Tomohiko Ogawa

Overview

Best Publications

• Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product.

  Katsuaki Hoshino;Osamu Takeuchi;Taro Kawai;Hideki Sanjo

  4717
  Citations

• Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.

  Osamu Takeuchi;Katsuaki Hoshino;Taro Kawai;Hideki Sanjo

  4277
  Citations

• Unresponsiveness of MyD88-Deficient Mice to Endotoxin

  Taro Kawai;Osamu Adachi;Tomohiko Ogawa;Kiyoshi Takeda

  2420
  Citations

• Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades.

  Osamu Takeuchi;Kiyoshi Takeda;Katsuaki Hoshino;Osamu Adachi

  464
  Citations

• Gene Expressions of Toll-Like Receptor 2, But Not Toll-Like Receptor 4, Is Induced by LPS and Inflammatory Cytokines in Mouse Macrophages

  Tetsuya Matsuguchi;Tipayaratn Musikacharoen;Tomohiko Ogawa;Yasunobu Yoshikai

  414
  Citations

• Synthetic lipid A with endotoxic and related biological activities comparable to those of a natural lipid A from an Escherichia coli re-mutant.

  S Kotani;H Takada;M Tsujimoto;T Ogawa

  338
  Citations

• Relationship between Structures and Biological Activities of Mycoplasmal Diacylated Lipopeptides and Their Recognition by Toll-Like Receptors 2 and 6

  Tsugumi Okusawa;Mari Fujita;Jun Ichiro Nakamura;Takeshi Into

  221
  Citations

• Expression of toll-like receptor 2 on gamma delta T cells bearing invariant V gamma 6/V delta 1 induced by Escherichia coli infection in mice.

  Yasuji Mokuno;Tetsuya Matsuguchi;Manabu Takano;Hitoshi Nishimura

  211
  Citations

• Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4- and myeloid differentiation factor 88-dependent signaling pathway.

  Tomohiko Ogawa;Yasuyuki Asai;Masahito Hashimoto;Osamu Takeuchi

  188
  Citations

• Separation and structural analysis of lipoprotein in a lipopolysaccharide preparation from Porphyromonas gingivalis.

  Masahito Hashimoto;Yasuyuki Asai;Tomohiko Ogawa

  174
  Citations

• Antimicrobial Activity of Perilla Seed Polyphenols against Oral Pathogenic Bacteria

  Hiroyo Yamamoto;Tomohiko Ogawa

  168
  Citations

• Increase in tumor necrosis factor alpha- and interleukin-6-secreting cells in peripheral blood mononuclear cells from subjects infected with Mycobacterium tuberculosis.

  T Ogawa;H Uchida;Y Kusumoto;Y Mori

  145
  Citations

• Chemical structure and immunobiological activity of Porphyromonas gingivalis lipid A.

  Tomohiko Ogawa;Yasuyuki Asai;Yutaka Makimura;Riyoko Tamai

  137
  Citations

• Bacterial fimbriae activate human peripheral blood monocytes utilizing TLR2, CD14 and CD11a/CD18 as cellular receptors.

  Tomohiko Ogawa;Yasuyuki Asai;Masahito Hashimoto;Hiroshi Uchida

  135
  Citations

• Immunobiological activities of synthetic peptide segments of fimbrial protein from Porphyromonas gingivalis.

  Tomohiko Ogawa;Yutaka Kusumoto;Hiroshi Uchida;Shigeru Nagashima

  107
  Citations

• Binding of Porphyromonas gingivalis fimbriae to Treponema denticola dentilisin.

  Masahito Hashimoto;Shuji Ogawa;Yasuyuki Asai;Yoshiaki Takai

  104
  Citations

• Porphyromonas gingivalis fimbriae and their synthetic peptides induce proinflammatory cytokines in human peripheral blood monocyte cultures

  Tomohiko Ogawa;Hiroshi Uchida;Shigeyuki Hamada

  100
  Citations

• Immunobiological activities of chemically defined lipid A from lipopolysaccharides of Porphyromonas gingivalis.

  Tomohiko Ogawa;Hiroshi Uchida;Kayoko Amino

  98
  Citations

• Immunobiological activities of chemically defined lipid A from Helicobacter pylori LPS in comparison with Porphyromonas gingivalis lipid A and Escherichia coli-type synthetic lipid A (compound 506)

  Tomohiko Ogawa;Yasuo Suda;Wataru Kashihara;Tomoko Hayashi

  98
  Citations

• Natural killer cell activities of synbiotic Lactobacillus casei ssp. casei in conjunction with dextran

  T Ogawa;Y Asai;R Tamai;Y Makimura

  96
  Citations