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Gustav Gaudernack

Gustav Gaudernack

D-Index & Metrics

Immunology

D-Index
64
Citations
14841
World Ranking
2934
National Ranking
17

Overview

Gustav Gaudernack is affiliated with Ultimovacs in Norway, focusing on research in medicine, immunology, and molecular biology. Their primary fields of study are Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology, with specific subfields including Oncology, Immunology, Biotechnology, Molecular Biology, and Biomedical Engineering.

The scientist's research extensively covers topics such as Immunotherapy and Immune Responses, CAR-T cell therapy research, Cancer Immunotherapy and Biomarkers, Cancer Research and Treatments, Virus-based gene therapy research, vaccines and immunoinformatics approaches, and T-cell and B-cell Immunology.

Gustav Gaudernack has published several papers in a variety of scientific journals. Notable recent works include:

  • "Reactive oxygen species as an initiator of toxic innate immune responses in retort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine as early therapeutic intervention," 2020, Toxicology Reports
  • "Long-Term Outcomes of a Phase I Study With UV1, a Second Generation Telomerase Based Vaccine, in Patients With Advanced Non-Small Cell Lung Cancer," 2020, Frontiers in Immunology
  • "Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial," 2021, Frontiers in Immunology
  • "Telomerase as a Target for Therapeutic Cancer Vaccines and Considerations for Optimizing Their Clinical Potential," 2021, Frontiers in Immunology
  • "Durable and dynamic hTERT immune responses following vaccination with the long-peptide cancer vaccine UV1: long-term follow-up of three phase I clinical trials," 2022, Journal for ImmunoTherapy of Cancer

Their frequent co-authors include Else Marit Inderberg, Espen B. Ellingsen, Tormod Kyrre Guren, Eivind Hovig, and Sara M. Mangsbo. These collaborations have contributed to publications in prominent venues such as Frontiers in Immunology, Toxicology Reports, Nature Communications, Journal for ImmunoTherapy of Cancer, and Molecular Therapy.

Gustav Gaudernack's work in cancer immunotherapy includes both clinical and molecular research focusing on telomerase-based vaccines, immune responses, and therapeutic approaches integrating novel immunotherapeutic agents. The scope of the research addresses long-term patient outcomes, vaccine efficacy, and mechanisms underlying immune activation and tolerance in cancer and infectious diseases.

Best Publications

  • Therapeutic vaccines for cancer: an overview of clinical trials

    Ignacio Melero;Gustav Gaudernack;Winald Gerritsen;Christoph Huber

  • Photochemical internalization: a novel technology for delivery of macromolecules into cytosol.

    Kristian Berg;Pål Kristian Selbo;Lina Prasmickaite;Torunn E. Tjelle

  • Intradermal ras peptide vaccination with granulocyte‐macrophage colony‐stimulating factor as adjuvant: Clinical and immunological responses in patients with pancreatic adenocarcinoma

    Marianne K. Gjertsen;Trond Buanes;Arne R. Rosseland;Arne Bakka

  • Telomerase peptide vaccination of patients with non-resectable pancreatic cancer: A dose escalating phase I/II study.

    S. L. Bernhardt;M. K. Gjertsen;S. Trachsel;M. Møller

  • Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma.

    Einar Osland Vik-Mo;Marta Nyakas;Birthe Viftrup Mikkelsen;Birthe Viftrup Mikkelsen;Morten Carstens Moe

  • Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer

    Paal F. Brunsvig;Steinar Aamdal;Marianne K. Gjertsen;Gunnar Kvalheim

  • Frameshift-mutation-derived peptides as tumor-specific antigens in inherited and spontaneous colorectal cancer

    Ingvil Sæterdal;Jens Bjørheim;Kari Lislerud;Marianne K. Gjertsen

  • HLA class I and II typing using cells positively selected from blood by immunomagnetic isolation--a fast and reliable technique.

