World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
60
Citations
17199
World Ranking
3780
National Ranking
336

Biology and Biochemistry

D-Index
60
Citations
17208
World Ranking
11760
National Ranking
906

Overview

Noel J. Buckley is affiliated with the University of Oxford in the United Kingdom. Their research spans multiple domains primarily within medicine, biochemistry, genetics, molecular biology, and neuroscience. Buckley's work focuses significantly on Alzheimer's disease and dementia-related topics, with a particular emphasis on identifying biomarkers and understanding neurodegeneration mechanisms.

The main fields of study that characterize Buckley's research output include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience

Within these fields, the notable subfields of study are:

  • Physiology
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Psychiatry and Mental health
  • Neurology

Buckley's research covers several key topics, such as:

  • Alzheimer's disease research and treatments
  • Dementia and Cognitive Impairment Research
  • Bioinformatics and Genomic Networks
  • Neuroscience and Neuropharmacology Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Metabolomics and Mass Spectrometry Studies
  • Neuroscience and Neural Engineering

They have published extensively in several journals and venues, indicating frequent contributions to:

  • Alzheimer's & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • IUPHAR/BPS Guide to Pharmacology CITE
  • Frontiers in Aging Neuroscience
  • Social Science & Medicine

Buckley's recent publications include:

  • Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life, 2023, Science Translational Medicine
  • High Blood Pressure and Risk of Dementia: A Two-Sample Mendelian Randomization Study in the UK Biobank, 2020, Biological Psychiatry
  • Δ9-tetrahydrocannabinol and 2-AG decreases neurite outgrowth and differentially affects ERK1/2 and Akt signaling in hiPSC-derived cortical neurons, 2020, Molecular and Cellular Neuroscience
  • Plasma Proteomic Biomarkers Relating to Alzheimer's Disease: A Meta-Analysis Based on Our Own Studies, 2021, Frontiers in Aging Neuroscience
  • Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort, 2020, Journal of Alzheimer's Disease

Buckley has collaborated frequently with a group of co-authors including:

  • Alejo Nevado-Holgado
  • Simon Lovestone
  • Liu Shi
  • Henrik Zetterberg
  • Sebastiaan Engelborghs

Best Publications

  • Muscarinic Receptor Subtypes

    E C Hulme;N J M Birdsall;N J Buckley

  • Identification of a family of muscarinic acetylcholine receptor genes

    T. I. Bonner;N. J. Buckley;A. C. Young;M. R. Brann

  • Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes.

    Tom I. Bonner;Alice C. Young;Mark R. Bran;Mark R. Bran;Noel J. Buckley

  • Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells.

    N J Buckley;T I Bonner;C M Buckley;M R Brann

  • Localization of a family of muscarinic receptor mRNAs in rat brain

    NJ Buckley;TI Bonner;Brann

  • Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes

    Alexander W. Bruce;Ian J. Donaldson;Ian C. Wood;Sally A. Yerbury

  • A microRNA-based gene dysregulation pathway in Huntington's disease.

    Rory Johnson;Chiara Zuccato;Nikolai D. Belyaev;Deborah J. Guest

  • A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets

    Diogo S. Castro;Ben Martynoga;Carlos Parras;Vidya Ramesh

  • Clusterin in Alzheimer's Disease: Mechanisms, Genetics, and Lessons From Other Pathologies.

    Evangeline M Foster;Adrià Dangla-Valls;Simon Lovestone;Elena M Ribe

  • A monoclonal antibody against meningococcus group B polysaccharides distinguishes embryonic from adult N-CAM.

    G Rougon;C Dubois;N Buckley;J L Magnani

  • Neuronal P2X7 Receptors Are Targeted to Presynaptic Terminals in the Central and Peripheral Nervous Systems

    Susan A. Deuchars;Lucy Atkinson;Ruth E. Brooke;Hanny Musa

  • Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells.

    S Lazareno;N J Buckley;F F Roberts

  • Widespread Disruption of Repressor Element-1 Silencing Transcription Factor/Neuron-Restrictive Silencer Factor Occupancy at Its Target Genes in Huntington's Disease

    Chiara Zuccato;Nikolai D Belyaev;Paola Conforti;Lezanne Ooi

  • Involvement of P2X7 receptors in the regulation of neurotransmitter release in the rat hippocampus

    Beáta Sperlágh;Attila Köfalvi;Jim Deuchars;Lucy Atkinson

  • Transcriptional repression by neuron-restrictive silencer factor is mediated via the Sin3-histone deacetylase complex.

    Avtar Roopra;Lisa Sharling;Ian C. Wood;Ian C. Wood;Teresa Briggs

  • REST regulates distinct transcriptional networks in embryonic and neural stem cells.

    Rory Johnson;Christina Hui-leng Teh;Galih Kunarso;Kee Yew Wong

  • Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis

    Alexandre A.S.F. Raposo;Francisca F. Vasconcelos;Daniela Drechsel;Corentine Marie

  • Distinct profiles of REST interactions with its target genes at different stages of neuronal development.

    Yuh-Man Sun;Deborah J. Greenway;Rory Johnson;Miyoko Street

  • Stimulation of arachidonic acid release and inhibition of mitogenesis by cloned genes for muscarinic receptor subtypes stably expressed in A9 L cells

    Bruce R. Conklin;Mark R. Brann;Noel J. Buckley;Alice L. Ma

  • Bradykinin excites rat sympathetic neurons by inhibition of M current through a mechanism involving B2 receptors and Gαq/11

    S Jones;D.A Brown;G Milligan;E Willer

Frequent Co-Authors

Lawrence W. Stanton
Lawrence W. Stanton Hamad bin Khalifa University
Pieter Jelle Visser
Pieter Jelle Visser Amsterdam University Medical Centers
Rory Johnson
Rory Johnson University College Dublin
Tom I. Bonner
Tom I. Bonner National Institutes of Health
Geoffrey Burnstock
Geoffrey Burnstock University College London
Lars Bertram
Lars Bertram University of Lübeck
Julius Popp
Julius Popp University Hospital of Lausanne
Simon Lovestone
Simon Lovestone University of Oxford
Jim Deuchars
Jim Deuchars University of Leeds
Kaj Blennow
Kaj Blennow University of Gothenburg

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