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Immunology

D-Index
54
Citations
8889
World Ranking
3910
National Ranking
1791

Overview

David Rekosh is affiliated with the University of Virginia in the United States. Their research focuses on several areas within medicine and the biological sciences, particularly emphasizing HIV research, molecular biology, and virology. The body of work includes contributions to infectious diseases, RNA mechanisms, and immunology.

Rekosh's research encompasses the following main fields of study:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology
  • Immunology and Microbiology

Their work extends into notable subfields such as:

  • Infectious Diseases
  • Molecular Biology
  • Virology
  • Epidemiology
  • Plant Science

Among their primary topics of investigation are:

  • HIV Research and Treatment
  • HIV/AIDS drug development and treatment
  • Cytomegalovirus and herpesvirus research
  • Chromosomal and Genetic Variations
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • RNA modifications and cancer

Several recent papers showcase the scope of Rekosh's scholarly output. These include:

  • "Intron retention and its impact on gene expression and protein diversity: A review and a practical guide," 2020, Wiley Interdisciplinary Reviews - RNA
  • "Upregulation of human endogenous retrovirus-K (HML-2) mRNAs in hepatoblastoma: Identification of potential new immunotherapeutic targets and biomarkers," 2020, Journal of Pediatric Surgery
  • "HIV-1 Rev-RRE functional activity in primary isolates is highly dependent on minimal context-dependent changes in Rev," 2022, Scientific Reports
  • "Sequence and Functional Variation in the HIV-1 Rev Regulatory Axis," 2020, Current HIV Research
  • "Development of a pseudovirus assay and evaluation to screen natural products for inhibition of HIV-1 subtype C reverse transcriptase," 2020, Journal of Ethnopharmacology

Rekosh often collaborates with a group of frequent co-authors, including:

  • Marie-Louise Hammarskjöld
  • Patrick Jackson
  • Godfrey Dzhivhuho
  • David F. Grabski
  • Jordan Holsey

Their research has been published repeatedly in venues that include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Wiley Interdisciplinary Reviews - RNA
  • Scientific Reports
  • Current HIV Research
  • Journal of Ethnopharmacology

Best Publications

  • Identification of a protein linked to the ends of adenovirus DNA

    D.M.K. Rekosh;W.C. Russell;A.J.D. Bellet;A.J. Robinson

  • A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent.

    Molly Bray;Susan Prasad;John W. Dubay;Eric Hunter

  • Regulation of human immunodeficiency virus env expression by the rev gene product.

    M L Hammarskjöld;J Heimer;B Hammarskjöld;I Sangwan

  • The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway.

    Amy E. Pasquinelli;Robert K. Ernst;Elsebet Lund;Christian Grimm

  • Human immunodeficiency virus type 1 Pr55gag and Pr160gag-pol expressed from a simian virus 40 late replacement vector are efficiently processed and assembled into viruslike particles.

    A J Smith;M I Cho;M L Hammarskjöld;D Rekosh

  • Role of Pr160gag-pol in mediating the selective incorporation of tRNA(Lys) into human immunodeficiency virus type 1 particles.

    Johnson Mak;Min Jiang;Mark A. Wainberg;Marie-Louise Hammarskjöld

  • A structured retroviral RNA element that mediates nucleocytoplasmic export of intron-containing RNA.

    Robert K. Ernst;Molly Bray;David Rekosh;Marie Louise Hammarskjöld

  • Requirements for incorporation of Pr160gag-pol from human immunodeficiency virus type 1 into virus-like particles.

    A. J. Smith;Narasimhachar Srinivasakumar;M.-L. Hammarskjöld;D. Rekosh

  • U1 small nuclear RNA plays a direct role in the formation of a rev-regulated human immunodeficiency virus env mRNA that remains unspliced.

    Xiaobin Lu;Jessica Heimer;David Rekosh;Marie-Louise Hammarskjold

  • An intron with a constitutive transport element is retained in a Tap messenger RNA

    Ying Li;Yeou-Cherng Bor;Yukiko Misawa;Yuming Xue

  • The effect of viral regulatory protein expression on gene delivery by human immunodeficiency virus type 1 vectors produced in stable packaging cell lines.

    Narasimhachar Srinivasakumar;Nathalie Chazal;C. Helga-Maria;Susan Prasad

  • Characterization of deletion mutations in the capsid region of human immunodeficiency virus type 1 that affect particle formation and Gag-Pol precursor incorporation.

    Narasimhachar Srinivasakumar;M.-L. Hammarskjold;D. Rekosh

  • Chondrocyte transplantation into articular cartilage defects with use of calcium alginate: the fate of the cells.

    Cay M. Mierisch;Heather A. Wilson;Maria A. Turner;Todd A. Milbrandt

  • Effect of pactamycin on synthesis of poliovirus proteins: a method for genetic mapping.

    Robert Taber;David Rekosh;David Baltimore

  • Human Immunodeficiency Virus Type 1 Particles Pseudotyped with Envelope Proteins That Fuse at Low pH No Longer Require Nef for Optimal Infectivity

    Nathalie Chazal;Gregory Singer;Christopher Aiken;Marie-Louise Hammarskjöld

  • NXT1 (p15) is a crucial cellular cofactor in TAP-dependent export of intron-containing RNA in mammalian cells.

    Brian W. Guzik;Lyne Levesque;Susan Prasad;Yeou-Cherng Bor

  • Identification of a cis-acting element in human immunodeficiency virus type 2 (HIV-2) that is responsive to the HIV-1 rev and human T-cell leukemia virus types I and II rex proteins.

    N Lewis;J Williams;D Rekosh;M L Hammarskjöld

  • Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.

    John H. Coyle;Brian W. Guzik;Yeou-Cherng Bor;Li Jin

  • Tap and NXT promote translation of unspliced mRNA

    Li Jin;Brian W. Guzik;Yeou-cherng Bor;David Rekosh

  • Probing the HIV-1 genomic RNA trafficking pathway and dimerization by genetic recombination and single virion analyses.

    Michael D. Moore;Olga A. Nikolaitchik;Jianbo Chen;Marie-Louise Hammarskjöld

  • The Wilms’ tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron

    Yeou-cherng Bor;Jennifer Swartz;Avril Morrison;David Rekosh

Frequent Co-Authors

Marie-Louise Hammarskjold
Marie-Louise Hammarskjold University of Virginia
Philip T. LoVerde
Philip T. LoVerde The University of Texas Health Science Center at San Antonio
Kathryn Anastos
Kathryn Anastos Albert Einstein College of Medicine
Eric Hunter
Eric Hunter Emory University
Robert K. Ernst
Robert K. Ernst University of Maryland, Baltimore
Bryce M. Paschal
Bryce M. Paschal University of Virginia
Leon G. Epstein
Leon G. Epstein Northwestern University
David Baltimore
David Baltimore California Institute of Technology
Kuan-Teh Jeang
Kuan-Teh Jeang National Institutes of Health
Ben E. Black
Ben E. Black University of Pennsylvania

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