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D-Index & Metrics

Medicine

D-Index
92
Citations
25316
World Ranking
11453
National Ranking
1087

Overview

Roy Bicknell is affiliated with the University of Birmingham in the United Kingdom. Their research primarily focuses on fields such as Biochemistry, Genetics and Molecular Biology, and Medicine.

The subfields of study explored by Bicknell include Molecular Biology, Immunology, Cancer Research, Immunology and Allergy, and Oncology. Their work often addresses topics related to glycosylation and glycoproteins research, cell adhesion molecules research, angiogenesis and VEGF in cancer, atherosclerosis and cardiovascular diseases, CAR-T cell therapy research, nanowire synthesis and applications, as well as immunotherapy and immune responses.

Among their recent publications are:

  • CAR T cells targeting tumor endothelial marker CLEC14A inhibit tumor growth, 2020, JCI Insight
  • Proteomics-based screening of the endothelial heparan sulfate interactome reveals that C-type lectin 14a (CLEC14A) is a heparin-binding protein, 2020, Journal of Biological Chemistry
  • Pulmonary MicroRNA Changes Alter Angiogenesis in Chronic Obstructive Pulmonary Disease and Lung Cancer, 2021, Biomedicines
  • An evaluation of the tumour endothelial marker CLEC14A as a therapeutic target in solid tumours, 2020, The Journal of Pathology Clinical Research
  • Type-H endothelial cell protein Clec14a orchestrates osteoblast activity during trabecular bone formation and patterning, 2024, Communications Biology

Frequent coauthors collaborating with Bicknell include Joseph Robinson, Katharine Whitworth, Elizabeth Jinks, Zsuzsanna Nagy, and Steven P. Lee.

Publication venues where Bicknell frequently publishes include:

  • JCI Insight
  • Journal of Biological Chemistry
  • Biomedicines
  • The Journal of Pathology Clinical Research
  • Communications Biology

Best Publications

  • Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis.

    M Ziche;L Morbidelli;R Choudhuri;H T Zhang

  • Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis.

    Micheie Relf;Susan LeJeune;Prudence A. E. Scott;Stephen Fox

  • Tumour vascular targeting

    Dario Neri;Roy Bicknell

  • Hypoxia and oxidative stress in breast cancer. Oxidative stress: its effects on the growth, metastatic potential and response to therapy of breast cancer.

    Nicholas S Brown;Roy Bicknell

  • Vascular Endothelial Growth Factor (VEGF) in Breast Cancer: Comparison of Plasma, Serum, and Tissue VEGF and Microvessel Density and Effects of Tamoxifen

    Jacqueline Adams;Pauline J. Carder;Sarah Downey;Mary A. Forbes

  • Thymidine phosphorylase is angiogenic and promotes tumor growth.

    Amir Moghaddam;Hua-Tang Zhang;Tai-Ping D. Fan;De-En Hu

  • Vascular Endothelial Growth Factor is a Predictor of Relapse and Stage Progression in Superficial Bladder Cancer

    J.P. Crew;T. O'Brien;M. Bradburn;S. Fuggle

  • Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis.

    Lukasz Huminiecki;Michael Gorn;Steven Suchting;Richard Poulsom

  • Delta4, an endothelial specific Notch ligand expressed at sites of physiological and tumor angiogenesis

    Carolina Mailhos;Ute Modlich;Julian Lewis;Adrian Harris

  • Different Angiogenic Pathways Characterize Superficial and Invasive Bladder Cancer

    Tim O'Brien;David Cranston;Susan Fuggle;Roy Bicknell

  • Enhancement of Tumor Growth and Vascular Density by Transfection of Vascular Endothelial Cell Growth Factor Into MCF–7 Human Breast Carcinoma Cells

    Hua-Tang Zhang;Paul Craft;Prudence A. E. Scott;Marina Ziche

  • An Angiogenic Role for the Neurokines Midkine and Pleiotrophin in Tumorigenesis

    Rangana Choudhuri;Hua Tang Zhang;Sandra Donnini;Marina Ziche

  • Controlling the vasculature : angiogenesis, anti-angiogenesis and vascular targeting of gene therapy

    Tai-Ping D. Fan;Rhys Jagger;Roy Bicknell

  • Anticancer strategies involving the vasculature

    Victoria L. Heath;Roy Bicknell

  • Differential Expression of Human Wnt Genes 2, 3, 4, and 7B in Human Breast Cell Lines and Normal and Disease States of Human Breast Tissue

    Emmanuel L. Huguet;Jill A. McMahon;Andrew P. McMahon;Roy Bicknell

  • Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer.

    Russell D. Leek;Kate L. Talks;Francesco Pezzella;Helen Turley

  • Angiogenesis in psoriasis.

    D Creamer;D Sullivan;R Bicknell;Jonathan Barker

  • THYMIDINE PHOSPHORYLASE, 2-DEOXY-D-RIBOSE AND ANGIOGENESIS

    Nicholas S. Brown;Roy Bicknell

  • The influence of oxygen tension and pH on the expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast tumor cells grown in vitro and in vivo.

    Leigh Griffiths;Gabi U. Dachs;Roy Bicknell;Adrian L. Harris

  • Heterogeneity of vascular endothelial cells with relevance to diagnosis of vascular tumours.

    I Kuzu;R Bicknell;A L Harris;M Jones

Frequent Co-Authors

adrian l harris
adrian l harris University of Oxford
Andreas Bikfalvi
Andreas Bikfalvi University of Bordeaux
Kevin C. Gatter
Kevin C. Gatter University of Oxford
Stephen B. Fox
Stephen B. Fox Peter MacCallum Cancer Centre
Marina Ziche
Marina Ziche University of Siena
Francesco Falciani
Francesco Falciani University of Liverpool
David H. Adams
David H. Adams Mount Sinai Hospital
Jonathan Barker
Jonathan Barker King's College London
Roslyn M. Bill
Roslyn M. Bill Aston University
Ian Zachary
Ian Zachary University College London

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