World's Best Scientists 2026 revealed!
Si-Xue Cheng

Si-Xue Cheng

D-Index & Metrics

Materials Science

D-Index
76
Citations
18292
World Ranking
3341
National Ranking
1071

Chemistry

D-Index
76
Citations
18272
World Ranking
4309
National Ranking
820

Overview

Si-Xue Cheng is affiliated with Wuhan University in China and has a research portfolio focused on Biochemistry, Genetics and Molecular Biology, as well as Engineering. Their work spans several interconnected subfields, including Molecular Biology, Biomedical Engineering, Immunology, Oncology, and Biomaterials.

Their research concentrates on topics such as Nanoplatforms for cancer theranostics, Immunotherapy and Immune Responses, RNA Interference and Gene Delivery, Advanced biosensing and bioanalysis techniques, Nanoparticle-Based Drug Delivery, CAR-T cell therapy research, and Combustion and Detonation Processes.

Si-Xue Cheng has published extensively in several venues, notably:

  • Advanced Functional Materials
  • Advanced Materials
  • Nano Letters
  • Analytical Chemistry
  • Nature Communications

Notable recent papers include:

  • "Inhibition of Tumor Progression through the Coupling of Bacterial Respiration with Tumor Metabolism" (2020, Angewandte Chemie International Edition)
  • "Tumor-Microenvironment-Triggered Ion Exchange of a Metal-Organic Framework Hybrid for Multimodal Imaging and Synergistic Therapy of Tumors" (2020, Advanced Materials)
  • "Aptamer/Peptide-Functionalized Genome-Editing System for Effective Immune Restoration through Reversal of PD-L1-Mediated Cancer Immunosuppression" (2020, Advanced Materials)
  • "Specific activation of cGAS-STING pathway by nanotherapeutics-mediated ferroptosis evoked endogenous signaling for boosting systemic tumor immunotherapy" (2023, Science Bulletin)
  • "Vascular disrupting agent induced aggregation of gold nanoparticles for photothermally enhanced tumor vascular disruption" (2020, Science Advances)

Frequently collaborating with Si-Xue Cheng are:

  • Xian-Zheng Zhang
  • Xiaohe Ren
  • Xiaoyan He
  • Di Han
  • Chang Xu

These collaborations have contributed to interdisciplinary research efforts integrating molecular biology, immunology, and biomedical engineering approaches to cancer research and nanotechnology applications.

Best Publications

  • Thermo-sensitive polymeric micelles based on poly(N-isopropylacrylamide) as drug carriers

    Hua Wei;Si-Xue Cheng;Xian-Zheng Zhang;Ren-Xi Zhuo

  • Drug self-delivery systems for cancer therapy

    Si-Yong Qin;Ai-Qing Zhang;Si-Xue Cheng;Lei Rong

  • Multifunctional envelope-type mesoporous silica nanoparticles for tumor-triggered targeting drug delivery.

    Jing Zhang;Zhe-Fan Yuan;Ya Wang;Wei-Hai Chen

  • Switching Apoptosis to Ferroptosis: Metal–Organic Network for High-Efficiency Anticancer Therapy

    Di-Wei Zheng;Di-Wei Zheng;Qi Lei;Jing-Yi Zhu;Jin-Xuan Fan

  • Phage-guided modulation of the gut microbiota of mouse models of colorectal cancer augments their responses to chemotherapy.

    Di-Wei Zheng;Xue Dong;Pei Pan;Ke-Wei Chen

  • Engineered Bacterial Bioreactor for Tumor Therapy via Fenton‐Like Reaction with Localized H 2 O 2 Generation

    Jin-Xuan Fan;Meng-Yun Peng;He Wang;Hao-Ran Zheng

  • Functionalized amphiphilic hyperbranched polymers for targeted drug delivery.

    Si Chen;Xian-Zheng Zhang;Si-Xue Cheng;Ren-Xi Zhuo

  • Overcoming the Heat Endurance of Tumor Cells by Interfering with the Anaerobic Glycolysis Metabolism for Improved Photothermal Therapy.

    Wei-Hai Chen;Guo-Feng Luo;Qi Lei;Sheng Hong

  • Self-assembled thermoresponsive micelles of poly(N-isopropylacrylamide-b-methyl methacrylate)

    Hua Wei;Xian-Zheng Zhang;Ying Zhou;Si-Xue Cheng

  • Optically-controlled bacterial metabolite for cancer therapy.

    Di Wei Zheng;Ying Chen;Zi Hao Li;Lu Xu

  • Self-assembled, thermosensitive micelles of a star block copolymer based on PMMA and PNIPAAm for controlled drug delivery.

    Hua Wei;Xianzheng Zhang;Cheng Cheng;Si-Xue Cheng

  • Multistep synthesis, growth mechanism, optical, and microwave absorption properties of ZnO dendritic nanostructures

    R. F. Zhuo;H. T. Feng;J. T. Chen;D. Yan

  • Calcium Carbonate/Carboxymethyl Chitosan Hybrid Microspheres and Nanospheres for Drug Delivery

    Jun Wang;Ji-Si Chen;Jing-Yi Zong;Dong Zhao

  • Composite microparticle drug delivery systems based on chitosan, alginate and pectin with improved pH-sensitive drug release property.

    Cui-Yun Yu;Bo-Cheng Yin;Wei Zhang;Si-Xue Cheng

  • Biotinylated thermoresponsive micelle self-assembled from double-hydrophilic block copolymer for drug delivery and tumor target.

    Cheng Cheng;Hua Wei;Bao-Xian Shi;Han Cheng

  • Strategies to improve the response rate of thermosensitive PNIPAAm hydrogels

    Xian-Zheng Zhang;Xiao-Ding Xu;Si-Xue Cheng;Ren-Xi Zhuo

  • Self-assembled thermo- and pH responsive micelles of poly(10-undecenoic acid-b-N-isopropylacrylamide) for drug delivery

    Hua Wei;Xian-Zheng Zhang;Han Cheng;Wen-Qin Chen

  • Galactosylated fluorescent labeled micelles as a liver targeting drug carrier

    De-Qun Wu;Bo Lu;Cong Chang;Chang-Sheng Chen

  • Comparison of diamino cross-linking in different polyimide solutions and membranes by precipitation observation and gas transport

    Lu Shao;Li Liu;Si-Xue Cheng;Yu-Dong Huang

  • Fabrication of supramolecular hydrogels for drug delivery and stem cell encapsulation.

    De-Qun Wu;Tao Wang;Bo Lu;Xiao-Ding Xu

Frequent Co-Authors

Xian-Zheng Zhang
Xian-Zheng Zhang Wuhan University
Ren-Xi Zhuo
Ren-Xi Zhuo Wuhan University
Tai-Shung Chung
Tai-Shung Chung National Taiwan University of Science and Technology
Bo Lu
Bo Lu The Ohio State University
Hua Li
Hua Li Nanyang Technological University
Jun Wang
Jun Wang South China University of Technology
Zhongwei Gu
Zhongwei Gu Sichuan University
Lu Shao
Lu Shao Harbin Institute of Technology
Suat Hong Goh
Suat Hong Goh National University of Singapore
David A. Schiraldi
David A. Schiraldi Case Western Reserve University

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