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Biology and Biochemistry

D-Index
54
Citations
41982
World Ranking
15322
National Ranking
6390

Overview

Robert Deans is affiliated with Osiris Therapeutics in the United States. Their research primarily encompasses fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on subfields such as Infectious Diseases, Immunology, Molecular Biology, Biomedical Engineering, and Genetics.

Their scientific contributions include work on the following main topics:

  • SARS-CoV-2 and COVID-19 Research
  • interferon and immune responses
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • SARS-CoV-2 detection and testing
  • Biosensors and Analytical Detection
  • CRISPR and Genetic Engineering

Deans has coauthored multiple papers with frequent collaborators including Mehdi Bouhaddou, Ann-Kathrin Reuschl, Benjamin J. Polacco, Lucy Thorne, and Manisha R. Ummadi.

Their recent publications demonstrate involvement in understanding viral-host interactions, immune regulation, and cell therapy, published in various scientific venues. Key recent papers include:

  • "SARS-CoV-2 variants evolve convergent strategies to remodel the host response," 2023, Cell
  • "Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories," 2022, bioRxiv (Cold Spring Harbor Laboratory)
  • "Augmented Expansion of Treg Cells From Healthy and Autoimmune Subjects via Adult Progenitor Cell Co-Culture," 2021, Frontiers in Immunology
  • "SARS-CoV-2 Variants Evolve Convergent Strategies to Remodel the Host Response," 2023, SSRN Electronic Journal
  • "Human Multipotent Adult Progenitor Cells Effectively Reduce Graft-vs-Host Disease While Preserving Graft-Vs-Leukemia Activity," 2021, Stem Cells

Frequent publication venues for Deans include UNC Libraries, Cell, bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, and SSRN Electronic Journal.

Best Publications

  • Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

    M. Dominici;K. Le Blanc;I. Mueller;I. Slaper-Cortenbach

  • Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo.

    Amelia Bartholomew;Cord Sturgeon;Mandy Siatskas;Karen Ferrer

  • Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement

    E.M. Horwitz;K. Le Blanc;M. Dominici;I. Mueller

  • Mesenchymal stem cells: Biology and potential clinical uses

    Robert J. Deans;Annemarie B. Moseley

  • Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep

    Kenneth W. Liechty;Tippi C. MacKenzie;Aimen F. Shaaban;Antoneta Radu

  • Defining protective responses to pathogens: cytokine profiles in leprosy lesions

    Masahiro Yamamura;Koichi Uyemura;Robert J. Deans;Kenneth Weinberg

  • T cell responses to allogeneic human mesenchymal stem cells: immunogenicity, tolerance, and suppression.

    Elena Klyushnenkova;Joseph D Mosca;Valentina Zernetkina;Manas K Majumdar

  • Elevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesis.

    M Linker-Israeli;R J Deans;D J Wallace;J Prehn

  • Mesenchymal stem cells are capable of homing to the bone marrow of non-human primates following systemic infusion

    Steven M. Devine;Amelia M. Bartholomew;Nadim Mahmud;Mary Nelson

  • International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials

    Jacques Galipeau;Mauro Krampera;John Barrett;Francesco Dazzi

  • Stem Cell Therapy as an Emerging Paradigm for Stroke (STEPS) II

    Sean I. Savitz;Michael Chopp;Robert Deans;S. T. Carmichael

  • Bioenergetic and functional consequences of bone marrow-derived multipotent progenitor cell transplantation in hearts with postinfarction left ventricular remodeling.

    Lepeng Zeng;Qingsong Hu;Xiaohong Wang;Abdul Mansoor

  • Specific interaction between coronavirus leader RNA and nucleocapsid protein.

    S A Stohlman;R S Baric;G N Nelson;L H Soe

  • Interactions between coronavirus nucleocapsid protein and viral RNAs: implications for viral transcription.

    R S Baric;G W Nelson;J O Fleming;R J Deans

  • Baboon Mesenchymal Stem Cells Can Be Genetically Modified to Secrete Human Erythropoietin In Vivo

    Amelia Bartholomew;Sheila Patil;Alastair Mackay;Mary Nelson

  • Multipotent Adult Progenitor Cells Prevent Macrophage-Mediated Axonal Dieback and Promote Regrowth after Spinal Cord Injury

    Sarah A. Busch;Jason A. Hamilton;Kevin P. Horn;Fernando X. Cuascut

  • EcoRI analysis of bacteriophage P22 DNA packaging

    Ethel Noland Jackson;David A. Jackson;Robert J. Deans

  • Biomanufacturing for clinically advanced cell therapies

    Ayesha Aijaz;Matthew Li;David Smith;Danika Khong

  • Intravenous multipotent adult progenitor cell therapy for traumatic brain injury: Preserving the blood brain barrier via an interaction with splenocytes

    Peter A. Walker;Shinil K. Shah;Shinil K. Shah;Fernando Jimenez;Michael H. Gerber

  • POSITION PAPER Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement

    EM Horwitz;K Le Blanc;M Dominici;I Mueller

Frequent Co-Authors

Richard T. Maziarz
Richard T. Maziarz Oregon Health & Science University
Massimo Dominici
Massimo Dominici University of Modena and Reggio Emilia
Edward K. Geissler
Edward K. Geissler University of Regensburg
Timothy I. M. Tree
Timothy I. M. Tree King's College London
Martin J. Hoogduijn
Martin J. Hoogduijn Erasmus University Rotterdam
Hans J. Schlitt
Hans J. Schlitt University of Regensburg
Cesar V. Borlongan
Cesar V. Borlongan University of South Florida
Diane S. Krause
Diane S. Krause Yale University
Carla C. Baan
Carla C. Baan Erasmus University Rotterdam
Daniel J. Weiss
Daniel J. Weiss University of Vermont

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