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Biology and Biochemistry

D-Index
60
Citations
12350
World Ranking
11997
National Ranking
5147

Overview

David J. Orlicky is affiliated with the University of Colorado Denver in the United States. Their research spans the fields of medicine and biochemistry, genetics, and molecular biology, with a particular focus on molecular biology, immunology, epidemiology, surgery, and oncology.

Their scientific contributions address several main topics, including:

  • Liver Disease Diagnosis and Treatment
  • Diet, Metabolism, and Disease
  • Immune Cell Function and Interaction
  • Pediatric Hepatobiliary Diseases and Treatments
  • Drug Transport and Resistance Mechanisms
  • Alcohol Consumption and Health Effects
  • Liver Diseases and Immunity

David J. Orlicky has published extensively in various venues. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Mucosal Immunology
  • Journal of Biological Chemistry
  • Hepatology
  • Chemico-Biological Interactions

Some of the recent publications authored or co-authored by Orlicky and colleagues are:

  • "Deletion of Fructokinase in the Liver or in the Intestine Reveals Differential Effects on Sugar-Induced Metabolic Dysfunction" (2020), published in Cell Metabolism
  • "Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model" (2023), published in Nature Genetics
  • "Umami-induced obesity and metabolic syndrome is mediated by nucleotide degradation and uric acid generation" (2021), published in Nature Metabolism
  • "JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome" (2020), published in Cell Reports
  • "Bile acid sequestration reverses liver injury and prevents progression of nonalcoholic steatohepatitis in Western diet-fed mice" (2020), published in Journal of Biological Chemistry

Frequent collaborators include:

  • Colin T. Shearn (16 co-authored works)
  • Rachel H. McMahan (14 co-authored works)
  • Vasilis Vasiliou (13 co-authored works)
  • Ronald J. Sokol (11 co-authored works)
  • Richard J. Johnson (10 co-authored works)

Best Publications

  • Correction: Corrigendum: Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome

    Miguel A. Lanaspa;Takuji Ishimoto;Nanxing Li;Christina Cicerchi

  • Role of p53 in silibinin-mediated inhibition of ultraviolet B radiation-induced DNA damage, inflammation and skin carcinogenesis.

    Cynthia M. Rigby;Srirupa Roy;Srirupa Roy;Gagan Deep;Gagan Deep;Ruth Guillermo-Lagae

  • CD44v6 dependence of premetastatic niche preparation by exosomes.

    Thorsten Jung;Donatello Castellana;Pamela Klingbeil;Ines Cuesta Hernández

  • High‐fat and high‐sucrose (western) diet induces steatohepatitis that is dependent on fructokinase

    Takuji Ishimoto;Miguel A. Lanaspa;Christopher J. Rivard;Carlos A. Roncal‐Jimenez

  • Expression of survivin in normal, hyperplastic, and neoplastic colonic mucosa

    Roberto Gianani;Elke Jarboe;David Orlicky;Michael Frost

  • Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease

    James L. McManaman;Elise S. Bales;David J. Orlicky;Matthew Jackman

  • High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism

    Miguel A. Lanaspa;Masanari Kuwabara;Ana Andres-Hernando;Nanxing Li

  • Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome

    Miguel A. Lanaspa;Takuji Ishimoto;Nanxing Li;Christina Cicerchi

  • C/EBPα Regulates Human Adiponectin Gene Transcription Through an Intronic Enhancer

    Liping Qiao;Paul S. MacLean;Jerome Schaack;David J. Orlicky

  • Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease

    Christopher L. Gentile;Angela M. Nivala;Jon C. Gonzales;Kyle T. Pfaffenbach

  • FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity.

    Xiaoxin X. Wang;Dong Wang;Yuhuan Luo;Komuraiah Myakala

  • Endogenous Fructose Production and Fructokinase Activation Mediate Renal Injury in Diabetic Nephropathy

    Miguel A. Lanaspa;Takuji Ishimoto;Christina Cicerchi;Yoshifuru Tamura

  • Depletion of Tumor-Associated Macrophages Slows the Growth of Chemically Induced Mouse Lung Adenocarcinomas

    Jason M. Fritz;Meredith A. Tennis;David J. Orlicky;Hao Yin

  • FPRP, a Major, Highly Stoichiometric, Highly Specific CD81- and CD9-associated Protein

    Christopher S. Stipp;David J. Orlicky;Martin E. Hemler

  • CCAAT/Enhancer-binding Protein β Deletion Reduces Adiposity, Hepatic Steatosis, and Diabetes in Leprdb/db Mice

    Jill M. Schroeder-Gloeckler;Shaikh Mizanoor Rahman;Rachel C. Janssen;Liping Qiao

  • Immunohistochemical Localization of Survivin in Benign Cervical Mucosa, Cervical Dysplasia, and Invasive Squamous Cell Carcinoma

    Michael Frost;Elke A. Jarboe;David Orlicky;Roberto Gianani

  • Aldehyde dehydrogenase 1B1: molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme.

    Dimitrios Stagos;Ying Chen;Chad Brocker;Elizabeth Donald

  • Immunohistochemical localization of the IAP protein survivin in bladder mucosa and transitional cell carcinoma.

    Rainer Lehner;M Scott Lucia;Elke A Jarboe;David Orlicky

  • Lipid droplet targeting domains of adipophilin.

    James L. McManaman;William Zabaronick;Jerome Schaack;David J. Orlicky

  • Determinants of adipophilin function in milk lipid formation and secretion

    Brandi M. Chong;Philip Reigan;Kasey D. Mayle-Combs;David J. Orlicky

Frequent Co-Authors

Vasilis Vasiliou
Vasilis Vasiliou Yale University
James L. McManaman
James L. McManaman University of Colorado Denver
Dennis R. Petersen
Dennis R. Petersen University of Colorado Anschutz Medical Campus
Rajesh Agarwal
Rajesh Agarwal University of Colorado Anschutz Medical Campus
Richard J. Johnson
Richard J. Johnson University of Colorado Denver
Carl W. White
Carl W. White University of Colorado Denver
Jerome Schaack
Jerome Schaack University of Colorado Anschutz Medical Campus
Gagan Deep
Gagan Deep Wake Forest University
Moshe Levi
Moshe Levi Georgetown University
Martin J. J. Ronis
Martin J. J. Ronis Louisiana State University Health Sciences Center New Orleans

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