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D-Index
69
Citations
15432
World Ranking
2655
National Ranking
1249

Overview

Ilo E. Leppik is affiliated with the University of Minnesota in the United States and has a research focus primarily in the fields of medicine and neuroscience. Their extensive work covers multiple subfields including psychiatry and mental health, pediatrics, perinatology and child health, cellular and molecular neuroscience, pharmacology, and cognitive neuroscience.

Their research contributions encompass a broad range of topics centered on epilepsy research and treatment, pharmacological effects and toxicity studies, neuroscience and neuropharmacology research, antibiotics pharmacokinetics and efficacy, EEG and brain-computer interfaces, drug transport and resistance mechanisms, as well as schizophrenia research and treatment.

Recent notable papers authored or co-authored by Leppik include:

  • The epidemiology of epilepsy in older adults: A narrative review by the ILAE Task Force on Epilepsy in the Elderly (2023, Epilepsia)
  • Management of epilepsy in older adults: A critical review by the ILAE Task Force on Epilepsy in the elderly (2022, Epilepsia)
  • Severity of Topiramate-Related Working Memory Impairment Is Modulated by Plasma Concentration and Working Memory Capacity (2020, The Journal of Clinical Pharmacology)
  • Intravenous and Intramuscular Allopregnanolone for Early Treatment of Status Epilepticus: Pharmacokinetics, Pharmacodynamics, and Safety in Dogs (2021, Journal of Pharmacology and Experimental Therapeutics)
  • New Onset (Incidence) of Epilepsy and Seizures in Nursing Home Residents (2022, Journal of the American Medical Directors Association)

Leppik frequently publishes in several journals, with the most common venues being:

  • Epilepsia
  • Journal of the American Medical Directors Association
  • Neurology
  • The Journal of Clinical Pharmacology
  • Current Opinion in Neurology

Key collaborators frequently working alongside Leppik include Angela K. Birnbaum, Patrick Kwan, Rebecca O'Dwyer, Susan E. Marino, and Robert Wechsler. These co-authors have contributed collectively to multiple projects spanning epilepsy and pharmacological research.

Leppik's research methodology often integrates clinical and pharmacological approaches to better understand neurological disorders and treatment effects. The work spans both adult and pediatric populations, with particular attention given to epilepsy in elderly populations and the pharmacokinetic factors influencing drug efficacy and side effects.

Best Publications

  • Antiepileptic drugs—best practice guidelines for therapeutic drug monitoring: A position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic Strategies

    Philip N. Patsalos;David J. Berry;Blaise F. D. Bourgeois;James C. Cloyd

  • Levetiracetam for partial seizures Results of a double-blind, randomized clinical trial

    Cereghino Jj;Biton;Abou-Khalil B;Dreifuss F

  • Incidence and risk factors in sudden unexpected death in epilepsy: A prospective cohort study

    Thaddeus S. Walczak;I. E. Leppik;M. D'Amelio;J. Rarick

  • Double-blind study of lorazepam and diazepam in status epilepticus.

    Ilo E Leppik;A. T. Derivan;R. W. Homan;J. Walker

  • Lamotrigine clearance during pregnancy

    T. A. Tran;I. E. Leppik;K. Blesi;S. T. Sathanandan

  • Randomized controlled trial of zonisamide for the treatment of refractory partial-onset seizures.

    E. Faught;R. Ayala;G. G. Montouris;I. E. Leppik

  • Gabapentin as add-on therapy in refractory partial epilepsy: A double-blind, placebo-controlled, parallel-group study

    Michael J. McLean;R. E. Ramsay;Ilo E Leppik;A. J. Rowan

  • Hyponatremia from oxcarbazepine and carbamazepine

    Xiaoming Dong;Ilo E. Leppik;James White;John Rarick

  • Felbamate for partial seizures: results of a controlled clinical trial.

    I. E. Leppik;F. E. Dreifuss;G. W. Pledger;N. M. Graves

  • Intravenous phenytoin: Clinical and pharmacokinetic aspects

    Ronald E. Cranford;Ilo E. Leppik;Barbara Patrick;Charles B. Anderson

  • Antiepileptic drug development

    Jacqueline A. French;Marc A. Dichter;Ilo E. Leppik

  • Discontinuation of levetiracetam because of behavioral side effects A case-control study

    J. R. White;T. S. Walczak;I. E. Leppik;J. Rarick

  • Efficacy and safety of zonisamide: results of a multicenter study

    Ilo E Leppik;L. J. Willmore;R. W. Homan;G. Fromm

  • Neurologic prognosis after cardiopulmonary arrest III. Seizure activity

    B. D. Snyder;W. A. Hauser;R. B. Loewenson;I. E. Leppik

  • Felbamate A double‐blind controlled trial in patients undergoing presurgical evaluation of partial seizures

    Bourgeois Bourgeois;I. E. Leppik;J. C. Sackellares;K. Laxer

  • Tiagabine for Complex Partial Seizures: A Randomized, Add-on, Dose-Response Trial

    Basim M. Uthman;A. James Rowan;Peter A. Ahmann;Ilo E. Leppik

  • Salivary levels of anticonvulsants: A practical approach to drug monitoring

    John J. McAULIFFE;Allan L. Sherwin;Ilo E. Leppik;Shirley A. Fayle

  • COST OF REFRACTORY EPILEPSY IN ADULTS IN THE USA

    Miranda I. Murray;Michael T. Halpern;Ilo E. Leppik

  • Bilateral central macrogyria: epilepsy, pseudobulbar palsy, and mental retardation--a recognizable neuronal migration disorder.

    Ruben Kuzniecky;Frederick Andermann;Donatella Tampieri;Denis Melanson

  • Epilepsy in the elderly.

    Ilo E. Leppik

  • Three new drugs for epilepsy: levetiracetam, oxcarbazepine, and zonisamide.

    Ilo E. Leppik

  • Gabapentin as add-on therapy in refractory partial epilepsy

    Michael J. McLean;R. E. Ramsay;Ilo E Leppik;A. J. Rowan

Frequent Co-Authors

Jacqueline A. French
Jacqueline A. French New York University
Page B. Pennell
Page B. Pennell University of Pittsburgh
Thaddeus S. Walczak
Thaddeus S. Walczak University of Minnesota
Steven C. Schachter
Steven C. Schachter Beth Israel Deaconess Medical Center
Edward Faught
Edward Faught Emory University
Gregory K. Bergey
Gregory K. Bergey Johns Hopkins University School of Medicine
Basim M. Uthman
Basim M. Uthman Weill Cornell Medical College in Qatar
John M. Pellock
John M. Pellock Virginia Commonwealth University
Fritz E. Dreifuss
Fritz E. Dreifuss University of Virginia
Stephen S. Rich
Stephen S. Rich University of Virginia

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