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Immunology

D-Index
53
Citations
9207
World Ranking
3999
National Ranking
28

Overview

Gunnar Kvalheim is affiliated with Oslo University Hospital in Norway. Their research focuses primarily on medicine, with a strong emphasis on immunology, microbiology, and biochemistry, genetics, and molecular biology. The scientist has contributed notably to multiple subfields, including oncology, immunology, molecular biology, pulmonary and respiratory medicine, and biomedical engineering.

Their research topics span several key areas in biomedical science and cancer therapy. These topics include:

  • CAR-T cell therapy research
  • Immunotherapy and immune responses
  • Cancer immunotherapy and biomarkers
  • RNA interference and gene delivery
  • Virus-based gene therapy research
  • Prostate cancer treatment and research
  • Nanowire synthesis and applications

Frequent coauthors collaborating with Kvalheim are:

  • Else Marit Inderberg
  • Sébastien Wälchli
  • Iris Bigalke
  • Dag Josefsen
  • Dolores J. Schendel

The scientist's publications appear in a number of journals, most notably:

  • Molecular Therapy
  • Nature Communications
  • Clinical & Translational Immunology
  • The Prostate
  • Leukemia

Selected recent papers by Gunnar Kvalheim include:

  • "Toll-like receptor 7/8-matured RNA-transduced dendritic cells as post-remission therapy in acute myeloid leukaemia: results of a phase I trial," 2020, Clinical & Translational Immunology
  • "ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma," 2023, Nature Communications
  • "Long-term first-in-man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high-risk prostate cancer after radical prostatectomy," 2021, The Prostate
  • "Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy," 2020, Molecular Therapy
  • "WT1 and PRAME RNA-loaded dendritic cell vaccine as maintenance therapy in de novo AML after intensive induction chemotherapy," 2023, Leukemia

Best Publications

  • Detection of Isolated Tumor Cells in Bone Marrow Is an Independent Prognostic Factor in Breast Cancer

    Gro Wiedswang;E. Borgen;R. Kåresen;Gunnar Kvalheim

  • Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo

    Petter S. Woll;Una Kjällquist;Onima Chowdhury;Helen Doolittle

  • Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma.

    Einar Osland Vik-Mo;Marta Nyakas;Birthe Viftrup Mikkelsen;Birthe Viftrup Mikkelsen;Morten Carstens Moe

  • Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer

    Paal F. Brunsvig;Steinar Aamdal;Marianne K. Gjertsen;Gunnar Kvalheim

  • Standardization of the immunocytochemical detection of cancer cells in BM and blood: I. establishment of objective criteria for the evaluation of immunostained cells

    E. Borgen;B. Naume;J.M. Nesland;G. Kvalheim

  • Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA.

    J. A. Kyte;L. Mu;Steinar Aamdal;Gunnar Kvalheim

  • Isolated tumor cells in bone marrow three years after diagnosis in disease-free breast cancer patients predict unfavorable clinical outcome.

    Gro Wiedswang;Elin Borgen;Rolf Kåresen;Hanne Qvist

  • High-dose therapy with autologous stem cell transplantation in patients with peripheral T cell lymphomas.

    A. K. Blystad;G. Enblad;S. Kvaløy;Å Berglund

  • Comparison of the clinical significance of occult tumor cells in blood and bone marrow in breast cancer.

    Gro Wiedswang;Elin Borgen;Cecilie Schirmer;Rolf Kåresen

  • Immunocytochemical detection of isolated epithelial cells in bone marrow: non-specific staining and contribution by plasma cells directly reactive to alkaline phosphatase.

    Elin Borgen;Klaus Beiske;Sissel Trachsel;Jahn M. Nesland

  • Identification and Characterization of Cells with Cancer Stem Cell Properties in Human Primary Lung Cancer Cell Lines

    Ping Wang;Quanli Gao;Zhenhe Suo;Zhenhe Suo;Else Munthe

  • Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer

    Bjørn Naume;Xi Zhao;Marit Synnestvedt;Elin Borgen

  • Immunomagnetic techniques for the enrichment and detection of isolated breast carcinoma cells in bone marrow and peripheral blood.

    Bjorn Naume;Elin Borgen;Klaus Beiske;Tove Karin Herstad

  • Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients

    L. J. Mu;J. A. Kyte;Gunnar Kvalheim;Steinar Aamdal

  • Depletion of T lymphocytes from human bone marrow: use of magnetic monosized polymer microspheres coated with T-lymphocyte-specific monoclonal antibodies

    Frode Vartdal;Gunnar Kvalheim;Tor E. Lea;Vidar Bosnes

  • Detection of cancer cells in effusions from patients diagnosed with gynaecological malignancies. Evaluation of five epithelial markers.

    Ben Davidson;Bjørn Risberg;Gunnar Kristensen;Gunnar Kvalheim

  • Detection of isolated tumor cells in bone marrow in early-stage breast carcinoma patients: Comparison with preoperative clinical parameters and primary tumor characteristics

    Bjørn Naume;Elin Borgen;Gunnar Kvalheim;Rolf Kåresen

  • hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes.

    Else M.Inderberg Suso;Svein Dueland;Anne Marie Rasmussen;Turid Vetrhus

  • Increased sensitivity for detection of micrometastases in bone-marrow/peripheral-blood stem-cell products from breast-cancer patients by negative immunomagnetic separation.

    Bjørn Naume;Elin Borgen;Jahn M. Nesland;Klaus Beiske

  • Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model

    H Almåsbak;E Walseng;A Kristian;M R Myhre

  • A TCR-based Chimeric Antigen Receptor.

    Even Walseng;Hakan Köksal;Ibrahim M. Sektioglu;Anne Fåne

  • METHOD FOR DETECTION OF SPECIFIC TARGET CELLS AND MEANS FOR REALISATION

    Fodstad Oystein;Kvalheim Gunnar

Frequent Co-Authors

Gustav Gaudernack
Gustav Gaudernack Ultimovacs (Norway)
Jahn M. Nesland
Jahn M. Nesland Oslo University Hospital
Øystein Fodstad
Øystein Fodstad Oslo University Hospital
Erlend B. Smeland
Erlend B. Smeland Oslo University Hospital
Jan Delabie
Jan Delabie University Health Network
Wolfgang Hiddemann
Wolfgang Hiddemann Ludwig-Maximilians-Universität München
Alexander Pihl
Alexander Pihl University of Oslo
Baldur Sveinbjørnsson
Baldur Sveinbjørnsson University of Tromsø - The Arctic University of Norway
Sten Eirik W. Jacobsen
Sten Eirik W. Jacobsen University of Oxford

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