Jeffrey W. Smith

Overview

Best Publications

• Ligand binding to integrins.

  Edward F. Plow;Thomas A. Haas;Li Zhang;Joseph Loftus

  1979
  Citations

• S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death.

  Zezong Gu;Marcus Kaul;Boxu Yan;Steven J. Kridel

  1200
  Citations

• Orlistat Is a Novel Inhibitor of Fatty Acid Synthase with Antitumor Activity

  Steven J. Kridel;Fumiko Axelrod;Natasha Rozenkrantz;Jeffrey W. Smith

  768
  Citations

• Integrin activation controls metastasis in human breast cancer

  Brunhilde Felding-Habermann;Timothy E. O'Toole;Jeffrey W. Smith;Emilia Fransvea

  760
  Citations

• MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells.

  Elena I. Deryugina;Boris Ratnikov;Edward Monosov;Tanya I. Postnova

  517
  Citations

• A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells

  David A. Cheresh;Jeffrey W. Smith;Helen M. Cooper;Vito Quaranta

  424
  Citations

• The vitronectin receptor alpha v beta 3 binds fibronectin and acts in concert with alpha 5 beta 1 in promoting cellular attachment and spreading on fibronectin.

  I F Charo;L Nannizzi;J W Smith;D A Cheresh

  418
  Citations

• Polymer particle shape independently influences binding and internalization by macrophages

  Gaurav Sharma;David T. Valenta;Yoav Altman;Sheryl Harvey

  405
  Citations

• Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect.

  David A. Scott;Adam D. Richardson;Fabian V. Filipp;Christine A. Knutzen

  382
  Citations

• Mitochondrial p32 Protein Is a Critical Regulator of Tumor Metabolism via Maintenance of Oxidative Phosphorylation

  Valentina Fogal;Adam D. Richardson;Priya P. Karmali;Immo E. Scheffler

  347
  Citations

• Ligand and cation binding are dual functions of a discrete segment of the integrin β3 subunit: Cation displacement is involved in ligand binding

  Stanley E. D'Souza;Thomas A. Haas;Randolph S. Piotrowicz;Vicky Byers-Ward

  307
  Citations

• Identification of a novel integrin binding site in fibronectin. Differential utilization by beta 3 integrins.

  R D Bowditch;M Hariharan;E F Tominna;J W Smith

  264
  Citations

• Substrate Hydrolysis by Matrix Metalloproteinase-9*

  Steven J. Kridel;Emily Chen;Lakshmi P. Kotra;Eric W. Howard

  252
  Citations

• Functional activation of integrin alpha V beta 3 in tumor cells expressing membrane-type 1 matrix metalloproteinase.

  Elena I. Deryugina;Mario A. Bourdon;Karli Jungwirth;Jeffrey W. Smith

  228
  Citations

• Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies.

  Young Joo Jeon;Sihem Khelifa;Boris Ratnikov;David A. Scott

  221
  Citations

• Correcting a Fundamental Flaw in the Paradigm for Antimicrobial Susceptibility Testing.

  Selvi C. Ersoy;Douglas M. Heithoff;Lucien Barnes;Geneva K. Tripp

  217
  Citations

• Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells

  Fabian V. Filipp;David A. Scott;Ze’ev A. Ronai;Andrei L. Osterman

  205
  Citations

• A Redox Site Involved in Integrin Activation

  Boxu Yan;Jeffrey W. Smith

  198
  Citations

• An Alternative Processing of Integrin αv Subunit in Tumor Cells by Membrane Type-1 Matrix Metalloproteinase

  Boris I. Ratnikov;Dmitri V. Rozanov;Tanya I. Postnova;Peter G. Baciu

  188
  Citations

• A Fatty Acid Synthase Blockade Induces Tumor Cell-cycle Arrest by Down-regulating Skp2

  Lynn M. Knowles;Fumiko Axelrod;Cecille D. Browne;Jeffrey W. Smith

  187
  Citations