D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 47 Citations 10,518 88 World Ranking 11734 National Ranking 3232
Biology and Biochemistry D-index 49 Citations 10,760 94 World Ranking 13529 National Ranking 5722

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Amino acid
  • Biochemistry

His primary areas of study are Biochemistry, Ion channel, Acetylcholine receptor, Biophysics and G alpha subunit. In the field of Biochemistry, his study on Small intestine, Membrane protein, Membrane and Membrane transport overlaps with subjects such as Affinity chromatography. In his study, Receptor is strongly linked to Neuroscience, which falls under the umbrella field of Ion channel.

In his research, Helical wheel, Amino acid, Neurotransmitter receptor and Stereochemistry is intimately related to Protein subunit, which falls under the overarching field of Acetylcholine receptor. His Biophysics research integrates issues from Protein structure, Binding site and GABAA receptor. His Protein structure research is multidisciplinary, incorporating perspectives in Xenopus and Gating.

His most cited work include:

  • Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption. (649 citations)
  • Acetylcholine receptor channel structure probed in cysteine-substitution mutants (579 citations)
  • TOWARD A STRUCTURAL BASIS FOR THE FUNCTION OF NICOTINIC ACETYLCHOLINE RECEPTORS AND THEIR COUSINS (537 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Biochemistry, Biophysics, Ion channel, Stereochemistry and GABAA receptor. His work on Equilibrative nucleoside transporter, Equilibrative nucleoside transporter 1 and Xenopus as part of general Biochemistry research is often related to Plasmodium falciparum and Hypoxanthine, thus linking different fields of science. His Biophysics research incorporates elements of Peptide sequence, Membrane, Cystic fibrosis transmembrane conductance regulator and Acetylcholine receptor.

The study incorporates disciplines such as Cytoplasm, Gating, Transmembrane protein, Protein structure and Cys-loop receptors in addition to Ion channel. His research in Stereochemistry focuses on subjects like Alpha, which are connected to G alpha subunit. His research integrates issues of gamma-Aminobutyric acid, Protein subunit, Allosteric regulation and Binding site in his study of GABAA receptor.

He most often published in these fields:

  • Biochemistry (40.59%)
  • Biophysics (32.67%)
  • Ion channel (28.71%)

What were the highlights of his more recent work (between 2011-2021)?

  • Plasmodium falciparum (13.86%)
  • Biochemistry (40.59%)
  • Medical education (6.93%)

In recent papers he was focusing on the following fields of study:

Myles H. Akabas mainly investigates Plasmodium falciparum, Biochemistry, Medical education, Equilibrative nucleoside transporter and Equilibrative nucleoside transporter 1. His study deals with a combination of Biochemistry and Purine metabolism. His Transporter course of study focuses on Binding site and Transmembrane domain and Transmembrane protein.

His Transmembrane domain research is multidisciplinary, incorporating elements of Protein subunit and Ion channel. As part of his studies on Ion channel, Myles H. Akabas frequently links adjacent subjects like Neuroscience. His studies deal with areas such as Glutamine and Acetylcholine receptor as well as Stereochemistry.

Between 2011 and 2021, his most popular works were:

  • Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. (257 citations)
  • Balance of Activity between LNvs and Glutamatergic Dorsal Clock Neurons Promotes Robust Circadian Rhythms in Drosophila (59 citations)
  • History and Outcomes of 50 Years of Physician-Scientist Training in Medical Scientist Training Programs. (50 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Amino acid
  • Biochemistry

Plasmodium falciparum, Biochemistry, Ion channel, Transmembrane protein and Nucleoside are his primary areas of study. His study on Plasmodium is often connected to Genetics, Vector, Small Molecule Libraries and Identification as part of broader study in Plasmodium falciparum. His Ion channel research includes themes of Protein structure, Protein subunit and Stereochemistry.

His study in Protein structure is interdisciplinary in nature, drawing from both Xenopus, Biophysics, Peptide sequence, Alanine and Patch clamp. His Protein subunit research includes elements of Gating, Lipid bilayer, Transmembrane domain and GABAA receptor. His work in Nucleoside addresses issues such as Adenosine, which are connected to fields such as Yeast and Equilibrative nucleoside transporter 1.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption.

Andong Qiu;Michaela Jansen;Antoinette Sakaris;Sang Hee Min.
Cell (2006)

934 Citations

TOWARD A STRUCTURAL BASIS FOR THE FUNCTION OF NICOTINIC ACETYLCHOLINE RECEPTORS AND THEIR COUSINS

Arthur Karlin;Myles H. Akabas.
Neuron (1995)

836 Citations

Acetylcholine receptor channel structure probed in cysteine-substitution mutants

Myles H. Akabas;David A. Stauffer;Ming Xu;Arthur Karlin.
Science (1992)

835 Citations

Substituted-cysteine accessibility method.

Arthur Karlin;Myles H. Akabas.
Methods in Enzymology (1998)

731 Citations

Emerging molecular mechanisms of general anesthetic action

Hugh C. Hemmings;Myles H. Akabas;Peter A. Goldstein;James R. Trudell.
Trends in Pharmacological Sciences (2005)

551 Citations

Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the α subunit

Myles H. Akabas;Christine Kaufmann;Patrick Archdeacon;Arthur Karlin.
Neuron (1994)

522 Citations

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong.
PLOS Pathogens (2016)

351 Citations

A bitter substance induces a rise in intracellular calcium in a subpopulation of rat taste cells.

Myles H. Akabas;Jane Dodd;Qais Al-Awqati.
Science (1988)

303 Citations

Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit.

Ming Xu;Myles H. Akabas.
The Journal of General Physiology (1996)

244 Citations

Identification of Acetylcholine Receptor Channel-Lining Residues in the M1 Segment of the .alpha.-Subunit

Myles H. Akabas;Arthur Karlin.
Biochemistry (1995)

243 Citations

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