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Microbiology

D-Index
67
Citations
26402
World Ranking
2227
National Ranking
923

Overview

Jing-Hsiung Ou is affiliated with the University of Southern California in the United States. Their research contributions primarily focus on medicine, with a particular emphasis on epidemiology, hepatology, immunology, surgery, and infectious diseases. The scientist's work covers several key topics, notably Hepatitis B virus studies, Hepatitis C virus research, liver disease diagnosis and treatment, autophagy in disease and therapy, immune cells in cancer, interferon and immune responses, and immune response and inflammation.

Their recent scholarly publications shed light on various aspects of viral pathogenesis, immune interactions, and cellular processes involved in hepatitis virus biology. Selected recent papers include:

  • Pathogenicity and virulence of Hepatitis B virus, 2022, Virulence
  • Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3, 2022, Cell Reports
  • Autophagic membranes participate in hepatitis B virus nucleocapsid assembly, precore and core protein trafficking, and viral release, 2022, Proceedings of the National Academy of Sciences
  • Autophagy in HCV Replication and Protein Trafficking, 2021, International Journal of Molecular Sciences
  • Hepatitis C virus and intracellular antiviral response, 2021, Current Opinion in Virology

Jing-Hsiung Ou's publications are frequently featured in journals such as Cell Reports, Current Opinion in Virology, Viruses, Virulence, and the Proceedings of the National Academy of Sciences. These venues highlight their focus on both clinical and molecular aspects of viral hepatitis and related immunological mechanisms.

The scientist collaborates regularly with several researchers, indicating active engagement within a professional network. Frequent co-authors include Yu-Chen Chuang, Kuen-Nan Tsai, Ji-Young Lee, Yumei Li, and Yanwen Zhu. This collaboration pattern suggests contributions to projects intersecting immunology, virology, and metabolic studies related to viral infections.

In summary, Jing-Hsiung Ou's body of work integrates study of viral hepatitis pathogenesis and immune modulation with a focus on the cellular pathways affected by Hepatitis B and C viruses. Their research engages with aspects of autophagy, immune cell metabolism, and antiviral responses, spanning both laboratory research and clinical implications within the fields of medicine and infectious diseases.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling

    Yousuke Ebina;Leland Ellis;Kurt Jarnagin;Marc Edery

  • Structure, sequence and expression of the hepatitis delta ( δ ) viral genome

    Kang-Sheng Wang;Qui-Lim Choo;Amy J. Weiner;Jing-Hsiung Ou

  • Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication.

    V. E. Buckwold;Z. Xu;M. Chen;T. S. B. Yen

  • Functions of autophagy in normal and diseased liver

    Mark J. Czaja;Wen Xing Ding;Terrence M. Donohue;Scott L. Friedman

  • Synthesis of a novel hepatitis C virus protein by ribosomal frameshift

    Zhenming Xu;Jinah Choi;T. S.Benedict Yen;Wen Lu

  • The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication

    Donna Sir;Yongjun Tian;Wen-ling Chen;David K. Ann

  • Hepatitis B virus gene function: the precore region targets the core antigen to cellular membranes and causes the secretion of the e antigen.

    Jing-Hsiung Ou;Orgad Laub;William J. Rutter

  • Mechanisms of Liver Injury. III. Oxidative stress in the pathogenesis of hepatitis C virus

    Jinah Choi;J.-H. James Ou

  • Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response

    Donna Sir;Wen-ling Chen;Jinah Choi;Takaji Wakita

  • Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-beta receptor.

    M. Matsumoto;T. Y. Hsieh;N. Zhu;T. VanArsdale

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Trans-activation of the human immunodeficiency virus long terminal repeat by the hepatitis B virus X protein

    E. Seto;T. S. B. Yen;B. M. Peterlin;Jing-Hsiung Ou

  • Mechanisms of Hepatitis B Virus Persistence.

    Unknown

  • Mechanism of Suppression of Hepatitis B Virus Precore RNA Transcription by a Frequent Double Mutation

    Jie Li;Victor E. Buckwold;Man-wai Hon;Jing-hsiung Ou

  • Reactive oxygen species suppress hepatitis C virus RNA replication in human hepatoma cells.

    Jinah Choi;Ki Jeong Lee;Yanyan Zheng;Ardath K. Yamaga

  • Differential Subcellular Localization of Hepatitis C Virus Core Gene Products

    S. Y. Lo;F. Masiarz;F. Masiarz;S. B. Hwang;M. M. C. Lai

  • Phosphorylation and nuclear localization of the hepatitis B virus core protein: significance of serine in the three repeated SPRRR motifs.

    W. Liao;Jing-Hsiung Ou

  • A signal peptide encoded within the precore region of hepatitis B virus directs the secretion of a heterogeneous population of e antigens in Xenopus oocytes

    David N. Standring;Jing-Hsiung Ou;Frank R. Masiarz;William J. Rutter

  • The arginine-rich domain of hepatitis B virus precore and core proteins contains a signal for nuclear transport.

    Chau-Ting Yeh;Yun-Fan Liaw;Jing-Hsiung Ou

  • Roles of the three major phosphorylation sites of hepatitis B virus core protein in viral replication.

    Yueh T. Lan;Jie Li;Wen-yeh Liao;Jing-hsiung Ou

Frequent Co-Authors

Min Chen
Min Chen National Institutes of Health
Michael M. C. Lai
Michael M. C. Lai Academia Sinica
William J. Rutter
William J. Rutter University of California, San Francisco
Eric J. Huang
Eric J. Huang University of California, San Francisco
Yun-Fan Liaw
Yun-Fan Liaw Chang Gung Memorial Hospital
Chau-Ting Yeh
Chau-Ting Yeh Chang Gung Memorial Hospital
John L. Gerin
John L. Gerin Georgetown University Medical Center
Michael Houghton
Michael Houghton University of Alberta
Chia-Ming Chu
Chia-Ming Chu Memorial Hospital of South Bend
Amy S. Lee
Amy S. Lee University of Southern California

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