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera.

    Robert Kralovics;Yongli Guan;Josef T Prchal

  • Somatic HIF2A gain-of-function mutations in paraganglioma with polycythemia

    Zhengping Zhuang;Chunzhang Yang;Felipe Lorenzo;Maria Merino

  • Angiotensin II stimulates proliferation of normal early erythroid progenitors.

    Michal Mrug;Tomas Stopka;Bruce A. Julian;Jaroslav F. Prchal

  • A common progenitor for human myeloid and lymphoid cells.

    J. T. Prchal;D. W. Throckmorton;A. J. Carroll;E. W. Fuson

  • Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors

    Victor R. Gordeuk;Adelina I. Sergueeva;Galina Y. Miasnikova;Daniel Okhotin

  • Hypoxia-inducible Factor-1 Deficiency Results in Dysregulated Erythropoiesis Signaling and Iron Homeostasis in Mouse Development

    Donghoon Yoon;Yves D. Pastore;Vladimir Divoky;Enli Liu

  • Regulated expression of microRNAs in normal and polycythemia vera erythropoiesis

    Hana Bruchova;Donghoon Yoon;Archana M. Agarwal;Joshua Mendell

  • Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload

    Martha P. Mims;Yongli Guan;Dagmar Pospisilova;Monika Priwitzerova

  • Effect of Corticosteroids on Cataract Formation

    Harold W. Skalka;Josef T. Prchal

  • Polycythemia vera is not initiated by JAK2V617F mutation.

    Roberto H. Nussenzveig;Sabina I. Swierczek;Jaroslav Jelinek;Amos Gaikwad

  • Allogeneic hematopoietic stem-cell transplantation with reduced-intensity conditioning in intermediate- or high-risk patients with myelofibrosis with myeloid metaplasia

    Damiano Rondelli;Giovanni Barosi;Andrea Bacigalupo;Josef T. Prchal

  • Copper deficiency masquerading as myelodysplastic syndrome.

    Xylina T Gregg;Vishnu T Reddy;Vishnu T Reddy;Josef T Prchal;Josef T Prchal

  • Fatal sickle cell crisis after granulocyte colony-stimulating factor administration

    Brian K. Adler;Donna E. Salzman;Matthew H. Carabasi;William P. Vaughan

Frequent Co-Authors

Victor R. Gordeuk
Victor R. Gordeuk University of Illinois at Chicago
Jaroslav Jelinek
Jaroslav Jelinek Coriell Institute For Medical Research
Andrew J. Carroll
Andrew J. Carroll University of Alabama at Birmingham
Srdan Verstovsek
Srdan Verstovsek The University of Texas MD Anderson Cancer Center
Robert D. Christensen
Robert D. Christensen University of Utah
Ronald Hoffman
Ronald Hoffman Mount Sinai Hospital
Alessandro M. Vannucchi
Alessandro M. Vannucchi University of Florence
Jean Pierre J. Issa
Jean Pierre J. Issa Temple University
Max D. Cooper
Max D. Cooper Emory University
Lynn B. Jorde
Lynn B. Jorde University of Utah

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