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Medicine

D-Index
71
Citations
22834
World Ranking
19955
National Ranking
674

Overview

Sylvie Castaigne is affiliated with Versailles Saint-Quentin-en-Yvelines University in France. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology.

Their main subfields of study include Hematology, Molecular Biology, Epidemiology, Public Health, Environmental and Occupational Health, and Neurology.

Castaigne's work focuses extensively on Acute Myeloid Leukemia Research, covering topics such as Epigenetics and DNA Methylation, Acute Lymphoblastic Leukemia research, Retinoids in leukemia and cellular processes, Neuroblastoma Research and Treatments, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, and Histone Deacetylase Inhibitors Research.

Among recent papers authored or co-authored by Castaigne are:

  • Vitamin D Receptor Controls Cell Stemness in Acute Myeloid Leukemia and in Normal Bone Marrow, 2020, Cell Reports
  • Biomarkers of Gemtuzumab Ozogamicin Response for Acute Myeloid Leukemia Treatment, 2020, International Journal of Molecular Sciences
  • Early detection of WT1 measurable residual disease identifies high-risk patients, independent of transplantation in AML, 2021, Blood Advances
  • Outcomes following hematopoietic stem cell transplantation in patients treated with standard chemotherapy with or without gemtuzumab ozogamicin for acute myeloid leukemia, 2021, Bone Marrow Transplantation
  • A transcriptomic continuum of differentiation arrest identifies myeloid interface acute leukemias with poor prognosis, 2020, Leukemia

The most frequent publication venues for Castaigne's research include Blood, Cell Reports, International Journal of Molecular Sciences, Blood Advances, and Bone Marrow Transplantation.

Frequent co-authors collaborating with Castaigne are:

  • Hervé Dombret
  • Claude Preudhomme
  • Juliette Lambert
  • Cécile Pautas
  • Sylvain Chantepie

Best Publications

  • All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results.

    Sylvie Castaigne;Christine Chomienne;Marie Therese Daniel;Paola Ballerini

  • Long-term outcome of patients in the LNH-98.5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: a study by the Groupe d'Etudes des Lymphomes de l'Adulte

    Bertrand Coiffier;Catherine Thieblemont;Eric Van Den Neste;Gérard Lepeu

  • A Randomized Comparison of All Transretinoic Acid (ATRA) Followed by Chemotherapy and ATRA Plus Chemotherapy and the Role of Maintenance Therapy in Newly Diagnosed Acute Promyelocytic Leukemia

    Pierre Fenaux;Claude Chastang;Sylvie Chevret;Miguel Sanz

  • Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study

    Sylvie Castaigne;Cécile Pautas;Christine Terré;Emmanuel Raffoux

  • Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: A meta-analysis of individual patient data from randomised controlled trials

    Robert Kerrin Hills;Sylvie Castaigne;Frederick R. Appelbaum;Jacques Delaunay

  • Effect of all transretinoic acid in newly diagnosed acute promyelocytic leukemia. Results of a multicenter randomized trial. European APL 91 Group

    P Fenaux;MC Le Deley;S Castaigne;E Archimbaud

  • Favorable prognostic significance of CEBPA mutations in patients with de novo acute myeloid leukemia: a study from the Acute Leukemia French Association (ALFA).

    Claude Preudhomme;Christophe Sagot;Nicolas Boissel;Jean-Michel Cayuela

  • Attenuated immunochemotherapy regimen (R-miniCHOP) in elderly patients older than 80 years with diffuse large B-cell lymphoma: a multicentre, single-arm, phase 2 trial.

    Frédéric Peyrade;Fabrice Jardin;Catherine Thieblemont;Antoine Thyss

  • All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship

    Christine Chomienne;Paola Ballerini;Nicole Balitrand;Marie Therese Daniel

  • All-trans-retinoic acid as a differentiating agent in the treatment of acute promyelocytic leukemia.

    L Degos;H Dombret;C Chomienne;M T Daniel

  • Low-dose cytarabine versus intensive chemotherapy in the treatment of acute nonlymphocytic leukemia in the elderly.

    H Tilly;S Castaigne;D Bordessoule;P Casassus

  • Very long-term outcome of acute promyelocytic leukemia after treatment with all-trans retinoic acid and chemotherapy: the European APL Group experience

    Lionel Adès;Lionel Adès;Agnes Guerci;Emmanuel Raffoux;Miguel Sanz

  • All-transretinoic acid followed by intensive chemotherapy gives a high complete remission rate and may prolong remissions in newly diagnosed acute promyelocytic leukemia: a pilot study on 26 cases.

    P Fenaux;S Castaigne;H Dombret;E Archimbaud

  • Improved leukemia-free survival after postconsolidation immunotherapy with histamine dihydrochloride and interleukin-2 in acute myeloid leukemia: results of a randomized phase 3 trial.

    Mats Brune;Sylvie Castaigne;John Catalano;Kurt Gehlsen

  • Erosion of the chronic myeloid leukaemia stem cell pool by PPARγ agonists.

    Stéphane Prost;Francis Relouzat;Marc Spentchian;Yasmine Ouzegdouh

  • Gemtuzumab ozogamicin for de novo acute myeloid leukemia: final efficacy and safety updates from the open-label, phase III ALFA-0701 trial.

    Juliette Lambert;Cécile Pautas;Christine Terré;Emmanuel Raffoux

  • High efficacy and safety profile of fractionated doses of Mylotarg as induction therapy in patients with relapsed acute myeloblastic leukemia: a prospective study of the alfa group

    A.-L. Taksin;O. Legrand;E. Raffoux;T. De Revel

  • Prevalence, clinical profile, and prognosis of NPM mutations in AML with normal karyotype.

    Nicolas Boissel;Aline Renneville;Valeria Biggio;Nathalie Philippe

  • Randomized Study of Intensified Anthracycline Doses for Induction and Recombinant Interleukin-2 for Maintenance in Patients With Acute Myeloid Leukemia Age 50 to 70 Years: Results of the ALFA-9801 Study

    Cecile Pautas;Fatiha Merabet;Xavier Thomas;Emmanuel Raffoux

  • Resistance to all-trans retinoic acid (ATRA) therapy in relapsing acute promyelocytic leukemia: study of in vitro ATRA sensitivity and cellular retinoic acid binding protein levels in leukemic cells.

    L Delva;M Cornic;N Balitrand;F Guidez

Frequent Co-Authors

Hervé Dombret
Hervé Dombret Université Paris Cité
Claude Preudhomme
Claude Preudhomme University of Lille
Pierre Fenaux
Pierre Fenaux Université Paris Cité
Emmanuel Raffoux
Emmanuel Raffoux Hôpital Saint-Louis
Aline Renneville
Aline Renneville Institut Gustave Roussy
Sylvie Chevret
Sylvie Chevret Université Paris Cité
Christine Chomienne
Christine Chomienne Université Paris Cité
Nicolas Boissel
Nicolas Boissel Université Paris Cité
Stéphane de Botton
Stéphane de Botton Institut Gustave Roussy
Xavier Thomas
Xavier Thomas Lyon College

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