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Jennifer J. Westendorf

Jennifer J. Westendorf

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
12253
World Ranking
13161
National Ranking
5615

Overview

Jennifer J. Westendorf is affiliated with the Mayo Clinic in the United States. Their research spans multiple fields with a primary focus on biochemistry, genetics, and molecular biology, supported by significant contributions in medicine. The scientist's work encompasses diverse subfields including molecular biology, rheumatology, oncology, genetics, and public health as they relate to bone health, disease mechanisms, and gene regulation.

The main research topics covered by Jennifer J. Westendorf include:

  • Bone Metabolism and Diseases
  • Osteoarthritis Treatment and Mechanisms
  • Histone Deacetylase Inhibitors Research
  • Knee injuries and reconstruction techniques
  • Bone health and treatments
  • Epigenetics and DNA Methylation
  • Cancer-related gene regulation

Frequent collaboration is observed with a group of coauthors, notably Katherine M. Arnold, Samantha Weaver, Elizabeth W. Bradley, Elizabeth L. Zars, and Earnest L. Taylor, each contributing to multiple publications alongside Westendorf.

Jennifer J. Westendorf has published extensively in several scientific journals. The most frequent publication venues include:

  • Journal of Bone and Mineral Research
  • Journal of Biological Chemistry
  • Current Osteoporosis Reports
  • Scientific Reports
  • Osteoarthritis and Cartilage

Among selected recent papers are:

  • "Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2," 2020, Journal of Biological Chemistry
  • "Inflammatory Processes Affecting Bone Health and Repair," 2023, Current Osteoporosis Reports
  • "The Musculoskeletal Knowledge Portal: Making Omics Data Useful to the Broader Scientific Community," 2020, Journal of Bone and Mineral Research
  • "GAS7 Deficiency Promotes Metastasis in MYCN-Driven Neuroblastoma," 2021, Cancer Research
  • "The intersection of aging and estrogen in osteoarthritis," 2025, npj Women's Health

The researcher's body of work addresses critical intersections of epigenetics, bone biology, cancer genetics, and inflammatory processes. Their publications reflect interdisciplinary approaches combining molecular biology techniques with clinical applications in rheumatology and oncology.

Best Publications

  • Wnt signaling in osteoblasts and bone diseases

    Jennifer J. Westendorf;Rachel A. Kahler;Tania M. Schroeder

  • Sarcoma derived from cultured mesenchymal stem cells

    Jakub Tolar;Alma J. Nauta;Mark J. Osborn;Angela Panoskaltsis Mortari

  • Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate

    Larry Pederson;Ming Ruan;Jennifer J. Westendorf;Sundeep Khosla

  • ETO, a Target of t(8;21) in Acute Leukemia, Interacts with the N-CoR and mSin3 Corepressors

    Bart Lutterbach;Jennifer J. Westendorf;Bryan Linggi;Andrea Patten

  • Update on Wnt signaling in bone cell biology and bone disease

    David G. Monroe;Meghan E. McGee-Lawrence;Merry Jo Oursler;Jennifer J. Westendorf

  • Building bone to reverse osteoporosis and repair fractures

    Sundeep Khosla;Jennifer J. Westendorf;Merry Jo Oursler

  • Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter.

    Jennifer J. Westendorf;S. Kaleem Zaidi;Jonathan E. Cascino;Rachel Kahler

  • Runx2: a master organizer of gene transcription in developing and maturing osteoblasts.

    Tania M. Schroeder;Eric D. Jensen;Jennifer J. Westendorf

  • The t(8;21) Fusion Product, AML-1–ETO, Associates with C/EBP-α, Inhibits C/EBP-α-Dependent Transcription, and Blocks Granulocytic Differentiation

    Jennifer J. Westendorf;Cindy M. Yamamoto;Noel Lenny;James R. Downing

  • Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice

    Ming Xu;Elizabeth W. Bradley;Megan M. Weivoda;Soyun M. Hwang

  • Wnt signaling as a therapeutic target for bone diseases

    Luke H Hoeppner;Frank J Secreto;Jennifer J Westendorf

  • A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia.

    Bart Lutterbach;Jennifer J. Westendorf;Bryan Linggi;Stuart Isaac

  • Histone Deacetylase Inhibitors Promote Osteoblast Maturation

    Tania M Schroeder;Jennifer J Westendorf

  • Lymphoid Enhancer Factor-1 and β-Catenin Inhibit Runx2-dependent Transcriptional Activation of the Osteocalcin Promoter

    Rachel A. Kahler;Jennifer J. Westendorf

  • Histone Deacetylase 3 Interacts with Runx2 to Repress the Osteocalcin Promoter and Regulate Osteoblast Differentiation

    Tania M. Schroeder;Rachel A. Kahler;Xiaodong Li;Jennifer J. Westendorf

  • Mesenchymal stem cells for bone repair and metabolic bone diseases.

    Anita H. Undale;Jennifer J. Westendorf;Michael J. Yaszemski;Sundeep Khosla

  • Regulation of gene expression in osteoblasts

    Eric D. Jensen;Rajaram Gopalakrishnan;Jennifer J. Westendorf

  • The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas.

    Dong Fang;Haiyun Gan;Jeong Heon Lee;Jing Han

  • MicroRNA functions in osteogenesis and dysfunctions in osteoporosis.

    Andre J. Van Wijnen;Jeroen Van De Peppel;Johannes P. Van Leeuwen;Jane B. Lian

  • Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein.

    Randy Fenrick;Joseph M. Amann;Bart Lutterbach;Lilin Wang

Frequent Co-Authors

Scott W. Hiebert
Scott W. Hiebert Vanderbilt University
Jane B. Lian
Jane B. Lian University of Vermont
Gary S. Stein
Gary S. Stein University of Vermont
Sundeep Khosla
Sundeep Khosla Mayo Clinic
Andre J. Van Wijnen
Andre J. Van Wijnen University of Connecticut Health Center
Rajiv Kumar
Rajiv Kumar Mayo Clinic
James R. Downing
James R. Downing St. Jude Children's Research Hospital
Betsy A. Hirsch
Betsy A. Hirsch University of Minnesota
Mark A. Kay
Mark A. Kay Stanford University

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