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Larry R. Pease

Larry R. Pease

D-Index & Metrics

Immunology

D-Index
57
Citations
18453
World Ranking
3582
National Ranking
1660

Overview

Larry R. Pease is affiliated with the Mayo Clinic in the United States. Their research spans multiple fields, with a central focus on immunology and microbiology. They have contributed to studies in biochemistry, genetics, molecular biology, and medicine.

The scientist has published extensively on topics related to immunotherapy and immune responses, immune cell function and interaction, cancer research and treatments, CAR-T cell therapy research, neuroinflammation and neurodegeneration mechanisms, T-cell and B-cell immunology, and cytomegalovirus and herpesvirus research.

Frequent coauthors in their work include:

  • Michael J. Hansen
  • Aaron J. Johnson
  • Wendy K. Nevala
  • Christopher A. Parks
  • Adam G. Schrum

Major publication venues where their work has appeared are:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Brain
  • Blood Advances

Some of the recent papers authored or co-authored by Larry R. Pease are:

  • Brain cancer induces systemic immunosuppression through release of non-steroid soluble mediators, 2020, Brain
  • Conditional Silencing of H-2Db Class I Molecule Expression Modulates the Protective and Pathogenic Kinetics of Virus-Antigen-Specific CD8 T Cell Responses during Theiler's Virus Infection, 2020, The Journal of Immunology
  • Public and private human T-cell clones respond differentially to HCMV antigen when boosted by CD3 copotentiation, 2020, Blood Advances
  • MHC class II-mediated spontaneous rejection of breast carcinomas expressing model neoantigens, 2025, Journal for ImmunoTherapy of Cancer
  • Public and private human T cell clones respond differentially to HCMV antigen when boosted by CD3 co-potentiation, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Their subfields of study particularly focus on immunology, molecular biology, oncology, epidemiology, and biotechnology.

Best Publications

  • Site-directed mutagenesis by overlap extension using the polymerase chain reaction.

    Steffan N. Ho;Henry D. Hunt;Robert M. Horton;Jeffrey K. Pullen

  • Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension.

    Robert M. Horton;Henry D. Hunt;Steffan N. Ho;Jeffrey K. Pullen

  • Gene Splicing by Overlap Extension: Tailor-Made Genes Using the Polymerase Chain Reaction

    Robert M Horton;Zeiling Cai;Steffan M Ho;Larry R Pease

  • Gene splicing and mutagenesis by PCR-driven overlap extension

    Karin L Heckman;Larry R Pease

  • Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen

    K. Christopher Garcia;Massimo Degano;Larry R. Pease;Mingdong Huang

  • Gene splicing by overlap extension.

    Robert M. Horton;Steffan N. Ho;Jeffrey K. Pullen;Henry D. Hunt

  • GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts

    Rosalie M. Sterner;Reona Sakemura;Michelle J. Cox;Nan Yang

  • Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors

    Ryan A. Wilcox;Dallas B. Flies;Gefeng Zhu;Aaron J. Johnson

  • Molecular cloning of the human eosinophil peroxidase. Evidence for the existence of a peroxidase multigene family.

    R M Ten;L R Pease;D J McKean;M P Bell

  • Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide binding.

    William C. Sha;Christopher A. Nelson;Rodney D. Newberry;Jeffrey K. Pullen

  • αβ T cell receptor interactions with syngeneic and allogeneic ligands: Affinity measurements and crystallization

    K. Christopher Garcia;Michelle D. Tallquist;Larry R. Pease;Anders Brunmark

  • Acidic precursor revealed in human eosinophil granule major basic protein cDNA

    Robert L. Barker;Gerald J. Gleich;Larry R. Pease

  • In Vitro Recombination and Mutagenesis by Overlap Extension PCR

    Robert J. Pogulis;Abbe N. Vallejo;Larry R. Pease

  • Eosinophil cationic protein cDNA. Comparison with other toxic cationic proteins and ribonucleases.

    R L Barker;D A Loegering;R M Ten;K J Hamann

  • Prevalent Class I-Restricted T-Cell Response to the Theiler’s Virus Epitope Db:VP2121–130 in the Absence of Endogenous CD4 Help, Tumor Necrosis Factor Alpha, Gamma Interferon, Perforin, or Costimulation through CD28

    Aaron J. Johnson;M. Kariuki Njenga;Michael J. Hansen;Scott T. Kuhns

  • Targeting of IgMκ Antibodies to Oligodendrocytes Promotes CNS Remyelination

    Kunihiko Asakura;David J. Miller;Larry R. Pease;Moses Rodriguez

  • Reprogrammed FoxP3+ T Regulatory Cells Become IL-17+ Antigen-Specific Autoimmune Effectors In Vitro and In Vivo

    Suresh Radhakrishnan;Rosalyn A. Cabrera;Erin L. Schenk;Pilar Nava-Parada

  • Cross-linking the B7 Family Molecule B7-DC Directly Activates Immune Functions of Dendritic Cells

    Loc T. Nguyen;Suresh Radhakrishnan;Bogoljub Ciric;Koji Tamada

  • Peptide Vaccine Given with a Toll-Like Receptor Agonist Is Effective for the Treatment and Prevention of Spontaneous Breast Tumors

    Pilar Nava-Parada;Guido Forni;Keith L. Knutson;Larry R. Pease

  • PERFORIN-DEPENDENT NEUROLOGIC INJURY IN A VIRAL MODEL OF MULTIPLE SCLEROSIS

    Paul D. Murray;Dorian B. McGavern;Xiaoqi Lin;M. Kariuki Njenga

  • Cigarette smoke-induced oxidative stress suppresses generation of dendritic cell IL-12 and IL-23 through ERK-dependent pathways.

    Paula R. Kroening;Terrance W. Barnes;Larry Pease;Andrew Limper

Frequent Co-Authors

Moses Rodriguez
Moses Rodriguez Mayo Clinic
Aaron J. Johnson
Aaron J. Johnson Mayo Clinic
Chella S. David
Chella S. David Mayo Clinic
Hirohito Kita
Hirohito Kita Mayo Clinic
Koji Tamada
Koji Tamada Yamaguchi University
Lieping Chen
Lieping Chen Yale University
David J. McKean
David J. McKean Mayo Clinic
Esteban Celis
Esteban Celis Augusta University

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