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D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
20446
World Ranking
17400
National Ranking
747

Overview

Mario Pende is a researcher affiliated with Université Paris Cité in France. Their work spans key areas in biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology, cardiology and cardiovascular medicine, epidemiology, physiology, and surgery.

Their research topics include:

  • Autophagy in Disease and Therapy
  • Pancreatic function and diabetes
  • PI3K/AKT/mTOR signaling in cancer
  • Cardiovascular Effects of Exercise
  • Cardiomyopathy and Myosin Studies
  • Calcium signaling and nucleotide metabolism
  • Cancer, Hypoxia, and Metabolism

Frequent publication venues for Mario Pende include:

  • Cell
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Metabolism
  • Science Advances

Selected recent papers authored or co-authored by Mario Pende are:

  • "Nutrient-regulated control of lysosome function by signaling lipid conversion," 2023, Cell
  • "A homoeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism," 2024, Nature Metabolism
  • "mTOR and S6K1 drive polycystic kidney by the control of Afadin-dependent oriented cell division," 2020, Nature Communications
  • "PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruption," 2022, Science Advances
  • "Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling," 2021, Nature Communications

Mario Pende has collaborated frequently with several researchers, including:

  • Nicolas Kuperwasser
  • Anna Di Bona
  • Arianna Scalco
  • Riccardo Bariani
  • Rudy Celeghin

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway.

    Mario Pende;Mario Pende;Sung Hee Um;Virginie Mieulet;Melanie Sticker

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase.

    Hiroshi Shima;Mario Pende;Yi Chen;Stefano Fumagalli

  • The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

    David Shahbazian;Philippe P Roux;Virginie Mieulet;Michael S Cohen

  • Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice.

    Mario Pende;Sara C. Kozma;Muriel Jaquet;Viola Oorschot

  • Atrophy of S6K1 −/− skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control

    Mickaël Ohanna;Andrew K. Sobering;Thomas Lapointe;Lazaro Lorenzo

  • Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

    Valérie Risson;Laetitia Mazelin;Mila Roceri;Hervé Sanchez

  • Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathway

    M. Sandri;L. Barberi;A. Y. Bijlsma;A. Y. Bijlsma;B. Blaauw

  • Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program

    Chauvin C;Koka;Koka;Nouschi A;Nouschi A;Mieulet;Mieulet

  • mTORC1-mediated translational elongation limits intestinal tumour initiation and growth

    William J. Faller;Thomas J. Jackson;John R. P. Knight;Rachel A. Ridgway

  • Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors

    Frédéric Preitner;Mark Ibberson;Isobel Franklin;Christophe Binnert

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex

    Ning Liang;Ning Liang;Chi Zhang;Chi Zhang;Patricia Dill;Ganna Panasyuk;Ganna Panasyuk

  • S6 Kinase Deletion Suppresses Muscle Growth Adaptations to Nutrient Availability by Activating AMP Kinase

    Victor Aguilar;Victor Aguilar;Samira Alliouachene;Samira Alliouachene;Athanassia Sotiropoulos;Athanassia Sotiropoulos;Andrew Sobering;Andrew Sobering

  • AKT2 is essential to maintain podocyte viability and function during chronic kidney disease

    Guillaume Canaud;Frank Bienaimé;Frank Bienaimé;Amandine Viau;Caroline Treins

  • Rictor is a novel target of p70 S6 kinase-1

    C Treins;P H Warne;M A Magnuson;M Pende

  • Neurotransmitter- and Growth Factor-Induced cAMP Response Element Binding Protein Phosphorylation in Glial Cell Progenitors: Role of Calcium Ions, Protein Kinase C, and Mitogen-Activated Protein Kinase/Ribosomal S6 Kinase Pathway

    Mario Pende;Tracey L. Fisher;Peter B. Simpson;James T. Russell

  • Growth hormone promotes skeletal muscle cell fusion independent of insulin-like growth factor 1 up-regulation

    Athanassia Sotiropoulos;Mickaël Ohanna;Cécile Kedzia;Ram K. Menon

  • mTOR pathway activation drives lung cell senescence and emphysema

    Amal Houssaini;Amal Houssaini;Marielle Breau;Kanny Kebe;Shariq Abid

Frequent Co-Authors

Giambattista Bonanno
Giambattista Bonanno University of Genoa
Maurizio Raiteri
Maurizio Raiteri University of Genoa
Evelina Gatti
Evelina Gatti Aix-Marseille University
Jean-Ehrland Ricci
Jean-Ehrland Ricci Université Côte d'Azur
Marc Foretz
Marc Foretz Université Paris Cité
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Serge Adnot
Serge Adnot Paris-Est Créteil University
Sara C. Kozma
Sara C. Kozma University of Cincinnati
Yee-Joo Tan
Yee-Joo Tan National University of Singapore
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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