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D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
15987
World Ranking
10116
National Ranking
4426

Research.com Recognitions

  • 1999 - Member of the National Academy of Sciences
  • 1994 - Fellow of the American Academy of Arts and Sciences
  • 1989 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Arthur Karlin is affiliated with Columbia University in the United States. The scientist's research spans several fields, including Biochemistry, Genetics and Molecular Biology, Physics and Astronomy, and Medicine. Their work includes specific focus areas such as Molecular Biology, Radiation, Cardiology and Cardiovascular Medicine, Genetics, and Aerospace Engineering.

The main topics covered in Karlin's research include:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Nuclear Physics and Applications
  • Radiation Detection and Scintillator Technologies
  • Nicotinic Acetylcholine Receptors Study
  • Venomous Animal Envenomation and Studies
  • Cardiovascular Effects of Exercise

Karlin has contributed to multiple publications across various venues. Notable recent papers include:

  • Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins, 2020, Neuron
  • Rad regulation of CaV1.2 channels controls cardiac fight-or-flight response, 2022, Nature Cardiovascular Research
  • A membrane-associated phosphoswitch in Rad controls adrenergic regulation of cardiac calcium channels, 2024, Journal of Clinical Investigation
  • Measurement of the neutron cross section on argon between 95 and 720 MeV, 2023, Physical review. D/Physical review. D.
  • The Mini-CAPTAIN liquid argon time projection chamber, 2021, Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment

Frequent coauthors in Karlin's collaborations include:

  • Arianne Papa
  • Sergey I. Zakharov
  • Alexander N. Katchman
  • Bi-Xing Chen
  • Ao Liu

Karlin has also published books through the International Finance Corporation, Washington, DC eBooks, with titles such as:

  • Blended Concessional Finance and COVID-19, 2021
  • Blended Concessional Finance: The Benefits of Transparency and Access, 2021

Throughout their career, Karlin has been recognized by several scientific organizations, including election as a Member of the National Academy of Sciences in 1999, and as a Fellow of the American Academy of Arts and Sciences in 1994. Additionally, Karlin has been a Fellow of the American Association for the Advancement of Science since 1989.

Best Publications

  • Emerging structure of the nicotinic acetylcholine receptors.

    Arthur Karlin

  • TOWARD A STRUCTURAL BASIS FOR THE FUNCTION OF NICOTINIC ACETYLCHOLINE RECEPTORS AND THEIR COUSINS

    Arthur Karlin;Myles H. Akabas

  • Acetylcholine receptor channel structure probed in cysteine-substitution mutants

    Myles H. Akabas;David A. Stauffer;Ming Xu;Arthur Karlin

  • Substituted-cysteine accessibility method.

    Arthur Karlin;Myles H. Akabas

  • Identification of the alpha subunit half-cystine specifically labeled by an affinity reagent for the acetylcholine receptor binding site.

    P N Kao;A J Dwork;R R Kaldany;M L Silver

  • Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the α subunit

    Myles H. Akabas;Christine Kaufmann;Patrick Archdeacon;Arthur Karlin

  • Acetylcholine receptor binding site contains a disulfide cross-link between adjacent half-cystinyl residues.

    P N Kao;A Karlin

  • On the application of "a plausible model" of allosteric proteins to the receptor for acetylcholine.

    Arthur Karlin

  • Functional contributions of α5 subunit to neuronal acetylcholine receptor channels

    J. Ramirez-Latorre;C. R. Yu;X. Qu;F. Perin

  • Molecular weight in detergent solution of acetylcholine receptor from Torpedo californica.

    Jacqueline A. Reynolds;Arthur Karlin

  • Structure of nicotinic acetylcholine receptors.

    Arthur Karlin

  • Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates.

    David A. Stauffer;Arthur Karlin

  • Structure of the NMDA receptor channel M2 segment inferred from the accessibility of substituted cysteines

    Thomas Kuner;Lonnie P. Wollmuth;Arthur Karlin;Peter H. Seeburg

  • Chemical modification of the active site of the acetylcholine receptor.

    Arthur Karlin

  • Effects of blocking sulfhydryl groups and of reducing disulfide bonds on the acetylcholine-activated permeability system of the electroplax.

    Arthur Karlin;Eva Bartels

  • Affinity-labeling of purified acetylcholine receptor from Torpedo californica☆

    Cheryl L. Weill;Mark G. McNamee;Arthur Karlin

  • The location of the gate in the acetylcholine receptor channel.

    Gary G. Wilson;Arthur Karlin

  • Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment

    Hanne Hastrup;Arthur Karlin;Jonathan A. Javitch

  • Identification of Acetylcholine Receptor Channel-Lining Residues in the M1 Segment of the .alpha.-Subunit

    Myles H. Akabas;Arthur Karlin

  • CHAPTER 39 – Nicotinic Acetylcholine Receptors

    Arthur Karlin

Frequent Co-Authors

Guoxia Liu
Guoxia Liu University of Electronic Science and Technology of China
Myles H. Akabas
Myles H. Akabas Albert Einstein College of Medicine
David Cowburn
David Cowburn Albert Einstein College of Medicine
Jonathan A. Javitch
Jonathan A. Javitch Columbia University
Susan L. Hamilton
Susan L. Hamilton Baylor College of Medicine
Joseph S. Wall
Joseph S. Wall Brookhaven National Laboratory
Mitchell A. Winnik
Mitchell A. Winnik University of Toronto
Robert S. Kass
Robert S. Kass Columbia University
Lei Shi
Lei Shi National Institute on Drug Abuse
Samuel C. Silverstein
Samuel C. Silverstein Columbia University

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