World's Best Scientists 2026 revealed!
Hirofumi Sawa

Hirofumi Sawa

D-Index & Metrics

Microbiology

D-Index
72
Citations
20476
World Ranking
1732
National Ranking
49

Overview

Hirofumi Sawa is a researcher affiliated with Hokkaido University in Japan. Their work predominantly focuses on the field of medicine, with a particular emphasis on infectious diseases and related subfields such as public health, environmental and occupational health, epidemiology, molecular biology, and virology.

The scientist's research covers several main topics, including:

  • SARS-CoV-2 and COVID-19 Research
  • Viral Infections and Vectors
  • Mosquito-borne diseases and control
  • Viral gastroenteritis research and epidemiology
  • COVID-19 Clinical Research Studies
  • Animal Virus Infections Studies
  • Rabies epidemiology and control

Hirofumi Sawa has contributed to numerous publications, with frequent appearances in journals such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Viruses
  • Pathogens
  • Scientific Reports
  • Journal of Virology

Several recent papers authored or co-authored by Sawa include:

  • "Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant," published in 2022 in Nature
  • "Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19," published in 2022 in Journal of Medicinal Chemistry
  • "Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike," published in 2022 in Cell
  • "Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants," published in 2023 in Nature Communications
  • "RIG-I triggers a signaling-abortive anti-SARS-CoV-2 defense in human lung cells," published in 2021 in Nature Immunology

The scientist has frequently collaborated with other researchers, including:

  • Michihito Sasaki
  • Yasuko Orba
  • Masahiro Kajihara
  • William W. Hall
  • Edgar Simulundu

Best Publications

  • Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

    Noboru Motoyama;Fanping Wang;Kevin A. Roth;Hirofumi Sawa

  • Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse

    Naomi Ohnishi;Hitomi Yuasa;Shinya Tanaka;Hirofumi Sawa

  • Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19

    Unknown

  • Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant

    Unknown

  • Gold Nanoparticles as a Vaccine Platform: Influence of Size and Shape on Immunological Responses in Vitro and in Vivo

    Kenichi Niikura;Tatsuya Matsunaga;Tadaki Suzuki;Shintaro Kobayashi

  • Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription.

    Hiroyuki Takai;Kazuhito Naka;Yuki Okada;Miho Watanabe

  • Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

    K Nakayama;I Negishi;K Kuida;H Sawa

  • Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike

    Unknown

  • Synthetic Double-Stranded RNA Poly(I:C) Combined with Mucosal Vaccine Protects against Influenza Virus Infection

    Takeshi Ichinohe;Izumi Watanabe;Izumi Watanabe;Satoshi Ito;Satoshi Ito;Hideki Fujii

  • Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I

    Hideki Hasegawa;Hirofumi Sawa;Martha J Lewis;Martha J Lewis;Yasuko Orba

  • The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

    Shigetomo Fukuhara;Szandor Simmons;Shunsuke Kawamura;Asuka Inoue

  • Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant

    Unknown

  • Induction of Plasminogen Activator Inhibitor Type-1 (PAI-1) by Proinsulin and Insulin In Vivo

    Thomas K. Nordt;Hirofumi Sawa;Satoshi Fujii;Burton E. Sobel

  • SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells.

    Michihito Sasaki;Kentaro Uemura;Akihiko Sato;Shinsuke Toba

  • RIG-I triggers a signaling-abortive anti-SARS-CoV-2 defense in human lung cells.

    Taisho Yamada;Seiichi Sato;Yuki Sotoyama;Yasuko Orba

  • Drug-Induced Long-QT Syndrome Associated With a Subclinical SCN5A Mutation

    Naomasa Makita;Minoru Horie;Takeshi Nakamura;Tomohiko Ai

  • Analysis of transforming activity of human synovial sarcoma-associated chimeric protein SYT-SSX1 bound to chromatin remodeling factor hBRM/hSNF2α

    Makoto Nagai;Shinya Tanaka;Masumi Tsuda;Shuichi Endo

  • Forkhead Transcription Factor FoxO1 in Adipose Tissue Regulates Energy Storage and Expenditure

    Jun Nakae;Yongheng Cao;Miyo Oki;Yasuko Orba

  • CalDAG-GEFIII activation of Ras, R-Ras, and Rap1

    Shigeko Yamashita;Naoki Mochizuki;Yusuke Ohba;Minoru Tobiume

  • The Human Polyoma JC Virus Agnoprotein Acts as a Viroporin

    Tadaki Suzuki;Yasuko Orba;Yuki Okada;Yuji Sunden

  • Virological characteristics of SARS-CoV-2 BA.2 variant

    Unknown

  • Cross-Protection against H5N1 Influenza Virus Infection Is Afforded by Intranasal Inoculation with Seasonal Trivalent Inactivated Influenza Vaccine

    Takeshi Ichinohe;Shin-Ichi Tamura;Akira Kawaguchi;Akira Kawaguchi;Akira Kawaguchi;Ai Ninomiya

  • Hydrocephalus, Situs Inversus, Chronic Sinusitis, and Male Infertility in DNA Polymerase λ-Deficient Mice: Possible Implication for the Pathogenesis of Immotile Cilia Syndrome

    Yosuke Kobayashi;Miho Watanabe;Yuki Okada;Hirofumi Sawa

  • Pertussis toxin-sensitive signal controls the trafficking of thymocytes across the corticomedullary junction in the thymus.

    Gen Suzuki;Hirofumi Sawa;Yoshiyasu Kobayashi;Yukiko Nakata

  • Flavivirus Encephalitis Pathological Aspects of Mouse and Other Animal Models

    T. Kimura;M. Sasaki;M. Okumura;E. Kim

Frequent Co-Authors

Yasuko Orba
Yasuko Orba Hokkaido University
Kazuo Nagashima
Kazuo Nagashima Hokkaido University
William W. Hall
William W. Hall University College Dublin
Ayato Takada
Ayato Takada Hokkaido University
Shinya Tanaka
Shinya Tanaka Hokkaido University
Tadaki Suzuki
Tadaki Suzuki National Institutes of Health
Hideki Hasegawa
Hideki Hasegawa National Institutes of Health
Tetsutaro Sata
Tetsutaro Sata National Institute of Infectious Diseases
Chihiro Sugimoto
Chihiro Sugimoto Hokkaido University
Takeshi Kurata
Takeshi Kurata Juntendo University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Microbiology in the USA opens doors to diverse career paths, but many students also explore complementary fields to broaden their expertise. For example, pursuing an online health information management degree programs cahiim accredited can equip graduates with essential skills in managing healthcare data, a rapidly growing area within the biomedical sector.

Additionally, for those interested in administrative roles in healthcare, fast-tracking credentials through an online medical billing and coding certificate fast program offers an efficient path to gain practical certification and enter the workforce quickly.

On the clinical side, students may consider exploring what medical degrees can i get online to understand the possibilities for further education without traditional on-campus attendance, helping to balance flexibility with hands-on experience.

For those passionate about public health, enrolling in one of the easy mph online programs to get into can be a strategic move to enhance career prospects in epidemiology, health policy, or environmental health, complementing a microbiology background.

Best Scientists Citing Hirofumi Sawa

Trending Scientists