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Immunology

D-Index
47
Citations
10912
World Ranking
4487
National Ranking
2029

Overview

Ignacio Sanz is affiliated with Emory University in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with significant contributions in Immunology, Infectious Diseases, and Rheumatology as well as Radiology, Nuclear Medicine and Imaging, and Neurology.

The main topics of Sanz's work focus on T-cell and B-cell Immunology, SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, and Systemic Lupus Erythematosus Research. Additional areas explored include Immune Cell Function and Interaction, Monoclonal and Polyclonal Antibodies Research, and the Long-Term Effects of COVID-19.

Sanz has published extensively in several prominent venues. Frequent publication outlets include bioRxiv (Cold Spring Harbor Laboratory), The Journal of Immunology, Immunity, Nature Immunology, and Nephrology Dialysis Transplantation.

Frequent collaborators in Sanz's research efforts include Matthew C. Woodruff, F. Eun-Hyung Lee, Doan C. Nguyen, Christopher M. Tipton, and Richard P. Ramonell.

  • Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19, 2020, Nature Immunology
  • Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein, 2020, Nature Medicine
  • Dysregulated naive B cells and de novo autoreactivity in severe COVID-19, 2022, Nature
  • Chronic inflammation, neutrophil activity, and autoreactivity splits long COVID, 2023, Nature Communications
  • Autoantibody-mediated impairment of DNASE1L3 activity in sporadic systemic lupus erythematosus, 2021, The Journal of Experimental Medicine

The research by Sanz and collaborators addresses important immunological mechanisms underlying infectious diseases and autoimmune conditions, emphasizing COVID-19 and systemic lupus erythematosus.

Best Publications

  • Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus

    Scott A. Jenks;Kevin S. Cashman;Esther Zumaquero;Urko M. Marigorta

  • Identification of a B cell signature associated with renal transplant tolerance in humans

    Kenneth A. Newell;Adam Asare;Allan D. Kirk;Trang D. Gisler

  • Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.

    Matthew C. Woodruff;Richard P. Ramonell;Doan C. Nguyen;Kevin S. Cashman

  • A New Population of Cells Lacking Expression of CD27 Represents a Notable Component of the B Cell Memory Compartment in Systemic Lupus Erythematosus

    Chungwen Wei;Jennifer Anolik;Amedeo Cappione;Bo Zheng

  • Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein.

    Seth J. Zost;Pavlo Gilchuk;Rita E. Chen;James Brett Case

  • Challenges and Opportunities for Consistent Classification of Human B Cell and Plasma Cell Populations.

    Ignacio Sanz;Chungwen Wei;Scott A. Jenks;Kevin S. Cashman

  • Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions

    I Sanz

  • Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function

    Silvia Portugal;Christopher M. Tipton;Haewon Sohn;Younoussou Kone

  • Advances in Human B Cell Phenotypic Profiling

    Denise A. Kaminski;Chungwen Wei;Yu Qian;Alexander F. Rosenberg

  • Polyclonal rabbit antithymocyte globulin triggers B-cell and plasma cell apoptosis by multiple pathways.

    Martin S. Zand;Thuong Vo;Jennifer Huggins;Raymond Felgar

  • Extrafollicular responses in humans and SLE

    Scott A. Jenks;Kevin S. Cashman;Matthew C. Woodruff;F. Eun‐Hyung Lee

  • Correction: Corrigendum: Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection

    Caitlin Bohannon;Ryan Powers;Lakshmipriyadarshini Satyabhama;Ang Cui

  • CpG DNA activation and plasma-cell differentiation of CD27- naive human B cells.

    Jennifer Huggins;Tina Pellegrin;Raymond E. Felgar;Chungwen Wei

  • Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A

    Mary Pulvino;Yue Liang;David Oleksyn;Michael DeRan

  • Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen.

    D P McCauliffe;F A Lux;T S Lieu;I Sanz

  • Comparison of D, JH, and junctional diversity in the fetal, adult, and aged B cell repertoires.

    Lynette A. Bangs;Ignacio E. Sanz;Judy M. Teale

  • IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation.

    Esther Zumaquero;Sara L Stone;Christopher D Scharer;Scott A Jenks

  • Expansion of Activated Peripheral Blood Memory B Cells in Rheumatoid Arthritis, Impact of B Cell Depletion Therapy, and Biomarkers of Response.

    Diana G. Adlowitz;Jennifer Barnard;Jamie N. Biear;Christopher Cistrone

  • Empirical advantages of adeno associated viral vectors in vivo gene therapy for arthritis.

    Jeffrey Goater;Rolf Müller;George Kollias;Gary S. Firestein

  • Dysregulated naive B cells and de novo autoreactivity in severe COVID-19

    Unknown

  • Peak frequencies of circulating human influenza-specific antibody secreting cells correlate with serum antibody response after immunization.

    Jessica L. Halliley;Shuya Kyu;James J. Kobie;Edward E. Walsh

  • Two Major Autoantibody Clusters in Systemic Lupus Erythematosus

    Kathryn H. Ching;Peter D. Burbelo;Christopher M. Tipton;Chungwen Wei

  • Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection

    Caitlin Bohannon;Ryan Powers;Lakshmipriyadarshini Satyabhama;Ang Cui

  • Autoantibody-mediated impairment of DNASE1L3 activity in sporadic systemic lupus erythematosus.

    Johannes Hartl;Lee Serpas;Yueyang Wang;Ali Rashidfarrokhi

  • The intersection of COVID-19 and autoimmunity.

    Jason S. Knight;Roberto Caricchio;Jean Laurent Casanova;Alexis J. Combes

  • Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein.

    Seth J Zost;Pavlo Gilchuk;Rita E Chen;James Brett Case

Frequent Co-Authors

Jennifer H. Anolik
Jennifer H. Anolik University of Rochester
Jeremy M. Boss
Jeremy M. Boss Emory University
Michelle Petri
Michelle Petri Johns Hopkins University School of Medicine
Frances E. Lund
Frances E. Lund University of Alabama at Birmingham
Michael C. Keefer
Michael C. Keefer University of Rochester
Troy D. Randall
Troy D. Randall University of Alabama at Birmingham
Edward E. Walsh
Edward E. Walsh University of Rochester Medical Center
Laurence A. Turka
Laurence A. Turka Harvard University
Ann R. Falsey
Ann R. Falsey University of Rochester
Jeffrey C. Edberg
Jeffrey C. Edberg University of Alabama at Birmingham

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