    Frode Vartdal;Gustav Gaudernack;Steinar Funderud;Anne Bratlie

  • In vitro differentiation of human monocytes. Differences in monocyte phenotypes induced by cultivation on glass or on collagen.

    Gilla Kaplan;Gustav Gaudernack

  • Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA.

    J. A. Kyte;L. Mu;Steinar Aamdal;Gunnar Kvalheim

  • Vaccination with mutant ras peptides and induction of T-cell responsiveness in pancreatic carcinoma patients carrying the corresponding RAS mutation

    M.K. Gjertsen;J. Breivik;I. Saeterdal;E. Thorsby

  • CD8+ T cells inhibit HIV replication in naturally infected CD4+ T cells: Evidence for a soluble inhibitor

    Jan E. Brinchmann;Gustav Gaudernack;Frode Vartdal

  • Cytotoxic CD4+ and CD8+ T lymphocytes, generated by mutant p21-ras (12Val) peptide vaccination of a patient, recognize 12Val-dependent nested epitopes present within the vaccine peptide and kill autologous tumour cells carrying this mutation.

    Marianne K. Gjertsen;Jens Bjørheim;Ingvil Saeterdal;June Helen Myklebust

  • Long-term follow-up of patients with resected pancreatic cancer following vaccination against mutant K-ras.

    Synne Wedén;Synne Wedén;Marianne Klemp;Marianne Klemp;Ivar P. Gladhaug;Ivar P. Gladhaug;Mona Møller

  • Telomerase peptide vaccination in NSCLC: a phase II trial in stage III patients vaccinated after chemoradiotherapy and an 8-year update on a phase I/II trial.

    Paal Fr. Brunsvig;Jon Amund Kyte;Christian Kersten;Stein Sundstrøm

  • Sialomucin CD34 is the major L-selectin ligand in human tonsil high endothelial venules.

    Kamal D. Puri;Erik B. Finger;Gustav Gaudernack;Timothy A. Springer

  • mRNA-based electrotransfection of human dendritic cells and induction of cytotoxic T lymphocyte responses against the telomerase catalytic subunit (hTERT)

    Stein Sæbøe-Larssen;Ellen Fossberg;Gustav Gaudernack

  • Telomerase Peptide Vaccination Combined with Temozolomide: A Clinical Trial in Stage IV Melanoma Patients

    Jon Amund Kyte;Gustav Gaudernack;Svein Dueland;Sissel Trachsel

  • Immune escape of cancer cells with beta2-microglobulin loss over the course of metastatic melanoma.

    Ana B. del Campo;Jon Amund Kyte;Javier Carretero;Svitlana Zinchencko

  • Identification and Characterization of Cells with Cancer Stem Cell Properties in Human Primary Lung Cancer Cell Lines

    Ping Wang;Quanli Gao;Zhenhe Suo;Zhenhe Suo;Else Munthe

  • Isolation of pure functionally active CD8+ T cells positive selection with monoclonal antibodies directly conjugated to monosized magnetic microspheres

    Gustav Gaudernack;Torbjørn Leivestad;John Ugelstad;Erik Thorsby

Frequent Co-Authors

Gunnar Kvalheim
Gunnar Kvalheim Oslo University Hospital
Erik Thorsby
Erik Thorsby Oslo University Hospital
Anne Spurkland
Anne Spurkland University of Oslo
Erlend B. Smeland
Erlend B. Smeland Oslo University Hospital
Ludvig M. Sollid
Ludvig M. Sollid Oslo University Hospital
Knut E.A. Lundin
Knut E.A. Lundin University of Oslo
Øystein Fodstad
Øystein Fodstad Oslo University Hospital
Per thor Straten
Per thor Straten University of Copenhagen
Sophie D. Fosså
Sophie D. Fosså Oslo University Hospital
Anne Lise Børresen-Dale
Anne Lise Børresen-Dale Oslo University Hospital

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