John W. Huggins mainly investigates Virology, Virus, Orthopoxvirus, Poxviridae and Ebola virus. Virology and Immunology are frequently intertwined in his study. His research integrates issues of Cowpox, Cowpox virus and Monkeypox virus in his study of Poxviridae.
As part of one scientific family, John W. Huggins deals mainly with the area of Monkeypox virus, narrowing it down to issues related to the Monkeypox, and often ACAM2000, Dryvax and Smallpox vaccine. He combines subjects such as Lassa fever, Filoviridae and Gene gun with his study of Ebola virus. His biological study spans a wide range of topics, including Viremia, Antibody, Immunization, Immunoglobulin G and Viral load.
John W. Huggins spends much of his time researching Virology, Virus, Immunology, Orthopoxvirus and Ribavirin. His work focuses on many connections between Virology and other disciplines, such as Microbiology, that overlap with his field of interest in Viral replication. He has researched Virus in several fields, including Interferon and Vaccination.
His work in the fields of Viremia and Viral load overlaps with other areas such as Smallpox vaccine and Macaque. His work in Orthopoxvirus addresses issues such as Poxviridae, which are connected to fields such as Cowpox virus, Chordopoxvirinae and Cowpox. His Ribavirin research is multidisciplinary, relying on both Viral disease, Gastroenterology and Chemotherapy.
Virology, Virus, Monkeypox virus, Immunology and Monkeypox are his primary areas of study. His Virology research incorporates themes from Gene and Microbiology. His Microbiology research is multidisciplinary, incorporating perspectives in Titer, Lectin and Marburgvirus.
Monkeypox virus is often connected to Orthopoxvirus in his work. John W. Huggins interconnects Tecovirimat and Poxviridae in the investigation of issues within Orthopoxvirus. His study in Immunology concentrates on Viremia and Viral load.
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A Mouse Model for Evaluation of Prophylaxis and Therapy of Ebola Hemorrhagic Fever
Mike Bray;Kelly Davis;Thomas Geisbert;Connie Schmaljohn.
The Journal of Infectious Diseases (1998)
Prospective, Double-Blind, Concurrent, Placebo-Controlled Clinical Trial of Intravenous Ribavirin Therapy of Hemorrhagic Fever with Renal Syndrome
John W. Huggins;Chin Min Hsiang;Thomas M. Cosgriff;Mei Ying Guang.
The Journal of Infectious Diseases (1991)
Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox
Patricia L. Earl;Jeffrey L. Americo;Linda S. Wyatt;Leigh Anne Eller.
Prospects for Treatment of Viral Hemorrhagic Fevers with Ribavirin, a Broad-Spectrum Antiviral Drug
John W. Huggins.
Clinical Infectious Diseases (1989)
An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge
Guang Yang;Daniel C. Pevear;Marc H. Davies;Marc S. Collett.
Journal of Virology (2005)
Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.
Bjarne Gabrielsen;Bjarne Gabrielsen;Thomas P. Monath;John W. Huggins;Deborah F. Kefauver.
Journal of Natural Products (1992)
Potential antiviral therapeutics for smallpox, monkeypox and other orthopoxvirus infections.
Robert O Baker;Mike Bray;John W Huggins.
Antiviral Research (2003)
Cidofovir Protects Mice against Lethal Aerosol or Intranasal Cowpox Virus Challenge
Mike Bray;Mark Martinez;Donald F. Smee;Debbie Kefauver.
The Journal of Infectious Diseases (2000)
Passive immunization of Ebola virus-infected cynomolgus monkeys with immunoglobulin from hyperimmune horses
P. B. Jahrling;J. Geisbert;J. R. Swearengen;G. P. Jaax.
Archives of virology. Supplementum (1996)
Interferon-β 1a and SARS Coronavirus Replication
Lisa E. Hensley;Elizabeth A. Fritz;Peter B. Jahrling;Christopher L. Karp.
Emerging Infectious Diseases (2004)
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