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Neuroscience

D-Index
40
Citations
4861
World Ranking
8184
National Ranking
3506

Overview

Steve C. Danzer is affiliated with Cincinnati Children's Hospital Medical Center in the United States. Their research encompasses multiple aspects of neuroscience, biochemistry, genetics, molecular biology, and medicine, with a strong focus on molecular biology and cellular and molecular neuroscience.

Their scientific work includes investigations into neuroscience and neuropharmacology, ion channel regulation and function, epilepsy research and treatment, PI3K/AKT/mTOR signaling in cancer, retinal development and disorders, mitochondrial function and pathology, and pharmacological effects and toxicity studies.

Steve C. Danzer has authored numerous research papers published in journals such as Epilepsy Currents, Neurobiology of Disease, Experimental Neurology, eNeuro, and the British Journal of Anaesthesia. Notable recent publications include:

  • Effect of dexmedetomidine on sevoflurane-induced neurodegeneration in neonatal rats (2021), British Journal of Anaesthesia
  • PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes (2020), Neurobiology of Disease
  • The potassium channel Kv4.2 regulates dendritic spine morphology, electroencephalographic characteristics and seizure susceptibility in mice (2020), Experimental Neurology
  • mTOR-driven neural circuit changes initiate an epileptogenic cascade (2020), Progress in Neurobiology
  • The glucocorticoid receptor specific modulator CORT108297 reduces brain pathology following status epilepticus (2021), Experimental Neurology

Steve C. Danzer collaborates frequently with other researchers in their field. Prominent coauthors include Christina Groß, Candi L. LaSarge, Austin W. Drake, Durgesh Tiwari, and Kimberly L. Kraus. These collaborations reflect a consistent engagement with experts working on related neuroscience and epilepsy research topics.

Their work has appeared most frequently in Epilepsy Currents, with seven publications, as well as in Neurobiology of Disease, Experimental Neurology, and eNeuro, indicating a focus on epilepsy and neurological disorders in their research portfolio.

Best Publications

  • The effects of neonatal isoflurane exposure in mice on brain cell viability, adult behavior, learning, and memory.

    Andreas W. Loepke;George K. Istaphanous;John J. Mcauliffe;Lili Miles

  • Excessive Activation of mTOR in Postnatally Generated Granule Cells Is Sufficient to Cause Epilepsy

    Raymund Y.K. Pun;Isaiah J. Rolle;Candi L. LaSarge;Bethany E. Hosford

  • Comparison of the Neuroapoptotic Properties of Equipotent Anesthetic Concentrations of Desflurane, Isoflurane, or Sevoflurane in Neonatal Mice

    Unknown

  • Increased expression of brain-derived neurotrophic factor induces formation of basal dendrites and axonal branching in dentate granule cells in hippocampal explant cultures.

    Steve C. Danzer;Kristy R. C. Crooks;Donald C. Lo;James O. McNamara

  • Pilocarpine-Induced Seizures Cause Selective Time-Dependent Changes to Adult-Generated Hippocampal Dentate Granule Cells

    Unknown

  • Accumulation of Abnormal Adult-Generated Hippocampal Granule Cells Predicts Seizure Frequency and Severity

    Michael S. Hester;Steve C. Danzer;Steve C. Danzer

  • Depression, stress, epilepsy and adult neurogenesis

    Unknown

  • Cell age–specific vulnerability of neurons to anesthetic toxicity

    Unknown

  • Localization of Brain-Derived Neurotrophic Factor to Distinct Terminals of Mossy Fiber Axons Implies Regulation of Both Excitation and Feedforward Inhibition of CA3 Pyramidal Cells

    Steve C. Danzer;James O. McNamara

  • Heterogeneous Integration of Adult-Generated Granule Cells into the Epileptic Brain

    Unknown

  • MicroRNA-Mediated Downregulation of the Potassium Channel Kv4.2 Contributes to Seizure Onset

    Christina Gross;Christina Gross;Christina Gross;Xiaodi Yao;Tobias Engel;Durgesh Tiwari

  • Characterization and Quantification of Isoflurane-Induced Developmental Apoptotic Cell Death in Mouse Cerebral Cortex

    Unknown

  • Abnormalities of granule cell dendritic structure are a prominent feature of the intrahippocampal kainic acid model of epilepsy despite reduced postinjury neurogenesis.

