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Richard J. Caselli

Richard J. Caselli

D-Index & Metrics

Medicine

D-Index
94
Citations
35017
World Ranking
10429
National Ranking
5371

Overview

Richard J. Caselli is affiliated with the Mayo Clinic in the United States and has contributed extensively to research in medicine and neuroscience. Their work spans a range of subfields including physiology, psychiatry and mental health, neurology, cognitive neuroscience, and molecular biology.

Caselli's main research topics include:

  • Dementia and Cognitive Impairment Research
  • Alzheimer's disease research and treatments
  • Functional Brain Connectivity Studies
  • Neurological Disease Mechanisms and Treatments
  • EEG and Brain-Computer Interfaces
  • Advanced Neuroimaging Techniques and Applications
  • Neuroinflammation and Neurodegeneration Mechanisms

Frequent coauthors of Caselli are:

  • Eric M. Reiman
  • Kewei Chen
  • Bryan K. Woodruff
  • Yalin Wang
  • Yi Su

Caselli has published regularly in several venues, with notable frequent publication sites including:

  • Alzheimer s & Dementia
  • Journal of Alzheimer s Disease
  • Neurology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications

Among recent papers authored or coauthored by Caselli are:

  • APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline, 2020, Nature
  • Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study, 2020, Nature Communications
  • Effect of ApoE isoforms on mitochondria in Alzheimer disease, 2020, Neurology
  • DNA Methylation and Expression Profiles of Whole Blood in Parkinson's Disease, 2021, Frontiers in Genetics
  • SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19, 2022, Journal of Neuropathology & Experimental Neurology

Best Publications

  • Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E.

    Eric M. Reiman;Richard J. Caselli;Lang S. Yun;Kewei Chen

  • APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

    Axel Montagne;Daniel A. Nation;Abhay P. Sagare;Giuseppe Barisano

  • Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia

    Eric M. Reiman;Kewei Chen;Gene E. Alexander;Gene E. Alexander;Richard J. Caselli;Richard J. Caselli

  • Fibrillar amyloid-β burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

    Eric M. Reiman;Kewei Chen;Xiaofen Liu;Daniel Bandy

  • Multicenter Standardized 18F-FDG PET Diagnosis of Mild Cognitive Impairment, Alzheimer's Disease, and Other Dementias

    Lisa Mosconi;Wai H. Tsui;Wai H. Tsui;Karl Herholz;Alberto Pupi

  • TDP-43 A315T mutation in familial motor neuron disease.

    Michael A. Gitcho;Robert H. Baloh;Sumi Chakraverty;Kevin Mayo

  • Clinical, genetic, and neuropathologic characteristics of posterior cortical atrophy

    D. F. Tang-Wai;N. R. Graff-Radford;B. F. Boeve;D. W. Dickson

  • Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration

    Jennifer Gass;Ashley Cannon;Ian R. Mackenzie;Bradley Boeve

  • Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease.

    Eric M. Reiman;Richard J. Caselli;Kewei Chen;Gene E. Alexander

  • Steroid-Responsive Encephalopathy Associated With Autoimmune Thyroiditis

    Pablo Castillo;Bryan Woodruff;Richard Caselli;Steven Vernino

  • Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons.

    Winnie S. Liang;Eric M. Reiman;Jon Valla;Travis Dunckley

  • Vascular risk factors, incidence of MCI, and rates of progression to dementia.

    V Solfrizzi;F Panza;A M Colacicco;A D'Introno

  • TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics

    Ian R. Mackenzie;Alexandra M. Nicholson;Mohona Sarkar;James Messing

  • Longitudinal Modeling of Age-Related Memory Decline and the APOE ε4 Effect

    Richard J. Caselli;Amylou C. Dueck;David Osborne;Marwan N. Sabbagh

  • GAB2 Alleles Modify Alzheimer's Risk in APOE ε4 Carriers

    Eric M. Reiman;Jennifer A. Webster;Amanda J. Myers;Amanda J. Myers;John Hardy;John Hardy

  • Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis.

    Nicola J. Rutherford;Yong-Jie Zhang;Matt Baker;Jennifer M Gass

  • Common Kibra Alleles Are Associated with Human Memory Performance

    Andreas Papassotiropoulos;Andreas Papassotiropoulos;Dietrich A. Stephan;Matthew J. Huentelman;Frederic J. Hoerndli

  • Correlations between apolipoprotein E ε4 gene dose and brain-imaging measurements of regional hypometabolism

    Eric M. Reiman;Kewei Chen;Gene E. Alexander;Richard J. Caselli

  • Pathologic heterogeneity in clinically diagnosed corticobasal degeneration

    Bradley F. Boeve;D. M. Maraganore;J. E. Parisi;J. E. Ahlskog

  • Highly active antiretroviral therapy reverses brain metabolite abnormalities in mild HIV dementia.

    Chang L;Ernst T;Leonido-Yee M;Witt M

Frequent Co-Authors

Eric M. Reiman
Eric M. Reiman Arizona State University
Kewei Chen
Kewei Chen Arizona State University
Gene E. Alexander
Gene E. Alexander University of Arizona
Amylou C. Dueck
Amylou C. Dueck Mayo Clinic
Thomas G. Beach
Thomas G. Beach Banner Health
Rosa Rademakers
Rosa Rademakers University of Antwerp
Leslie C. Baxter
Leslie C. Baxter Mayo Clinic
Bradley F. Boeve
Bradley F. Boeve Mayo Clinic

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