D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics D-index 63 Citations 22,387 175 World Ranking 2049 National Ranking 77

Research.com Recognitions

Awards & Achievements

2020 - Fellow of the International Society for Computational Biology

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

Osamu Gotoh mostly deals with Genetics, Gene, Molecular biology, Complementary DNA and Nucleic acid sequence. In the subject of general Genetics, his work in Mitochondrial DNA, Genome and DNA replication is often linked to Limit, thereby combining diverse domains of study. Gene family, Pseudogene and Aryl hydrocarbon receptor nuclear translocator are the primary areas of interest in his Gene study.

His studies examine the connections between Pseudogene and genetics, as well as such issues in Gene cluster, with regards to Chimeric gene and Intron. His Molecular biology research is multidisciplinary, relying on both Cell culture, Sequence analysis, Repeated sequence and Nuclear pore. The various areas that he examines in his Nucleic acid sequence study include Amino acid and Peptide sequence.

His most cited work include:

  • P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature (2562 citations)
  • The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature (1464 citations)
  • An improved algorithm for matching biological sequences (1445 citations)

What are the main themes of his work throughout his whole career to date?

Osamu Gotoh focuses on Genetics, Gene, Molecular biology, Computational biology and Complementary DNA. His study in Genome, Mitochondrial DNA, Pseudogene, DNA and Phylogenetic tree are all subfields of Genetics. His Gene study frequently draws connections between adjacent fields such as Cytochrome P450.

Osamu Gotoh has included themes like Nucleic acid sequence, Biochemistry, TATA box, Transcription factor and Messenger RNA in his Molecular biology study. His studies in Computational biology integrate themes in fields like Genome project, Multiple sequence alignment, Sequence alignment, Genomics and Gene prediction. The various areas that Osamu Gotoh examines in his Intron study include Gene cluster and DNA sequencing.

He most often published in these fields:

  • Genetics (43.89%)
  • Gene (40.56%)
  • Molecular biology (23.89%)

What were the highlights of his more recent work (between 2010-2021)?

  • Genetics (43.89%)
  • Gene (40.56%)
  • Cancer research (4.44%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Genetics, Gene, Cancer research, Intron and Genome. His Computational biology research extends to the thematically linked field of Gene. His biological study spans a wide range of topics, including DNA microarray, Feature, Spliceosome and Phylogenetic tree.

In his study, A-DNA, Nucleotide Motif, Cluster analysis and Comparative genomics is strongly linked to Gray code, which falls under the umbrella field of Genome. He has researched Sequence alignment in several fields, including Gene family, Critical Assessment of Function Annotation, Pseudogene, Optimization problem and Computation. His Sequence analysis research includes themes of Complementary DNA and Molecular biology.

Between 2010 and 2021, his most popular works were:

  • Benchmarking spliced alignment programs including Spaln2, an extended version of Spaln that incorporates additional species-specific features (58 citations)
  • Evolution of cytochrome p450 genes from the viewpoint of genome informatics. (31 citations)
  • Evolution of cytochrome p450 genes from the viewpoint of genome informatics. (31 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

Osamu Gotoh mainly investigates Genetics, Gene, Genome, RNA splicing and Spliceosome. Critical Assessment of Function Annotation, Gene family, Sequence alignment, Genome project and A-DNA are the core of his Genetics study. His Computational biology research extends to Gene, which is thematically connected.

Osamu Gotoh interconnects Nuclear receptor, Transcription factor, Subfamily and Cytochrome P450 in the investigation of issues within Genome. His research in RNA splicing intersects with topics in DNA microarray, Feature, Phylogenetics and Phylogenetic tree. His study in Intron extends to Spliceosome with its themes.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature

David R. Nelson;Luc Koymans;Tetsuya Kamataki;John J. Stegeman.
Pharmacogenetics (1996)

3692 Citations

An improved algorithm for matching biological sequences

Osamu Gotoh.
Journal of Molecular Biology (1982)

2264 Citations

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature.

D R Nelson;T Kamataki;D J Waxman;F P Guengerich.
DNA and Cell Biology (1993)

2227 Citations

Substrate recognition sites in cytochrome P450 family 2 (CYP2) proteins inferred from comparative analyses of amino acid and coding nucleotide sequences.

O Gotoh.
Journal of Biological Chemistry (1992)

1405 Citations

Genome sequencing and analysis of Aspergillus oryzae

Masayuki Machida;Kiyoshi Asai;Motoaki Sano;Toshihiro Tanaka.
Nature (2005)

1359 Citations

Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: a pseudogene and a genuine gene

Yujiro Higashi;Hidefumi Yoshioka;Miyuki Yamane;Osamu Gotoh.
Proceedings of the National Academy of Sciences of the United States of America (1986)

674 Citations

cDNA cloning and structure of mouse putative Ah receptor

M. Ema;K. Sogawa;N. Watanabe;Y. Chujoh.
Biochemical and Biophysical Research Communications (1992)

518 Citations

Significant Improvement in Accuracy of Multiple Protein Sequence Alignments by Iterative Refinement as Assessed by Reference to Structural Alignments

Osamu Gotoh.
Journal of Molecular Biology (1996)

471 Citations

Ischemic brain edema following occlusion of the middle cerebral artery in the rat. I: The time courses of the brain water, sodium and potassium contents and blood-brain barrier permeability to 125I-albumin.

O Gotoh;T Asano;T Koide;K Takakura.
Stroke (1985)

433 Citations

Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos

Hideta Fujii;Takashi Sato;Sinya Kaneko;Osamu Gotoh.
The EMBO Journal (1997)

415 Citations

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