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Christian Bailly

Christian Bailly

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Chemistry
France
2025

D-Index & Metrics

Chemistry

D-Index
84
Citations
22090
World Ranking
2860
National Ranking
71

Research.com Recognitions

  • 2025 - Research.com Chemistry in France Leader Award
  • 2022 - Research.com Chemistry in France Leader Award

Overview

Christian Bailly is affiliated with the University of Lille in France and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work covers a range of subfields including molecular biology, pharmacology, organic chemistry, oncology, and plant science.

The scientist's research focuses significantly on natural product bioactivities and synthesis, phytochemical compounds' biological activities, and microbial natural products and biosynthesis. Additional topics of interest include computational drug discovery methods, plant biochemistry and biosynthesis, pharmacological effects of natural compounds, and cancer immunotherapy and biomarkers.

Bailly has published numerous papers in well-known scientific venues. Frequent publication outlets include Biochemical Pharmacology, Molecules, Cancers, European Journal of Pharmacology, and Natural Products and Bioprospecting.

Recent papers authored by Bailly include:

  • Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome? (2020, Pharmacology & Therapeutics)
  • Combined cytotoxic chemotherapy and immunotherapy of cancer: modern times (2020, NAR Cancer)
  • Soluble Programmed Death Ligand-1 (sPD-L1): A Pool of Circulating Proteins Implicated in Health and Diseases (2021, Cancers)
  • Molecular and cellular basis of the anticancer activity of the prenylated flavonoid icaritin in hepatocellular carcinoma (2020, Chemico-Biological Interactions)
  • Atractylenolides, essential components of Atractylodes-based traditional herbal medicines: Antioxidant, anti-inflammatory and anticancer properties (2020, European Journal of Pharmacology)

The research collaborations of Christian Bailly include frequent co-authorship with Gérard Vergoten, Xavier Thuru, Romain Magnez, Bruno Quesnel, and Jean-François Goossens.

Best Publications

  • Strategies and challenges for the next generation of therapeutic antibodies

    Alain Beck;Thierry Wurch;Christian Bailly;Nathalie Corvaia

  • DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata.

    Yves Pommier;Glenda Kohlhagen;Christian Bailly;Michael Waring

  • Sequence-specific DNA minor groove binders. Design and synthesis of netropsin and distamycin analogues.

    Christian Bailly;Jonathan B. Chaires

  • Topoisomerase I Poisons and Suppressors as Anticancer Drugs

    Christian Bailly

  • Lamellarins, from A to Z: a family of anticancer marine pyrrole alkaloids.

    Christian Bailly

  • Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome?

    Christian Bailly;Gérard Vergoten

  • Molecular determinants of topoisomerase I poisoning by lamellarins: comparison with camptothecin and structure-activity relationships.

    Esther Marco;William Laine;Christelle Tardy;Amélie Lansiaux

  • The DNA intercalating alkaloid cryptolepine interferes with topoisomerase II and inhibits primarily DNA synthesis in B16 melanoma cells.

    K Bonjean;M C De Pauw-Gillet;M P Defresne;P Colson

  • Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production.

    Murielle Mimeault;Nicole Pommery;Nicole Wattez;Christian Bailly

  • Drugs targeting mitochondrial functions to control tumor cell growth.

    Nathalie Dias;Christian Bailly

  • Combined cytotoxic chemotherapy and immunotherapy of cancer: modern times

    Christian Bailly;Xavier Thuru;Bruno Quesnel

  • Selective recognition of g-quadruplex telomeric DNA by a bis(quinacridine) macrocycle

    Marie-Paule Teulade-Fichou;Carolina Carrasco;Lionel Guittat;Christian Bailly

  • Mitochondrial proliferation during apoptosis induced by anticancer agents: effects of doxorubicin and mitoxantrone on cancer and cardiac cells.

    Jérôme Kluza;Philippe Marchetti;Miguel-Angel Gallego;Steve Lancel

  • Cytotoxic and antitumor potentialities of aporphinoid alkaloids

    Caroline Stevigny;Christian Bailly;Joëlle Quetin-Leclercq

  • Cytotoxicity and cell cycle effects of the plant alkaloids cryptolepine and neocryptolepine: relation to drug-induced apoptosis

    Laurent Dassonneville;Amélie Lansiaux;Aurélie Wattelet;Nicole Wattez

  • Oxidation of CuII to CuIII, Free Radical Production, and DNA Cleavage by Hydroxy-salen−Copper Complexes. Isomeric Effects Studied by ESR and Electrochemistry

    Eric Lamour;Sylvain Routier;Jean-Luc Bernier;Jean-Pierre Catteau

  • Synthesis, cytotoxicity, and antiplasmodial and antitrypanosomal activity of new neocryptolepine derivatives.

    Tim H. M. Jonckers;Sabine van Miert;Kanyanga Cimanga;Christian Bailly

  • Anticancer Properties of Lamellarins

    Unknown

  • Triptolide is an inhibitor of RNA polymerase I and II–dependent transcription leading predominantly to down-regulation of short-lived mRNA

    Stéphane Vispé;Luc DeVries;Laurent Créancier;Jérome Besse

  • Cancer Cell Mitochondria Are Direct Proapoptotic Targets for the Marine Antitumor Drug Lamellarin D

    Jérôme Kluza;Miguel-Angel Gallego;Anne Loyens;Jean-Claude Beauvillain

  • Polo-like kinase 1 is overexpressed in acute myeloid leukemia and its inhibition preferentially targets the proliferation of leukemic cells.

    Annelies G. Renner;Cédric Dos Santos;Christian Recher;Christian Bailly

  • Synthesis of a Functionalized Salen−Copper Complex and Its Interaction with DNA

    Sylvain Routier;Jean-Luc Bernier;Michael J. Waring;Pierre Colson

  • DNA Cleavage by Topoisomerase I in the Presence of Indolocarbazole Derivatives of Rebeccamycin

    Christian Bailly;Jean-François Riou;Pierre Colson;Claude Houssier

Frequent Co-Authors

Michael J. Waring
Michael J. Waring University of Cambridge
David W. Boykin
David W. Boykin Georgia State University
W. David Wilson
W. David Wilson Georgia State University
Farial A. Tanious
Farial A. Tanious Georgia State University
Jonathan B. Chaires
Jonathan B. Chaires University of Louisville
Hervé Vezin
Hervé Vezin University of Lille
Jean-François Riou
Jean-François Riou French National Museum of Natural History
Marie-Paule Teulade-Fichou
Marie-Paule Teulade-Fichou University of Paris-Saclay
Christophe Marchand
Christophe Marchand National Institutes of Health

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