    Brian L. Murphy;Rylon D. Hofacer;Rylon D. Hofacer;Christian N. Faulkner;Andreas W. Loepke;Andreas W. Loepke

  • Hippocampal granule cell pathology in epilepsy — A possible structural basis for comorbidities of epilepsy?

    Unknown

  • Structural plasticity of dentate granule cell mossy fibers during the development of limbic epilepsy.

    Steve C. Danzer;Xiaoping He;Andreas W. Loepke;Andreas W. Loepke;James O. McNamara

  • Impact of Traumatic Brain Injury on Neurogenesis

    Unknown

  • Altered morphology of hippocampal dentate granule cell presynaptic and postsynaptic terminals following conditional deletion of TrkB

    Steve C. Danzer;Robert J. Kotloski;Cynthia Walter;Maya Hughes

  • Ablation of Newly Generated Hippocampal Granule Cells Has Disease-Modifying Effects in Epilepsy

    Unknown

  • Impact of Corticosterone Treatment on Spontaneous Seizure Frequency and Epileptiform Activity in Mice with Chronic Epilepsy

    Olagide Wagner de Castro;Victor Rodrigues Santos;Raymund Y. K. Pun;Jessica M. McKlveen

  • Developmental and post‐injury cortical gliogenesis: A Genetic fate‐mapping study with Nestin‐CreER mice

    Unknown

  • Postnatal and Adult Neurogenesis in the Development of Human Disease

    Steve C. Danzer

  • Morphological changes among hippocampal dentate granule cells exposed to early kindling‐epileptogenesis

    Shatrunjai P. Singh;Shatrunjai P. Singh;Xiaoping He;James O. McNamara;Steve C. Danzer

  • Ontogeny of seizure-induced increases in BDNF immunoreactivity and TrkB receptor activation in rat hippocampus

    Steve C. Danzer;Xiaoping He;James O. McNamara

  • Hypothalamic-pituitary-adrenocortical axis dysfunction in epilepsy.

    Aynara C. Wulsin;Matia B. Solomon;Michael D. Privitera;Steve C. Danzer;Steve C. Danzer

  • PTEN deletion increases hippocampal granule cell excitability in male and female mice.

    Victor R. Santos;Raymund Y.K. Pun;Salwa R. Arafa;Candi L. LaSarge

  • Contributions of mature granule cells to structural plasticity in temporal lobe epilepsy.

    V. R. Santos;O. W. de Castro;O. W. de Castro;R. Y. K. Pun;M. S. Hester

  • PTEN deletion from adult-generated dentate granule cells disrupts granule cell mossy fiber axon structure

    Candi L. LaSarge;Victor R. Santos;Steve C. Danzer;Steve C. Danzer

  • Clonal Analysis of Newborn Hippocampal Dentate Granule Cell Proliferation and Development in Temporal Lobe Epilepsy

    Shatrunjai P. Singh;Shatrunjai P. Singh;Candi L. LaSarge;Amen An;Amen An;John J. McAuliffe

  • Functional disruption of stress modulatory circuits in a model of temporal lobe epilepsy

    Aynara C. Wulsin;Ana Franco-Villanueva;Christian Romancheck;Rachel L. Morano

  • Cannabinoid receptor 1/2 double-knockout mice develop epilepsy.

    Shane Rowley;Xiaofei Sun;Isabel V. Lima;Isabel V. Lima;Alexandra Tavenier

Frequent Co-Authors

Norberto Garcia-Cairasco
Norberto Garcia-Cairasco Universidade de São Paulo
Tobias Engel
Tobias Engel Royal College of Surgeons in Ireland
David C. Henshall
David C. Henshall Royal College of Surgeons in Ireland

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