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Immunology

D-Index
66
Citations
15487
World Ranking
2762
National Ranking
1314

Overview

James H. Finke is affiliated with the Cleveland Clinic Lerner College of Medicine in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with specific focus on subfields such as Immunology, Oncology, Surgery, Pulmonary and Respiratory Medicine, and Molecular Biology.

The scientist's research centers on topics including immune cells in cancer, renal cell carcinoma treatment, inflammatory biomarkers in disease prognosis, bladder and urothelial cancer treatments, cancer immunotherapy and biomarkers, CAR-T cell therapy research, and inflammation biomarkers and pathways.

Finke has published articles in several recognized venues. These include Frontiers in Oncology, Nature Reviews Nephrology, Targeted Oncology, Molecular Immunology, and Clinical Genitourinary Cancer. Among their frequent co-authors are Brian I. Rini, C. Marcela Díaz-Montero, Pat Rayman, Patricia Rayman, and Jin S. Kim.

Some of their recent notable papers are:

  • The immunology of renal cell carcinoma, 2020, Nature Reviews Nephrology
  • Tumor-Infiltrating Myeloid Cells Co-Express TREM1 and TREM2 and Elevated TREM-1 Associates With Disease Progression in Renal Cell Carcinoma, 2022, Frontiers in Oncology
  • Blood Myeloid-Derived Suppressor Cells Correlate with Neutrophil-to-Lymphocyte Ratio and Overall Survival in Metastatic Urothelial Carcinoma, 2020, Targeted Oncology
  • Healthy myeloid-derived suppressor cells express the surface ectoenzyme Vanin-2 (VNN2), 2021, Molecular Immunology
  • Myeloid-Derived Suppressor Cells in Nonmetastatic Urothelial Carcinoma of Bladder Is Associated With Pathologic Complete Response and Overall Survival, 2020, Clinical Genitourinary Cancer

Best Publications

  • Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients

    Jennifer S. Ko;Arnold H. Zea;Brian I. Rini;Joanna L. Ireland

  • Sunitinib Reverses Type-1 Immune Suppression and Decreases T-Regulatory Cells in Renal Cell Carcinoma Patients

    James H. Finke;Brian I Rini;Joanna Ireland;Patricia Rayman

  • Loss of T-Cell Receptor ζ Chain and p56lck in T-Cells Infiltrating Human Renal Cell Carcinoma

    James H. Finke;Arnold H. Zea;Jill Stanley;Dan L. Longo

  • The immunology of renal cell carcinoma

    C. Marcela Díaz-Montero;Brian I. Rini;James H. Finke

  • Direct and Differential Suppression of Myeloid-Derived Suppressor Cell Subsets by Sunitinib Is Compartmentally Constrained

    Jennifer S. Ko;Patricia Rayman;Joanna Ireland;Shadi Swaidani

  • Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma

    Baisakhi Raychaudhuri;Patricia Rayman;Joanna Ireland;Jennifer Ko

  • MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy.

    James Finke;Jennifer Ko;Brian Rini;Pat Rayman

  • Immunologic monitoring of cancer vaccine therapy: results of a workshop sponsored by the Society for Biological Therapy.

    Ulrich Keilholz;Jeffrey Weber;James H. Finke;Dmitry I. Gabrilovich

  • The CXC Chemokines IP-10 and Mig Are Necessary for IL-12-Mediated Regression of the Mouse RENCA Tumor

    Charles S. Tannenbaum;Raymond Tubbs;David Armstrong;James H. Finke

  • Disease-associated Bias in T Helper Type 1 (Th1)/Th2 CD4+ T Cell Responses Against MAGE-6 in HLA-DRB10401+ Patients With Renal Cell Carcinoma or Melanoma

    Tomohide Tatsumi;Lisa S. Kierstead;Elena Ranieri;Elena Ranieri;Loreto Gesualdo

  • The Cardioprotective Protein Apolipoprotein A1 Promotes Potent Anti-tumorigenic Effects

    Maryam Zamanian-Daryoush;Daniel J Lindner;Thomas C. Tallant;Zeneng Wang

  • Active surveillance in metastatic renal-cell carcinoma: a prospective, phase 2 trial

    Brian I Rini;Tanya B. Dorff;Paul Elson;Cristina Suarez Rodriguez

  • Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion

    Balint Otvos;Daniel J Silver;Erin E Mulkearns-Hubert;Alvaro G Alvarado

  • Where have all the T cells gone? Mechanisms of immune evasion by tumors

    James Finke;Soldano Ferrone;Alan Frey;Allan Mufson

  • T-Cells Infiltrating Renal Cell Carcinoma Display a Poor Proliferative Response Even Though They Can Produce Interleukin 2 and Express Interleukin 2 Receptors

    Jeannine P. Alexander;Seiji Kudoh;Kathryn A. Melsop;Thomas A. Hamilton

  • Myeloid-Derived Suppressor Cell Subset Accumulation in Renal Cell Carcinoma Parenchyma Is Associated with Intratumoral Expression of IL1β, IL8, CXCL5, and Mip-1α.

    Yana G. Najjar;Patricia Rayman;Xuefei Jia;Paul G. Pavicic

  • Cytokine and chemokine expression in tumors of mice receiving systemic therapy with IL-12.

    Charles S. Tannenbaum;Nancy Wicker;David Armstrong;Raymond Tubbs

  • Mechanisms of apoptosis in T cells from patients with renal cell carcinoma.

    Robert G. Uzzo;Patricia Rayman;Vladimir Kolenko;Peter E. Clark

  • Clinical Perspectives on Targeting of Myeloid Derived Suppressor Cells in the Treatment of Cancer

    Yana George Najjar;James Harold Finke

  • Defining the critical hurdles in cancer immunotherapy

    Bernard A. Fox;Bernard A. Fox;Dolores J. Schendel;Lisa H. Butterfield;Steinar Aamdal

Frequent Co-Authors

Ronald M. Bukowski
Ronald M. Bukowski Cleveland Clinic
Brian I. Rini
Brian I. Rini Vanderbilt University Medical Center
Raymond R. Tubbs
Raymond R. Tubbs Cleveland Clinic
Andrew C. Novick
Andrew C. Novick Cleveland Clinic
Walter J. Storkus
Walter J. Storkus University of Pittsburgh
Eric A. Klein
Eric A. Klein Cleveland Clinic
Marc S. Ernstoff
Marc S. Ernstoff Roswell Park Cancer Institute
Michael A. Vogelbaum
Michael A. Vogelbaum Cleveland Clinic
Peter A. Cohen
Peter A. Cohen Mayo Clinic
Steven C. Campbell
Steven C. Campbell Cleveland Clinic

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