World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
49
Citations
7556
World Ranking
2646
National Ranking
1290

Overview

Gagan Deep is affiliated with Wake Forest University in the United States. Their research focuses largely on the molecular and cellular mechanisms underlying cancer and related diseases, with a significant emphasis on extracellular vesicles, hypoxia in tumor microenvironments, and cancer therapeutics.

The primary fields of study for Gagan Deep are Biochemistry, Genetics and Molecular Biology, with 76 publications, followed by Medicine with 48 publications. Within these fields, their subfields of research include Molecular Biology, Cancer Research, Physiology, Pulmonary and Respiratory Medicine, and Biomedical Engineering.

The main research topics explored by Gagan Deep include:

  • Extracellular vesicles in disease
  • MicroRNA in disease regulation
  • Nanoplatforms for cancer theranostics
  • Circular RNAs in diseases
  • Prostate Cancer Treatment and Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Cancer-related molecular mechanisms research

Gagan Deep has collaborated frequently with other researchers, notably:

  • Ashish Kumar (34 coauthored works)
  • Sangeeta Singh (23 coauthored works)
  • Yixin Su (23 coauthored works)
  • Susy Kim (19 coauthored works)
  • Mitu Sharma (12 coauthored works)

Their recent scholarly publications include:

  • "Exosomes secreted by prostate cancer cells under hypoxia promote matrix metalloproteinases activity at pre-metastatic niches", 2020, Molecular Carcinogenesis
  • "Hypoxia in tumor microenvironment regulates exosome biogenesis: Molecular mechanisms and translational opportunities", 2020, Cancer Letters
  • "Breaking the barrier: an osmium photosensitizer with unprecedented hypoxic phototoxicity for real world photodynamic therapy", 2020, Chemical Science
  • "Near-infrared absorbing Ru(II) complexes act as immunoprotective photodynamic therapy (PDT) agents against aggressive melanoma", 2020, Chemical Science
  • "Exosomes in hypoxia-induced remodeling of the tumor microenvironment", 2020, Cancer Letters

Gagan Deep frequently publishes in venues that include:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Methods in molecular biology
  • Journal of Clinical Oncology

Best Publications

  • Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies.

    Vibha Rani;Gagan Deep;Rakesh K. Singh;Komaraiah Palle

  • Role of p53 in silibinin-mediated inhibition of ultraviolet B radiation-induced DNA damage, inflammation and skin carcinogenesis.

    Cynthia M. Rigby;Srirupa Roy;Srirupa Roy;Gagan Deep;Gagan Deep;Ruth Guillermo-Lagae

  • Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules

    Anand Ramteke;Harold Ting;Chapla Agarwal;Chapla Agarwal;Samiha Mateen

  • Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer

    Gagan Deep;Rajesh Agarwal

  • Silymarin and silibinin cause G1 and G2–M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin

    G Deep;R P Singh;C Agarwal;D J Kroll

  • Effect of Silibinin on the Growth and Progression of Primary Lung Tumors in Mice

    Rana P. Singh;Gagan Deep;Manesh Chittezhath;Manjinder Kaur

  • Chemopreventive efficacy of silymarin in skin and prostate cancer.

    Gagan Deep;Rajesh Agarwal

  • Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice.

    Komal Raina;Subapriya Rajamanickam;Gagan Deep;Meenakshi Singh

  • Circulating tumor cell-derived organoids: Current challenges and promises in medical research and precision medicine.

    Prakash P. Praharaj;Sujit K. Bhutia;Sunitha Nagrath;Rhonda L. Bitting

  • Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling.

    Rana P. Singh;Komal Raina;Gagan Deep;Daniel Chan

  • Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model.

    Komal Raina;Subapriya Rajamanickam;Rana P. Singh;Gagan Deep

  • Hypoxia in tumor microenvironment regulates exosome biogenesis: Molecular mechanisms and translational opportunities.

    Ashish Kumar;Gagan Deep;Gagan Deep

  • Hypoxia-Induced Signaling Promotes Prostate Cancer Progression: Exosomes Role as Messenger of Hypoxic Response in Tumor Microenvironment.

    Gagan Deep;Gati K Panigrahi

  • Hypoxia-induced exosome secretion promotes survival of African-American and Caucasian prostate cancer cells.

    Gati K. Panigrahi;Prakash P. Praharaj;Taylor C. Peak;Jessica Long

  • Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft

    Manjinder Kaur;Balaiya Velmurugan;Alpna Tyagi;Gagan Deep

  • Aberrant Lipid Metabolism Promotes Prostate Cancer: Role in Cell Survival under Hypoxia and Extracellular Vesicles Biogenesis.

    Gagan Deep;Isabel R Schlaepfer

  • Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation

    Arron Sikka;Manjinder Kaur;Chapla Agarwal;Gagan Deep

  • SNAI1 is critical for the aggressiveness of prostate cancer cells with low E-cadherin.

    Gagan Deep;Anil K Jain;Anand Ramteke;Anand Ramteke;Harold Ting

  • Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells

    Gagan Deep;Nicholas H. Oberlies;David J. Kroll;Rajesh Agarwal

  • Role of E-cadherin in antimigratory and antiinvasive efficacy of silibinin in prostate cancer cells.

    Gagan Deep;Subhash Chander Gangar;Chapla Agarwal;Rajesh Agarwal

Frequent Co-Authors

Rajesh Agarwal
Rajesh Agarwal University of Colorado Anschutz Medical Campus
Rana P. Singh
Rana P. Singh Jawaharlal Nehru University
Nicholas H. Oberlies
Nicholas H. Oberlies University of North Carolina at Greensboro
David J. Orlicky
David J. Orlicky University of Colorado Denver
Hariom Yadav
Hariom Yadav University of South Florida
Ravinder Nagpal
Ravinder Nagpal Florida State University
Nino Russo
Nino Russo University of Calabria
Robert H. Eckel
Robert H. Eckel University of Colorado Anschutz Medical Campus
Michael Pollak
Michael Pollak McGill University
Anthony Atala
Anthony Atala Wake Forest University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Molecular Biology often leads to diverse career paths within healthcare and research. For those interested in communication disorders, earning a asha accredited online slp programs degree can be an excellent option. These programs meet rigorous standards, preparing graduates for certified roles in speech-language pathology.

Even for students without a traditional background, a SLP bridge pathway for communication sciences graduates provides a route to join the field. These bridge programs allow individuals from non-SLP majors, such as molecular biology, to transition into clinical practice.

For those drawn to nursing, accelerated nursing programs for non nurses offer an efficient way to launch a career in nursing, regardless of your undergraduate major. These online options are both time-saving and cost-effective.

Graduates in biology-related fields looking to advance further may consider roles such as the psychiatric nurse practitioner, which offers strong earning potential. State-by-state salary breakdowns for this profession are available on psychiatric np salary resources.

Best Scientists Citing Gagan Deep

Trending Scientists