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Immunology

D-Index
54
Citations
11263
World Ranking
3880
National Ranking
1778

Overview

John W. Huggins is affiliated with the United States Department of the Army in the United States. Their research primarily spans the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics, and Molecular Biology. Within these broad fields, they focus on the subfields of Virology, Epidemiology, and Molecular Biology.

The scientist's work revolves around key topics including:

  • Poxvirus research and outbreaks
  • Bacillus and Francisella bacterial research
  • Herpesvirus infections and treatments
  • Virology and viral diseases

John W. Huggins has contributed to multiple publications, with frequent appearances in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Neglected Tropical Diseases
  • Emerging Infectious Diseases
  • Frontiers in Microbiology
  • Pathogens

Recent published papers include:

  • Clinical characterization of human monkeypox infections in the Democratic Republic of the Congo, 2022, bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical characterization and placental pathology of mpox infection in hospitalized patients in the Democratic Republic of the Congo, 2023, PLoS Neglected Tropical Diseases
  • Congenital Mpox Syndrome (Clade I) in Stillborn Fetus after Placental Infection and Intrauterine Transmission, Democratic Republic of the Congo, 2008, 2023, Emerging Infectious Diseases
  • Development of a specific MPXV antigen detection immunodiagnostic assay, 2023, Frontiers in Microbiology
  • Design and Optimization of a Monkeypox virus Specific Serological Assay, 2023, Pathogens

The scientist collaborates frequently with other researchers, with the most frequent co-authors being:

  • Phillip R. Pittman
  • Placide Mbala Kingebeni
  • James W. Martin
  • Jean-Jacques Muyembe Tamfum
  • Mary G. Reynolds

Best Publications

  • A Mouse Model for Evaluation of Prophylaxis and Therapy of Ebola Hemorrhagic Fever

    Mike Bray;Kelly Davis;Thomas Geisbert;Connie Schmaljohn

  • Prospective, Double-Blind, Concurrent, Placebo-Controlled Clinical Trial of Intravenous Ribavirin Therapy of Hemorrhagic Fever with Renal Syndrome

    John W. Huggins;Chin Min Hsiang;Thomas M. Cosgriff;Mei Ying Guang

  • Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox

    Patricia L. Earl;Jeffrey L. Americo;Linda S. Wyatt;Leigh Anne Eller

  • An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge

    Guang Yang;Daniel C. Pevear;Marc H. Davies;Marc S. Collett

  • Prospects for Treatment of Viral Hemorrhagic Fevers with Ribavirin, a Broad-Spectrum Antiviral Drug

    John W. Huggins

  • Evaluation of Immune Globulin and Recombinant Interferon-α2b for Treatment of Experimental Ebola Virus Infections

    Peter B. Jahrling;Peter B. Jahrling;Peter B. Jahrling;Thomas Geisbert;Thomas Geisbert;J. B. Geisbert;J. B. Geisbert;J. R. Swearengen;J. R. Swearengen

  • Maternal and Fetal Outcomes Among Pregnant Women With Human Monkeypox Infection in the Democratic Republic of Congo.

    Placide K Mbala;John W Huggins;Therese Riu-Rovira;Steve M Ahuka

  • Potential antiviral therapeutics for smallpox, monkeypox and other orthopoxvirus infections.

    Robert O Baker;Mike Bray;John W Huggins

  • Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.

    Bjarne Gabrielsen;Bjarne Gabrielsen;Thomas P. Monath;John W. Huggins;Deborah F. Kefauver

  • Genomic variability of monkeypox virus among humans, Democratic Republic of the Congo.

    Jeffrey R. Kugelman;Sara C. Johnston;Prime M. Mulembakani;Neville Kisalu

  • Cidofovir Protects Mice against Lethal Aerosol or Intranasal Cowpox Virus Challenge

    Mike Bray;Mark Martinez;Donald F. Smee;Debbie Kefauver

  • Generation of eGFP expressing recombinant Zaire ebolavirus for analysis of early pathogenesis events and high-throughput antiviral drug screening

    Jonathan S. Towner;Jason Paragas;Jason E. Dover;Manisha Gupta

  • Interferon-β 1a and SARS Coronavirus Replication

    Lisa E. Hensley;Elizabeth A. Fritz;Peter B. Jahrling;Christopher L. Karp

  • Passive immunization of Ebola virus-infected cynomolgus monkeys with immunoglobulin from hyperimmune horses

    P. B. Jahrling;J. Geisbert;J. R. Swearengen;G. P. Jaax

  • Construction and characterization of chimeric tick-borne encephalitis/dengue type 4 viruses.

    Alexander G. Pletnev;Michael Bray;John Huggins;Ching-Juh Lai

  • DNA vaccines expressing either the GP or NP genes of Ebola virus protect mice from lethal challenge.

    Lorna Vanderzanden;Mike Bray;Deborah Fuller;Tim Roberts

  • Broad-spectrum antiviral activity of 2-beta-D-ribofuranosylselenazole-4-carboxamide, a new antiviral agent.

    J J Kirsi;J A North;P A McKernan;B K Murray

  • Haematological, biochemical and coagulation changes in mice, guinea-pigs and monkeys infected with a mouse-adapted variant of Ebola Zaire virus.

    M. Bray;S. Hatfill;L. Hensley;J.W. Huggins

  • Treatment of lethal Ebola virus infection in mice with a single dose of an S-adenosyl-l-homocysteine hydrolase inhibitor ☆

    Mike Bray;John Driscoll;John W. Huggins

  • Exploring the potential of variola virus infection of cynomolgus macaques as a model for human smallpox

    Peter B. Jahrling;Lisa E. Hensley;Mark J. Martinez;James W. LeDuc

Frequent Co-Authors

Mike Bray
Mike Bray National Institutes of Health
Robert W. Sidwell
Robert W. Sidwell Utah State University
Donald F. Smee
Donald F. Smee Utah State University
Lisa E. Hensley
Lisa E. Hensley National Institutes of Health
Peter B. Jahrling
Peter B. Jahrling National Institutes of Health
Peter B. Jahrling
Peter B. Jahrling National Institute of Allergy and Infectious Diseases
Thomas W. Geisbert
Thomas W. Geisbert The University of Texas Medical Branch at Galveston
Inger K. Damon
Inger K. Damon Centers for Disease Control and Prevention
David A. Relman
David A. Relman Stanford University
James W. LeDuc
James W. LeDuc The University of Texas Medical Branch at Galveston

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