Naoya Asai

Overview

Best Publications

• Characterization of a multicomponent receptor for GDNF

  James J. S. Treanor;Laurie Goodman;Frederic de Sauvage;Donna M. Stone

  1344
  Citations

• Akt/PKB Regulates Actin Organization and Cell Motility via Girdin/APE

  Atsushi Enomoto;Hideki Murakami;Naoya Asai;Nobuhiro Morone

  530
  Citations

• A GPI-linked Protein That Interacts With Ret to Form a Candidate Neurturin Receptor

  Robert D. Klein;Robert D. Klein;Daniel Sherman;Wei-Hsien Ho;Donna Stone

  501
  Citations

• MECHANISM OF ACTIVATION OF THE RET PROTO-ONCOGENE BY MULTIPLE ENDOCRINE NEOPLASIA 2A MUTATIONS

  Naoya Asai;T. Iwashita;M. Matsuyama;M. Takahashi

  441
  Citations

• A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteins.

  Naoya Asai;Hideki Murakami;Toshihide Iwashita;Masahide Takahashi

  269
  Citations

• Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin

  Tomoya Kitamura;Naoya Asai;Atsushi Enomoto;Kengo Maeda

  266
  Citations

• Meflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis

  Yasuyuki Mizutani;Hiroki Kobayashi;Hiroki Kobayashi;Tadashi Iida;Naoya Asai

  252
  Citations

• Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis.

  Benson C Lu;Cristina Cebrian;Xuan Chi;Satu Kuure

  241
  Citations

• Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis.

  Xuan Chi;Odyssé Michos;Reena Shakya;Paul Riccio

  223
  Citations

• An Actin-Binding Protein Girdin Regulates the Motility of Breast Cancer Cells

  Ping Jiang;Atsushi Enomoto;Mayumi Jijiwa;Takuya Kato

  219
  Citations

• Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.

  Atsushi Enomoto;Naoya Asai;Takashi Namba;Yun Wang

  204
  Citations

• Biological properties of Ret with cysteine mutations correlate with multiple endocrine neoplasia type 2A, familial medullary thyroid carcinoma, and Hirschsprung's disease phenotype

  Shinji Ito;Toshihide Iwashita;Naoya Asai;Hideki Murakami

  199
  Citations

• Biological and biochemical properties of Ret with kinase domain mutations identified in multiple endocrine neoplasia type 2B and familial medullary thyroid carcinoma

  Toshihide Iwashita;Masashi Kato;Hideki Murakami;Naoya Asai

  169
  Citations

• Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse

  Keisuke Kuroda;Shinnosuke Yamada;Motoki Tanaka;Michiro Iizuka

  160
  Citations

• The RET proto-oncogene: a molecular therapeutic target in thyroid cancer.

  Yoshinori Kodama;Naoya Asai;Kumi Kawai;Mayumi Jijiwa

  160
  Citations

• Identification of tyrosine residues that are essential for transforming activity of the ret proto-oncogene with MEN2A or MEN2B mutation.

  Toshihide Iwashita;Naoya Asai;Hideki Murakami;Mutsushi Matsuyama

  159
  Citations

• Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities

  Masatoshi Ichihara;Yoshiki Murakumo;Akio Masuda;Toru Matsuura

  145
  Citations

• Homo-oligomer formation by basigin, an immunoglobulin superfamily member, via its N-terminal immunoglobulin domain.

  Seiya Yoshida;Maki Shibata;Satoshi Yamamoto;Masako Hagihara

  142
  Citations

• Enhanced phosphatidylinositol 3-kinase activity and high phosphorylation state of its downstream signalling molecules mediated by ret with the MEN 2B mutation.

  Hideki Murakami;Toshihide Iwashita;Naoya Asai;Yohei Shimono

  141
  Citations

• Mechanism of Ret Dysfunction by Hirschsprung Mutations Affecting Its Extracellular Domain

  Toshihide Iwashita;Hideki Murakami;Naoya Asai;Masahide Takahashi

  138
  Citations