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Shoji Tajima

Shoji Tajima

D-Index & Metrics

Molecular Biology

D-Index
50
Citations
9815
World Ranking
2563
National Ranking
191

Overview

Shoji Tajima is affiliated with Osaka University in Japan and specializes in the field of Biochemistry, Genetics and Molecular Biology, with a focus on molecular biology. Their research encompasses multiple areas including epigenetics and DNA methylation, cancer-related gene regulation, RNA modifications and cancer, cancer genomics and diagnostics, pancreatic and hepatic oncology research, genetics and neurodevelopmental disorders, as well as genomics and chromatin dynamics.

The scientist has contributed to various publication venues, notably:

  • PLoS ONE
  • Advances in experimental medicine and biology
  • Neuropsychopharmacology
  • iScience
  • Genes to Cells

Selected recent papers authored or co-authored by Shoji Tajima include:

  • "A novel sensitive detection method for DNA methylation in circulating free DNA of pancreatic cancer," 2020, PLoS ONE
  • "Domain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases," 2022, Advances in experimental medicine and biology
  • "Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus," 2020, Neuropsychopharmacology
  • "DNMT1 regulates the timing of DNA methylation by DNMT3 in an enzymatic activity-dependent manner in mouse embryonic stem cells," 2022, PLoS ONE
  • "Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1," 2020, iScience

Frequent co-authors collaborating with Shoji Tajima are:

  • Isao Suetake
  • Takamasa Ito
  • Musashi Kubiura-Ichimaru
  • Masako Tada
  • Kohei Takeshita

The scientist's research topics primarily address epigenetics and DNA methylation with fourteen publications covering this theme. Other significant topics include cancer-related gene regulation with ten publications and RNA modifications in cancer, seen in four publications. Additional research interests extend into areas such as cancer genomics and diagnostics, pancreatic and hepatic oncology research, genetics and neurodevelopmental disorders, and genomics and chromatin dynamics.

Best Publications

  • The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

    Jafar Sharif;Masahiro Muto;Shin-ichiro Takebayashi;Isao Suetake

  • DNMT3L Stimulates the DNA Methylation Activity of Dnmt3a and Dnmt3b through a Direct Interaction

    Isao Suetake;Fuminori Shinozaki;Junichi Miyagawa;Hideyuki Takeshima

  • Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development

    Ryutaro Hirasawa;Hatsune Chiba;Hatsune Chiba;Masahiro Kaneda;Masahiro Kaneda;Shoji Tajima

  • Array-based genomic resequencing of human leukemia

    Y Yamashita;J Yuan;I Suetake;H Suzuki

  • Stage- and cell-specific expression of Dnmt3a and Dnmt3b during embryogenesis

    Daisuke Watanabe;Isao Suetake;Takashi Tada;Shoji Tajima

  • The signal recognition particle receptor is a complex that contains two distinct polypeptide chains.

    S Tajima;L Lauffer;V L Rath;P Walter

  • Processive Methylation of Hemimethylated CpG Sites by Mouse Dnmt1 DNA Methyltransferase

    Giedrius Vilkaitis;Isao Suetake;Saulius Klimašauskas;Shoji Tajima

  • Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1)

    Kohei Takeshita;Isao Suetake;Eiki Yamashita;Michihiro Suga;Michihiro Suga

  • Enzymatic properties of de novo-type mouse DNA (cytosine-5) methyltransferases

    Asako Aoki;Isao Suetake;Junichi Miyagawa;Takayuki Fujio

  • PCNA clamp facilitates action of DNA cytosine methyltransferase 1 on hemimethylated DNA

    Tetsuo Iida;Isao Suetake;Shoji Tajima;Hiroshi Morioka

  • 5-Hydroxymethylcytosine Marks Sites of DNA Damage and Promotes Genome Stability

    Georgia Rose Kafer;Xuan Li;Takuro Horii;Isao Suetake

  • The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells

    Yuuki Obata;Yukihiro Furusawa;Takaho A Endo;Jafar Sharif

  • MiR-29 represses the activities of DNA methyltransferases and DNA demethylases

    Sumiyo Morita;Takuro Horii;Mika Kimura;Takahiro Ochiya

  • Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance

    Satoshi Ishiyama;Atsuya Nishiyama;Yasushi Saeki;Kei Moritsugu

  • Evaluation of pH-responsive liposomes containing amino acid-based zwitterionic lipids for improving intracellular drug delivery in vitro and in vivo.

    Yosuke Obata;Shoji Tajima;Shinji Takeoka

  • Effect of lipid particle size on association of apolipoproteins with lipid.

    S Tajima;S Yokoyama;A Yamamoto

  • The DNA Methyltransferase Dnmt1 Directly Interacts with the SET and RING Finger-associated (SRA) Domain of the Multifunctional Protein Uhrf1 to Facilitate Accession of the Catalytic Center to Hemi-methylated DNA

    Ahmet Can Berkyurek;Isao Suetake;Kyohei Arita;Kohei Takeshita

  • Co-expression of de novo DNA methyltransferases Dnmt3a2 and Dnmt3L in gonocytes of mouse embryos

    Yasuhiro Sakai;Isao Suetake;Fuminori Shinozaki;Shohei Yamashina

  • Behavior of human apolipoprotein E in aqueous solutions and at interfaces.

    S Yokoyama;Y Kawai;S Tajima;A Yamamoto

  • Three novel DNMT3B mutations in Japanese patients with ICF syndrome

    Hisao Shirohzu;Takeo Kubota;Azumi Kumazawa;Azumi Kumazawa;Takashi Sado;Takashi Sado

Frequent Co-Authors

Shinji Yokoyama
Shinji Yokoyama Chubu University
Tohru Funahashi
Tohru Funahashi Osaka University
Ryo Sato
Ryo Sato Osaka University
Atsushi Nakagawa
Atsushi Nakagawa Osaka University
Yuji Matsuzawa
Yuji Matsuzawa Sumitomo Hospital
Masahiro Shirakawa
Masahiro Shirakawa Kyoto University
Haruhiko Koseki
Haruhiko Koseki RIKEN Center for Integrative Medical Sciences
Hiroyuki Sasaki
Hiroyuki Sasaki Kyushu University
Saburo Aimoto
Saburo Aimoto Osaka University
Takahiro Ochiya
Takahiro Ochiya Tokyo Medical University

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