Mitsuhiro Yokoyama spends much of his time researching Internal medicine, Endocrinology, Nitric oxide synthase, Nitric oxide and Enos. His Internal medicine study combines topics from a wide range of disciplines, such as Eicosapentaenoic acid and Cardiology. His work in Endocrinology addresses issues such as Cell biology, which are connected to fields such as Oxidative stress, Gene expression, Angiogenesis and Pulmonary fibrosis.
The study incorporates disciplines such as Hypoxia, Calphostin C, Molecular biology, Cyclosporin a and Aldesleukin in addition to Nitric oxide synthase. Mitsuhiro Yokoyama combines subjects such as Lipopolysaccharide, Transgene, Arteriosclerosis and Citrulline with his study of Nitric oxide. His Enos research incorporates themes from Isoprenaline, Muscle hypertrophy, Protein kinase B and Hydralazine.
His scientific interests lie mostly in Internal medicine, Cardiology, Endocrinology, Heart failure and In patient. Many of his studies involve connections with topics such as Anesthesia and Internal medicine. His study in Hemodynamics, Dilated cardiomyopathy, Idiopathic dilated cardiomyopathy, Ventricular tachycardia and Stenosis falls under the purview of Cardiology.
Nitric oxide synthase, Endothelium, Nitric oxide, Vascular smooth muscle and Angiotensin II are among the areas of Endocrinology where he concentrates his study. His Nitric oxide synthase study focuses on Enos in particular.
Mitsuhiro Yokoyama mainly focuses on Internal medicine, Cardiology, Endocrinology, Heart failure and Coronary artery disease. As part of his studies on Internal medicine, Mitsuhiro Yokoyama often connects relevant areas like Eicosapentaenoic acid. Cardiology connects with themes related to Surgery in his study.
His study explores the link between Endocrinology and topics such as Endothelin 1 that cross with problems in Endothelial stem cell. The concepts of his Heart failure study are interwoven with issues in Hemodynamics and Atrial natriuretic peptide. His Coronary artery disease study combines topics in areas such as Statin, Primary prevention and Multiple risk factors.
His primary areas of investigation include Internal medicine, Cardiology, Endocrinology, Coronary artery disease and Myocardial infarction. As part of his studies on Internal medicine, he often connects relevant subjects like Eicosapentaenoic acid. His research investigates the connection with Cardiology and areas like Anesthesia which intersect with concerns in Apnea–hypopnea index.
His Coronary artery disease research includes elements of Proinflammatory cytokine, Primary prevention and Multiple risk factors. His research integrates issues of Stent, Circulatory system, Coronary flow reserve, Heart disease and Sudden cardiac death in his study of Myocardial infarction. His Sudden cardiac death research is multidisciplinary, relying on both Clinical endpoint and Unstable angina.
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Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis
Mitsuhiro Yokoyama;Hideki Origasa;Masunori Matsuzaki;Yuji Matsuzawa.
The Lancet (2007)
The Cardiac Mechanical Stretch Sensor Machinery Involves a Z Disc Complex that Is Defective in a Subset of Human Dilated Cardiomyopathy
Ralph Knöll;Masahiko Hoshijima;Hal M. Hoffman;Veronika Person.
Cell (2002)
Dysfunction of Endothelial Nitric Oxide Synthase and Atherosclerosis
Seinosuke Kawashima;Mitsuhiro Yokoyama.
Arteriosclerosis, Thrombosis, and Vascular Biology (2004)
Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice.
Masanori Ozaki;Seinosuke Kawashima;Tomoya Yamashita;Tetsuaki Hirase.
Journal of Clinical Investigation (2002)
Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors: Sub-analysis of primary prevention cases from the Japan EPA Lipid Intervention Study (JELIS)
Yasushi Saito;Mitsuhiro Yokoyama;Hideki Origasa;Masunori Matsuzaki.
Atherosclerosis (2008)
Regulation of Tight Junction Permeability and Occludin Phosphorylation by RhoA-p160ROCK-dependent and -independent Mechanisms
Tetsuaki Hirase;Seinosuke Kawashima;Elaine Y.M. Wong;Tomomi Ueyama.
Journal of Biological Chemistry (2001)
Expression of NADH/NADPH Oxidase p22phox in Human Coronary Arteries
Hiroshi Azumi;Nobutaka Inoue;Saori Takeshita;Yoshiyuki Rikitake.
Circulation (1999)
Hypotension and reduced nitric oxide-elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase.
Yoshitaka Ohashi;Seinosuke Kawashima;Ken-ichi Hirata;Tomoya Yamashita.
Journal of Clinical Investigation (1998)
Supersensitivity of Atherosclerotic Rabbit Aorta to Ergonovine: MEDIATION BY A SEROTONERGIC MECHANISM
Philip D. Henry;Mitsuhiro Yokoyama.
Journal of Clinical Investigation (1980)
Leptin stimulates rat aortic smooth muscle cell proliferation and migration
Akihiko Oda;Takahiro Taniguchi;Mitsuhiro Yokoyama.
The Kobe journal of the medical sciences (2001)
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