His main research concerns Taste, Taste receptor, Biochemistry, Gustducin and TRPM5. The various areas that he examines in his Taste study include Transduction, Internal medicine and Endocrinology. The Taste receptor study combines topics in areas such as G protein and Cell biology.
His Lactisole, Taste bud, Sweetness and Sweet taste study, which is part of a larger body of work in Biochemistry, is frequently linked to Inositol trisphosphate, bridging the gap between disciplines. His study in Gustducin is interdisciplinary in nature, drawing from both Denatonium and GPR120. The concepts of his TAS1R3 study are interwoven with issues in TAS2R38 and Solitary chemosensory cells.
Robert F. Margolskee mainly investigates Taste, Biochemistry, Taste receptor, Gustducin and Cell biology. His Taste research is multidisciplinary, incorporating elements of Endocrinology and Internal medicine. Fusion protein is closely connected to Transgene in his research, which is encompassed under the umbrella topic of Taste receptor.
His studies in Gustducin integrate themes in fields like Heterotrimeric G protein and Transduction. His work deals with themes such as Neuroscience and Visual phototransduction, which intersect with Cell biology. His research in TAS1R3 intersects with topics in Taste bud, TAS2R38 and GPR120.
Robert F. Margolskee mainly focuses on Taste, Taste receptor, Cell biology, TAS1R3 and Biochemistry. His study of Gustducin is a part of Taste. His Taste receptor research integrates issues from Denatonium, Umami and Signal transduction.
In general Umami, his work in TAS1R1 is often linked to Ingestive behaviors linking many areas of study. His biological study spans a wide range of topics, including Taste bud and Bioinformatics. His work in the fields of TRPM5, Taste cell, Heterologous and Knockout mouse overlaps with other areas such as Functional activity.
Robert F. Margolskee mostly deals with Taste, Cell biology, Taste receptor, Biochemistry and Receptor. Robert F. Margolskee combines subjects such as Endocrinology and Internal medicine with his study of Taste. The study incorporates disciplines such as Adult stem cell, Tuft cell and TRPM5 in addition to Cell biology.
His Taste receptor research is multidisciplinary, relying on both Defensin, Umami, Disaccharidase and Respiratory epithelium. He usually deals with Receptor and limits it to topics linked to Secretion and Roux-en-Y anastomosis, Genetic model and Wild type. He interconnects SOX2 and Stem cell marker in the investigation of issues within Gustducin.
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Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1
Hyeung-Jin Jang;Zaza Kokrashvili;Michael J. Theodorakis;Olga D. Carlson.
Proceedings of the National Academy of Sciences of the United States of America (2007)
T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1
Robert F. Margolskee;Jane Dyer;Zaza Kokrashvili;Kieron S. H. Salmon.
Proceedings of the National Academy of Sciences of the United States of America (2007)
Transduction of bitter and sweet taste by gustducin
Gwendolyn T. Wong;Kimberley S. Gannon;Robert F. Margolskee.
Nature (1996)
Gustducin is a taste-cell-specific G protein closely related to the transducins
Susan K. McLaughlin;Peter J. McKinnon;Robert F. Margolskee.
Nature (1992)
Detection of Sweet and Umami Taste in the Absence of Taste Receptor T1r3
Sami Damak;Minqing Rong;Keiko Yasumatsu;Zaza Kokrashvili.
Science (2003)
Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac.
Marianna Max;Y. Gopi Shanker;Liquan Huang;Minqing Rong.
Nature Genetics (2001)
Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut
Michael R. Howitt;Sydney Lavoie;Monia Michaud;Arthur M. Blum.
Science (2016)
Trp8, a transient receptor potential channel expressed in taste receptor cells
Robert F Margolskee;Liquan Huang;Minqing Rong;Marianna Max.
Nature Neuroscience (2001)
Molecular mechanisms of bitter and sweet taste transduction.
Robert F. Margolskee.
Journal of Biological Chemistry (2002)
Heat activation of TRPM5 underlies thermal sensitivity of sweet taste
Karel Talavera;Keiko Yasumatsu;Thomas Voets;Guy Droogmans.
Nature (2005)
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