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Yutaka Seino

Yutaka Seino

D-Index & Metrics

Medicine

D-Index
99
Citations
38257
World Ranking
8557
National Ranking
223

Overview

Yutaka Seino is affiliated with Kyoto University in Japan and has contributed extensively to the field of medicine with a particular focus on endocrinology, diabetes, and metabolism. Their research work spans various subfields including surgery, molecular biology, physiology, and endocrine and autonomic systems, with a primary emphasis on diabetes treatment and management.

The scientist's research centers around critical topics such as:

  • Diabetes Treatment and Management
  • Metabolism, Diabetes, and Cancer
  • Diabetes Management and Research
  • Pancreatic function and diabetes
  • Regulation of Appetite and Obesity
  • Diet and metabolism studies
  • Nutrition and Health in Aging

Seino's work is frequently published in key journals, contributing notably to:

  • Journal of Diabetes Investigation
  • Diabetes Obesity and Metabolism
  • Diabetes
  • Nutrients
  • Diabetes Research and Clinical Practice

Among their recent scholarly papers are:

  • Dose-response, efficacy, and safety of oral semaglutide monotherapy in Japanese patients with type 2 diabetes (PIONEER 9): a 52-week, phase 2/3a, randomised, controlled trial, 2020, The Lancet Diabetes & Endocrinology
  • Efficacy and safety of tirzepatide monotherapy compared with dulaglutide in Japanese patients with type 2 diabetes (SURPASS J-mono): a double-blind, multicentre, randomised, phase 3 trial, 2022, The Lancet Diabetes & Endocrinology
  • Efficacy and safety of the sodium-glucose co-transporter-2 inhibitor empagliflozin in elderly Japanese adults (≥65 years) with type 2 diabetes: A randomized, double-blind, placebo-controlled, 52-week clinical trial (EMPA-ELDERLY), 2023, Diabetes Obesity and Metabolism
  • Cardiovascular and renal effectiveness of empagliflozin in routine care in East Asia: Results from the EMPRISE East Asia study, 2020, Endocrinology Diabetes & Metabolism
  • Effects of glucagon-like peptide-1 receptor agonists on secretions of insulin and glucagon and gastric emptying in Japanese individuals with type 2 diabetes: A prospective, observational study, 2021, Journal of Diabetes Investigation

The scientist often collaborates with other researchers, with frequent co-authors including:

  • Daisuke Yabe
  • Yuichiro Yamada
  • Yoshiyuki Hamamoto
  • Hitoshi Kuwata
  • Takashi Kadowaki

Best Publications

  • Report of the Committee on the Classification and Diagnostic Criteria of Diabetes Mellitus

    Yutaka Seino;Kishio Nanjo;Naoko Tajima;Takashi Kadowaki

  • Inhibition of gastric inhibitory polypeptide signaling prevents obesity.

    Kazumasa Miyawaki;Yuichiro Yamada;Nobuhiro Ban;Yu Ihara

  • Report of the Committee on the classification and diagnostic criteria of diabetes mellitus

    Takeshi Kuzuya;Shoichi Nakagawa;Jo Satoh;Yasunori Kanazawa

  • Report of the Committee on the classification and diagnostic criteria of diabetes mellitus : The Committee of the Japan Diabetes Society on the diagnostic criteria of diabetes mellitus

    Yutaka Seino;Kishio Nanjo;Naoko Tajima;Takashi Kadowaki

  • Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

    Kazuki Yasuda;Kazuaki Miyake;Yukio Horikawa;Kazuo Hara

  • Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.

    Y Ihara;S Toyokuni;K Uchida;H Odaka

  • The Lancet Commission on diabetes: using data to transform diabetes care and patient lives

    Juliana C N Chan;Lee-Ling Lim;Nicholas J Wareham;Jonathan E Shaw

  • Over-expression of facilitative glucose transporter genes in human cancer.

    Taizo Yamamoto;Yutaka Seino;Hirofumi Fukumoto;Gyohan Koh

  • Cloning and Functional Characterization of a Novel ATP-sensitive Potassium Channel Ubiquitously Expressed in Rat Tissues, including Pancreatic Islets, Pituitary, Skeletal Muscle, and Heart

    Nobuya Inagaki;Yoshiyuki Tsuura;Noriyuki Namba;Kazuhiro Masuda

  • Sequence, tissue distribution, and chromosomal localization of mRNA encoding a human glucose transporter-like protein.

    Hirofumi Fukumoto;Susumu Seino;Hiroo Imura;Yutaka Seino

  • Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase.

    Y. Yamada;T. Reisine;S. F. Law;Yu Ihara

  • Insulin secretion capacity in the development from normal glucose tolerance to type 2 diabetes.

    Mitsuo Fukushima;Haruhiko Suzuki;Yutaka Seino

  • Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure.

    Tanya Hansotia;Adriano Maida;Grace Flock;Yuichiro Yamada

  • Identification of somatostatin receptor subtypes and an implication for the efficacy of somatostatin analogue SMS 201-995 in treatment of human endocrine tumors.

    A Kubota;Y Yamada;S Kagimoto;A Shimatsu

  • Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors

    Tanya Hansotia;Laurie L. Baggio;Dominique Delmeire;Simon A. Hinke

  • The protective roles of GLP-1R signaling in diabetic nephropathy: possible mechanism and therapeutic potential

    Hiroki Fujita;Tsukasa Morii;Hiromi Fujishima;Takehiro Sato

  • The murine glucagon-like peptide-1 receptor is essential for control of bone resorption

    Chizumi Yamada;Yuichiro Yamada;Katsushi Tsukiyama;Kotaro Yamada

  • Randomized, double-blind, placebo-controlled trial of the once-daily GLP-1 receptor agonist lixisenatide in Asian patients with type 2 diabetes insufficiently controlled on basal insulin with or without a sulfonylurea (GetGoal-L-Asia)

    Y Seino;K W Min;E Niemoeller;A Takami

  • Cloning, Functional Expression and Pharmacological Characterization of a Fourth (hSSTR4) and a Fifth (hSSTR5) Human Somatostatin Receptor Subtype

    Y. Yamada;S. Kagimoto;A. Kubota;K. Yasuda

  • The Pro12→Ala Substitution in PPAR-γ Is Associated With Resistance to Development of Diabetes in the General Population: Possible Involvement in Impairment of Insulin Secretion in Individuals With Type 2 Diabetes

    Hiroyuki Mori;Hiroshi Ikegami;Yoshihiko Kawaguchi;Susumu Seino

Frequent Co-Authors

Hiroo Imura
Hiroo Imura Kyoto University
Nobuya Inagaki
Nobuya Inagaki Kyoto University
Susumu Seino
Susumu Seino Kobe University
Takashi Kadowaki
Takashi Kadowaki Toranomon Hospital
Tsutomu Chiba
Tsutomu Chiba Kyoto University
Minoru Horie
Minoru Horie Shiga University of Medical Science
Daniel J. Drucker
Daniel J. Drucker Lunenfeld-Tanenbaum Research Institute
Bo Ahrén
Bo Ahrén Lund University
Noboru Yanaihara
Noboru Yanaihara University of Shizuoka
Shinya Toyokuni
Shinya Toyokuni Nagoya University

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