D-Index & Metrics Best Publications

John W. Huggins

United States Department of the Army
United States

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name Citations Publications World Ranking National Ranking

Immunology D-index 47 Citations 8,658 84 World Ranking 3485 National Ranking 1586

Overview

What is he best known for?

The fields of study he is best known for:

Virus
Internal medicine
Enzyme

John W. Huggins mainly investigates Virology, Virus, Orthopoxvirus, Poxviridae and Ebola virus. Virology and Immunology are frequently intertwined in his study. His research integrates issues of Cowpox, Cowpox virus and Monkeypox virus in his study of Poxviridae.

As part of one scientific family, John W. Huggins deals mainly with the area of Monkeypox virus, narrowing it down to issues related to the Monkeypox, and often ACAM2000, Dryvax and Smallpox vaccine. He combines subjects such as Lassa fever, Filoviridae and Gene gun with his study of Ebola virus. His biological study spans a wide range of topics, including Viremia, Antibody, Immunization, Immunoglobulin G and Viral load.

His most cited work include:

A Mouse Model for Evaluation of Prophylaxis and Therapy of Ebola Hemorrhagic Fever (431 citations)
Prospective, Double-Blind, Concurrent, Placebo-Controlled Clinical Trial of Intravenous Ribavirin Therapy of Hemorrhagic Fever with Renal Syndrome (323 citations)
Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox (279 citations)

What are the main themes of his work throughout his whole career to date?

John W. Huggins spends much of his time researching Virology, Virus, Immunology, Orthopoxvirus and Ribavirin. His work focuses on many connections between Virology and other disciplines, such as Microbiology, that overlap with his field of interest in Viral replication. He has researched Virus in several fields, including Interferon and Vaccination.

His work in the fields of Viremia and Viral load overlaps with other areas such as Smallpox vaccine and Macaque. His work in Orthopoxvirus addresses issues such as Poxviridae, which are connected to fields such as Cowpox virus, Chordopoxvirinae and Cowpox. His Ribavirin research is multidisciplinary, relying on both Viral disease, Gastroenterology and Chemotherapy.

He most often published in these fields:

Virology (85.23%)
Virus (54.55%)
Immunology (22.73%)

What were the highlights of his more recent work (between 2008-2017)?

Virology (85.23%)
Virus (54.55%)
Monkeypox virus (17.05%)

In recent papers he was focusing on the following fields of study:

Virology, Virus, Monkeypox virus, Immunology and Monkeypox are his primary areas of study. His Virology research incorporates themes from Gene and Microbiology. His Microbiology research is multidisciplinary, incorporating perspectives in Titer, Lectin and Marburgvirus.

Monkeypox virus is often connected to Orthopoxvirus in his work. John W. Huggins interconnects Tecovirimat and Poxviridae in the investigation of issues within Orthopoxvirus. His study in Immunology concentrates on Viremia and Viral load.

Between 2008 and 2017, his most popular works were:

Nonhuman Primates Are Protected from Smallpox Virus or Monkeypox Virus Challenges by the Antiviral Drug ST-246 (83 citations)
Experience with intravenous ribavirin in the treatment of hemorrhagic fever with renal syndrome in Korea. (71 citations)
ST-246 antiviral efficacy in a nonhuman primate monkeypox model: determination of the minimal effective dose and human dose justification. (65 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A Mouse Model for Evaluation of Prophylaxis and Therapy of Ebola Hemorrhagic Fever

Mike Bray;Kelly Davis;Thomas Geisbert;Connie Schmaljohn.
The Journal of Infectious Diseases (1998)

693 Citations

Prospective, Double-Blind, Concurrent, Placebo-Controlled Clinical Trial of Intravenous Ribavirin Therapy of Hemorrhagic Fever with Renal Syndrome

John W. Huggins;Chin Min Hsiang;Thomas M. Cosgriff;Mei Ying Guang.
The Journal of Infectious Diseases (1991)

518 Citations

Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox

Patricia L. Earl;Jeffrey L. Americo;Linda S. Wyatt;Leigh Anne Eller.
Nature (2004)

415 Citations

Prospects for Treatment of Viral Hemorrhagic Fevers with Ribavirin, a Broad-Spectrum Antiviral Drug

John W. Huggins.
Clinical Infectious Diseases (1989)

383 Citations

An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge

Guang Yang;Daniel C. Pevear;Marc H. Davies;Marc S. Collett.
Journal of Virology (2005)

354 Citations

Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.

Bjarne Gabrielsen;Bjarne Gabrielsen;Thomas P. Monath;John W. Huggins;Deborah F. Kefauver.
Journal of Natural Products (1992)

311 Citations

Potential antiviral therapeutics for smallpox, monkeypox and other orthopoxvirus infections.

Robert O Baker;Mike Bray;John W Huggins.
Antiviral Research (2003)

255 Citations

Cidofovir Protects Mice against Lethal Aerosol or Intranasal Cowpox Virus Challenge

Mike Bray;Mark Martinez;Donald F. Smee;Debbie Kefauver.
The Journal of Infectious Diseases (2000)

240 Citations

Passive immunization of Ebola virus-infected cynomolgus monkeys with immunoglobulin from hyperimmune horses

P. B. Jahrling;J. Geisbert;J. R. Swearengen;G. P. Jaax.
Archives of virology. Supplementum (1996)

237 Citations

Interferon-β 1a and SARS Coronavirus Replication

Lisa E. Hensley;Elizabeth A. Fritz;Peter B. Jahrling;Christopher L. Karp.
Emerging Infectious Diseases (2004)

232 Citations

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Frequent Co-Authors

External Links

Personal Website for John W. Huggins