His main research concerns Immunology, Genetics, Overlap extension polymerase chain reaction, Major histocompatibility complex and Molecular biology. He has included themes like Myelin and Oligodendrocyte in his Immunology study. His works in Gene, Restriction enzyme and Chromosome localization are all subjects of inquiry into Genetics.
He has researched Overlap extension polymerase chain reaction in several fields, including Nucleic acid sequence, Polymerase, DNA polymerase, Primer and Mutagenesis. His work carried out in the field of Mutagenesis brings together such families of science as Site-directed mutagenesis and In vitro recombination. The Major histocompatibility complex study combines topics in areas such as CD8 and T-cell receptor.
Larry R. Pease mostly deals with Immunology, Immune system, T cell, Antigen and Genetics. His research integrates issues of Cytotoxic T cell, Remyelination and Virology in his study of Immunology. His Immune system study incorporates themes from Virus, Cancer and Function.
His work deals with themes such as Molecular biology, Cancer research and Cell biology, which intersect with T cell. His Genetics study is mostly concerned with Gene, Nucleic acid sequence, Overlap extension polymerase chain reaction, Mutagenesis and Allele. His Complementary DNA research extends to the thematically linked field of Nucleic acid sequence.
Larry R. Pease mainly focuses on T cell, Immune system, Antigen, Immunology and Cell biology. His T cell study integrates concerns from other disciplines, such as Molecular biology, Cancer research, Major histocompatibility complex and CD19. His Immune system research is multidisciplinary, relying on both Phenotype, Gene and Transcriptome.
His Gene study introduces a deeper knowledge of Genetics. His research investigates the link between Antigen and topics such as T-cell receptor that cross with problems in CD3 and Signal transduction. His Cell biology research includes elements of Acquired immune system, Cell culture, Amyotrophic lateral sclerosis, Epitope and Cytotoxic T cell.
His scientific interests lie mostly in Immunology, Cell biology, Antigen, Immune system and T cell. Immunology and Stroke are frequently intertwined in his study. His Antigen research is multidisciplinary, incorporating elements of Antigen Gene, Cytotoxic T cell, Viral vector and Influenza vaccine.
The various areas that Larry R. Pease examines in his Immune system study include Transcriptome, Melanoma and Gene. His work focuses on many connections between T cell and other disciplines, such as Acquired immune system, that overlap with his field of interest in Cell killing, Endoplasmic reticulum, Molecular biology and Cell division. He combines subjects such as Signal transduction, CTL* and Major histocompatibility complex with his study of T-cell receptor.
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Site-directed mutagenesis by overlap extension using the polymerase chain reaction.
Steffan N. Ho;Henry D. Hunt;Robert M. Horton;Jeffrey K. Pullen.
Gene (1989)
Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension.
Robert M. Horton;Henry D. Hunt;Steffan N. Ho;Jeffrey K. Pullen.
Gene (1989)
Gene Splicing by Overlap Extension: Tailor-Made Genes Using the Polymerase Chain Reaction
Robert M Horton;Zeiling Cai;Steffan M Ho;Larry R Pease.
BioTechniques (2013)
Gene splicing and mutagenesis by PCR-driven overlap extension
Karin L Heckman;Larry R Pease.
Nature Protocols (2007)
Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen
K. Christopher Garcia;Massimo Degano;Larry R. Pease;Mingdong Huang.
Science (1998)
Gene splicing by overlap extension.
Robert M. Horton;Steffan N. Ho;Jeffrey K. Pullen;Henry D. Hunt.
Methods in Enzymology (1993)
Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors
Ryan A. Wilcox;Dallas B. Flies;Gefeng Zhu;Aaron J. Johnson.
Journal of Clinical Investigation (2002)
Molecular cloning of the human eosinophil peroxidase. Evidence for the existence of a peroxidase multigene family.
R M Ten;L R Pease;D J McKean;M P Bell.
Journal of Experimental Medicine (1989)
Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide binding.
William C. Sha;Christopher A. Nelson;Rodney D. Newberry;Jeffrey K. Pullen.
Proceedings of the National Academy of Sciences of the United States of America (1990)
αβ T cell receptor interactions with syngeneic and allogeneic ligands: Affinity measurements and crystallization
K. Christopher Garcia;Michelle D. Tallquist;Larry R. Pease;Anders Brunmark.
Proceedings of the National Academy of Sciences of the United States of America (1997)
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