His main research concerns Cell biology, RE1-silencing transcription factor, Genetics, Neuroscience and MECP2. Gail Mandel interconnects Spider toxin, Sodium channel, Gene family, Voltage-dependent calcium channel and miR-132 in the investigation of issues within Cell biology. His research integrates issues of Epigenetics, Cellular differentiation and RCOR1 in his study of RE1-silencing transcription factor.
His RCOR1 study integrates concerns from other disciplines, such as Psychological repression, Corepressor, Chromatin, Molecular biology and Gene silencing. His Nervous system study in the realm of Neuroscience interacts with subjects such as Paranodal junction. His MECP2 study combines topics from a wide range of disciplines, such as Hippocampal formation and Rett syndrome.
His primary scientific interests are in Cell biology, Neuroscience, Sodium channel, Molecular biology and Genetics. His study in Cell biology is interdisciplinary in nature, drawing from both Protein subunit, Gene, Zebrafish, Neurotransmission and Acetylcholine receptor. His Neuroscience research incorporates elements of MECP2, Glycine receptor, Rett syndrome and Postsynaptic potential.
His research in Sodium channel intersects with topics in Internal medicine, Endocrinology, Skeletal muscle and Biochemistry. His Molecular biology research is multidisciplinary, incorporating perspectives in Complementary DNA and Reporter gene. His is doing research in Repressor, RE1-silencing transcription factor, Chromatin and Gene silencing, both of which are found in Genetics.
The scientist’s investigation covers issues in Neuroscience, Cell biology, MECP2, Rett syndrome and Genetics. His Neuroscience research is multidisciplinary, incorporating elements of Rest, Embryonic stem cell, RE1-silencing transcription factor and Cell type. His work deals with themes such as Histone, Gene expression and Neurotransmission, which intersect with Cell biology.
As a part of the same scientific study, he usually deals with the MECP2, concentrating on Heterochromatin and frequently concerns with RNA editing and Mutation. His Rett syndrome study which covers Disease that intersects with Microcephaly, Genetic enhancement and Period. His Genetics research includes elements of Endocrinology, Neuromuscular junction, Internal medicine and Voltage-dependent calcium channel.
Gail Mandel mainly focuses on Rett syndrome, MECP2, Genetics, Neuroscience and Cellular differentiation. The Rett syndrome study combines topics in areas such as Progenitor cell and Disease. His MECP2 research is multidisciplinary, relying on both AMPA receptor, Endocrinology and Cell type.
His Neuroscience research integrates issues from Neuropathology and Ca2+/calmodulin-dependent protein kinase. The various areas that Gail Mandel examines in his Cellular differentiation study include Chromatin, H3K4me3, Histone deacetylase, Repressor and Neurogenesis. His work carried out in the field of Chromatin brings together such families of science as RE1-silencing transcription factor, Histone deacetylase activity and Cell biology.
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Identification of a cyclic-AMP-responsive element within the rat somatostatin gene
Marc R. Montminy;Kevin A. Sevarino;John A. Wagner;Gail Mandel.
Proceedings of the National Academy of Sciences of the United States of America (1986)
Nomenclature of voltage-gated sodium channels.
Alan L. Goldin;Robert L. Barchi;John H. Caldwell;Franz Hofmann.
REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons
Jayhong A Chong;José Tapia-Ramirez;Sandra Kim;Juan J Toledo-Aral.
REST and Its Corepressors Mediate Plasticity of Neuronal Gene Chromatin throughout Neurogenesis
Nurit Ballas;Christopher Grunseich;Diane D. Lu;Joan C. Speh.
Defining the CREB Regulon: A Genome-Wide Analysis of Transcription Factor Regulatory Regions
Soren Impey;Sean R. McCorkle;Hyunjoo Cha-Molstad;Jami M. Dwyer.
Reciprocal actions of REST and a microRNA promote neuronal identity.
Cecilia Conaco;Stefanie Otto;Jong Jin Han;Gail Mandel.
Proceedings of the National Academy of Sciences of the United States of America (2006)
Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neurons
Juan J. Toledo-Aral;Brenda L. Moss;Brenda L. Moss;Zhi Jun He;Adam G. Koszowski.
Proceedings of the National Academy of Sciences of the United States of America (1997)
Primary structure and functional expression of a mammalian skeletal muscle sodium channel
James S. Trimmer;Sharon S. Cooperman;Sally A. Tomiko;Jiuying Zhou.
Combinatorial Roles of the Nuclear Receptor Corepressor in Transcription and Development
Kristen Jepsen;Ola Hermanson;Thandi M Onami;Anatoli S Gleiberman.
A Genetic Screen for Candidate Tumor Suppressors Identifies REST
Thomas F. Westbrook;Eric S. Martin;Michael R. Schlabach;Yumei Leng.
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