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Biology and Biochemistry

D-Index
52
Citations
7731
World Ranking
16864
National Ranking
6950

Overview

Jerome Schaack is affiliated with the University of Colorado Anschutz Medical Campus in the United States. Their research spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on subfields such as Physiology, Pulmonary and Respiratory Medicine, and Surgery.

Their recent published work includes the paper titled "c-Jun, Foxo3a, and c-Myc Transcription Factors are Key Regulators of ATP-Mediated Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells †", published in 2020 in the journal Cells. This paper reflects part of their interest in molecular mechanisms underlying cardiovascular and pulmonary biology.

Jerome Schaack's primary topics of research involve:

  • Adenosine and Purinergic Signaling
  • Pulmonary Hypertension Research and Treatments
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research

The scientist has collaborated frequently with several researchers, including:

  • Derek Strassheim
  • Vijaya Karoor
  • Hala Nijmeh
  • Philip Weston
  • Martin Lapel

Publications by Jerome Schaack have appeared primarily in the journal Cells. Their research outputs contribute to understanding complex physiological and pathophysiological processes related to pulmonary and cardiovascular systems, particularly in angiogenic responses and signaling pathways relevant to endothelial cell function.

Best Publications

  • A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs.

    E Vakalopoulou;J Schaack;T Shenk

  • A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell

    Thomas C. Rich;Kent A. Fagan;Tonia E. Tse;Jerome Schaack

  • Cyclic Nucleotide–Gated Channels Colocalize with Adenylyl Cyclase in Regions of Restricted Camp Diffusion

    Thomas C. Rich;Kent A. Fagan;Hiroko Nakata;Jerome Schaack

  • Overexpression of human α-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells

    Wenbo Zhou;Marc S. Hurlbert;Jerome Schaack;Kedar N. Prasad

  • Alteration of GABAA Receptor Function Following Gene Transfer of the CLC-2 Chloride Channel

    Kevin Staley;Roderic Smith;Jerome Schaack;Christine Wilcox

  • In Vivo Assessment of Local Phosphodiesterase Activity Using Tailored Cyclic Nucleotide–Gated Channels as Camp Sensors

    Thomas C. Rich;Tonia E. Tse;Joyce G. Rohan;Jerome Schaack

  • An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics.

    Debbie Willoughby;Wei Wong;Jerome Schaack;John D Scott

  • Adenovirus terminal protein mediates both nuclear matrix association and efficient transcription of adenovirus DNA.

    J Schaack;W Y Ho;P Freimuth;T Shenk

  • C/EBPα Regulates Human Adiponectin Gene Transcription Through an Intronic Enhancer

    Liping Qiao;Paul S. MacLean;Jerome Schaack;David J. Orlicky

  • Overexpression of human α-synuclein causes dopamine neuron death in primary human mesencephalic culture

    Wenbo Zhou;Jerome Schaack;W.Michael Zawada;Curt R. Freed

  • Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH.

    Ishtiaq Qadri;Joan W. Conaway;Ronald C. Conaway;Jerome Schaack

  • Induced oxidative stress and activated expression of manganese superoxide dismutase during hepatitis C virus replication: role of JNK, p38 MAPK and AP-1.

    Ishtiaq Qadri;Mieko Iwahashi;Juan M Capasso;Matthew W Hopken

  • Oxidative Inactivation of Mitochondrial Aconitase Results in Iron and H2O2-Mediated Neurotoxicity in Rat Primary Mesencephalic Cultures

    David Cantu;Jerome Schaack;Manisha Patel

  • cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration.

    Dwight J. Klemm;Dwight J. Klemm;Peter A. Watson;Maria G. Frid;Edward C. Dempsey;Edward C. Dempsey

  • Novel Mechanism for Gonadotropin-Releasing Hormone Neuronal Migration Involving Gas6/Ark Signaling to p38 Mitogen-Activated Protein Kinase

    Melissa P. Allen;Daniel A. Linseman;Hiroshi Udo;Mei Xu

  • Adenosine A2A receptor is a unique angiogenic target of HIF-2α in pulmonary endothelial cells

    Aftab Ahmad;Shama Ahmad;Louise Glover;Stacy M. Miller

  • 3D Models of Epithelial-Mesenchymal Transition in Breast Cancer Metastasis: High-Throughput Screening Assay Development, Validation, and Pilot Screen

    Qun Li;Chaoyu Chen;Amit Kapadia;Qiong Zhou

  • Adiponectin Inhibits Lipolysis in Mouse Adipocytes

    Liping Qiao;Brice Kinney;Jerome Schaack;Jianhua Shao

  • Efficient selection of recombinant adenoviruses by vectors that express beta-galactosidase.

    J. Schaack;S. Langer;Xiaoling Guo

  • Regulation of a Ca2+-sensitive Adenylyl Cyclase in an Excitable Cell: ROLE OF VOLTAGE-GATED VERSUS CAPACITATIVE Ca2+ ENTRY

    Kent A. Fagan;Robert A. Graf;Shawna Tolman;Jerome Schaack

Frequent Co-Authors

David J. Orlicky
David J. Orlicky University of Colorado Denver
Jaime F. Modiano
Jaime F. Modiano University of Minnesota
Dieter Söll
Dieter Söll Yale University
Thomas Shenk
Thomas Shenk Princeton University
James DeGregori
James DeGregori University of Colorado Anschutz Medical Campus
Dermot M. F. Cooper
Dermot M. F. Cooper University of Cambridge
James L. McManaman
James L. McManaman University of Colorado Denver
Carl W. White
Carl W. White University of Colorado Denver
Aleem Siddiqui
Aleem Siddiqui University of California, San Diego
Curt R. Freed
Curt R. Freed University of Colorado Denver

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