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D-Index
92
Citations
35610
World Ranking
11200
National Ranking
5757

Overview

Nigel S. Key is affiliated with the University of North Carolina at Chapel Hill in the United States and has contributed extensively to the field of Medicine, particularly focusing on hematology. Their research spans several subfields, including hematology, genetics, pulmonary and respiratory medicine, internal medicine, and molecular biology.

Key's work primarily engages with topics related to blood disorders and coagulation mechanisms. Main topics of their research include hemoglobinopathies and related disorders, hemophilia treatment and research, venous thromboembolism diagnosis and management, platelet disorders and treatments, blood coagulation and thrombosis mechanisms, iron metabolism and disorders, and blood properties and coagulation.

Their scholarly output includes publications in a variety of frequent venues such as UNC Libraries, Blood, Research and Practice in Thrombosis and Haemostasis, Blood Advances, and the Journal of Thrombosis and Haemostasis.

Notable recent papers featuring their contributions are:

  • Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: ASCO Guideline Update, 2023, Journal of Clinical Oncology
  • Gene Therapy with Etranacogene Dezaparvovec for Hemophilia B, 2023, New England Journal of Medicine
  • Two-Year Outcomes of Valoctocogene Roxaparvovec Therapy for Hemophilia A, 2023, New England Journal of Medicine
  • Coagulation Abnormalities and Thrombosis in Patients Infected With SARS-CoV-2 and Other Pandemic Viruses, 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways, 2020, Blood

Key frequently collaborates with researchers including Anton Ilich, Rafał Pawliński, Vimal K. Derebail, Steven W. Pipe, and Patrick Ellsworth. These co-authors have contributed to advancing understanding in overlapping areas of hemophilia, thrombosis, and blood coagulation disorders.

Best Publications

  • Guidelines for the management of hemophilia.

    A. Srivastava;A. K. Brewer;E. P. Mauser-Bunschoten;N. S. Key

  • C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor

    Jaroslav Cermak;Nigel S. Key;Ronald R. Bach;Jozsef Balla

  • Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: ASCO Clinical Practice Guideline Update

    Nigel S Key;Alok A Khorana;Nicole M Kuderer;Kari Bohlke

  • Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update 2014

    Gary H. Lyman;Gary H. Lyman;Kari Bohlke;Alok A. Khorana;Nicole M. Kuderer

  • Role of the Extrinsic Pathway of Blood Coagulation in Hemostasis and Thrombosis

    Nigel Mackman;Rachel E. Tilley;Nigel S. Key

  • D-dimer antigen: current concepts and future prospects.

    Soheir S. Adam;Nigel S. Key;Charles S. Greenberg

  • Definitions in hemophilia: communication from the SSC of the ISTH.

    V. S. Blanchette;N. S. Key;Rolf Ljung;M. J. Manco-Johnson

  • Sickle blood contains tissue factor–positive microparticles derived from endothelial cells and monocytes

    Arun S Shet;Omer Aras;Kalpna Gupta;Matthew J Hass

  • 2019 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer.

    Dominique Farge;Dominique Farge;Corinne Frere;Jean M Connors;Cihan Ay

  • Andrographolide attenuates inflammation by inhibition of NF-kappa B activation through covalent modification of reduced cysteine 62 of p50.

    Yi Feng Xia;Bu Qing Ye;Yi Dan Li;Jian Guo Wang

  • Measuring circulating cell-derived microparticles

    W. Jy;L. L. Horstman;J. J. Jimenez;Y. S. Ahn

  • Standardization of platelet-derived microparticle enumeration by flow cytometry with calibrated beads: results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop.

    R. Lacroix;S. Robert;P. Poncelet;R. S. Kasthuri

  • Blood coagulation: hemostasis and thrombin regulation.

    Kenichi A. Tanaka;Nigel S. Key;Jerrold H. Levy

  • Home Treatment of Mild to Moderate Bleeding Episodes Using Recombinant Factor VIIa (Novoseven) in Haemophiliacs with Inhibitors

    N S Key;L M Aledort;D Beardsley;H A Cooper

  • Iliofemoral Deep Venous Thrombosis: Safety and Efficacy Outcome during 5 Years of Catheter-directed Thrombolytic Therapy

    Haraldur Bjarnason;Janice R. Kruse;David A. Asinger;Gwen K. Nazarian

  • Induction of microparticle- and cell-associated intravascular tissue factor in human endotoxemia

    Omer Aras;Arun Shet;Ronald R. Bach;Jessica L. Hysjulien

  • Standardization of pre-analytical variables in plasma microparticle determination: results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop

    R. Lacroix;C. Judicone;M. Mooberry;M. Boucekine

  • Efficacy, safety, and pharmacokinetics of emicizumab prophylaxis given every 4 weeks in people with haemophilia A (HAVEN 4): a multicentre, open-label, non-randomised phase 3 study

    Steven W Pipe;Midori Shima;Michaela Lehle;Amy Shapiro

  • The North American Immune Tolerance Registry: practices, outcomes, outcome predictors.

    Donna M. DiMichele;B. L. Kroner;S. Adair;J. Addiego

  • Microparticle-associated tissue factor activity, venous thromboembolism and mortality in pancreatic, gastric, colorectal and brain cancer patients

    J. Thaler;C. Ay;Nigel Mackman;R. M. Bertina

Frequent Co-Authors

Nigel Mackman
Nigel Mackman University of North Carolina at Chapel Hill
Robert P. Hebbel
Robert P. Hebbel University of Minnesota
Dougald M. Monroe
Dougald M. Monroe University of North Carolina at Chapel Hill
Marilyn J. Manco-Johnson
Marilyn J. Manco-Johnson University of Colorado Anschutz Medical Campus
Gregory M. Vercellotti
Gregory M. Vercellotti University of Minnesota
Gary L. Nelsestuen
Gary L. Nelsestuen University of Minnesota
Jerrold H. Levy
Jerrold H. Levy Duke University
Mary Cushman
Mary Cushman University of Vermont
Alexander P. Reiner
Alexander P. Reiner University of Washington
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston

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