D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 50 Citations 24,000 144 World Ranking 3303 National Ranking 1322

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Immune system

His main research concerns Immunology, Genetics, Overlap extension polymerase chain reaction, Major histocompatibility complex and Molecular biology. He has included themes like Myelin and Oligodendrocyte in his Immunology study. His works in Gene, Restriction enzyme and Chromosome localization are all subjects of inquiry into Genetics.

He has researched Overlap extension polymerase chain reaction in several fields, including Nucleic acid sequence, Polymerase, DNA polymerase, Primer and Mutagenesis. His work carried out in the field of Mutagenesis brings together such families of science as Site-directed mutagenesis and In vitro recombination. The Major histocompatibility complex study combines topics in areas such as CD8 and T-cell receptor.

His most cited work include:

  • Site-directed mutagenesis by overlap extension using the polymerase chain reaction. (6904 citations)
  • Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension. (2979 citations)
  • Gene Splicing by Overlap Extension: Tailor-Made Genes Using the Polymerase Chain Reaction (1240 citations)

What are the main themes of his work throughout his whole career to date?

Larry R. Pease mostly deals with Immunology, Immune system, T cell, Antigen and Genetics. His research integrates issues of Cytotoxic T cell, Remyelination and Virology in his study of Immunology. His Immune system study incorporates themes from Virus, Cancer and Function.

His work deals with themes such as Molecular biology, Cancer research and Cell biology, which intersect with T cell. His Genetics study is mostly concerned with Gene, Nucleic acid sequence, Overlap extension polymerase chain reaction, Mutagenesis and Allele. His Complementary DNA research extends to the thematically linked field of Nucleic acid sequence.

He most often published in these fields:

  • Immunology (37.30%)
  • Immune system (24.86%)
  • T cell (21.62%)

What were the highlights of his more recent work (between 2012-2020)?

  • T cell (21.62%)
  • Immune system (24.86%)
  • Antigen (20.54%)

In recent papers he was focusing on the following fields of study:

Larry R. Pease mainly focuses on T cell, Immune system, Antigen, Immunology and Cell biology. His T cell study integrates concerns from other disciplines, such as Molecular biology, Cancer research, Major histocompatibility complex and CD19. His Immune system research is multidisciplinary, relying on both Phenotype, Gene and Transcriptome.

His Gene study introduces a deeper knowledge of Genetics. His research investigates the link between Antigen and topics such as T-cell receptor that cross with problems in CD3 and Signal transduction. His Cell biology research includes elements of Acquired immune system, Cell culture, Amyotrophic lateral sclerosis, Epitope and Cytotoxic T cell.

Between 2012 and 2020, his most popular works were:

  • Gene Splicing by Overlap Extension: Tailor-Made Genes Using the Polymerase Chain Reaction (1240 citations)
  • Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses. (31 citations)
  • A natural human IgM that binds to gangliosides is therapeutic in murine models of amyotrophic lateral sclerosis (21 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Immune system

His scientific interests lie mostly in Immunology, Cell biology, Antigen, Immune system and T cell. Immunology and Stroke are frequently intertwined in his study. His Antigen research is multidisciplinary, incorporating elements of Antigen Gene, Cytotoxic T cell, Viral vector and Influenza vaccine.

The various areas that Larry R. Pease examines in his Immune system study include Transcriptome, Melanoma and Gene. His work focuses on many connections between T cell and other disciplines, such as Acquired immune system, that overlap with his field of interest in Cell killing, Endoplasmic reticulum, Molecular biology and Cell division. He combines subjects such as Signal transduction, CTL* and Major histocompatibility complex with his study of T-cell receptor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Site-directed mutagenesis by overlap extension using the polymerase chain reaction.

Steffan N. Ho;Henry D. Hunt;Robert M. Horton;Jeffrey K. Pullen.
Gene (1989)

9197 Citations

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension.

Robert M. Horton;Henry D. Hunt;Steffan N. Ho;Jeffrey K. Pullen.
Gene (1989)

3790 Citations

Gene Splicing by Overlap Extension: Tailor-Made Genes Using the Polymerase Chain Reaction

Robert M Horton;Zeiling Cai;Steffan M Ho;Larry R Pease.
BioTechniques (2013)

2057 Citations

Gene splicing and mutagenesis by PCR-driven overlap extension

Karin L Heckman;Larry R Pease.
Nature Protocols (2007)

1473 Citations

Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen

K. Christopher Garcia;Massimo Degano;Larry R. Pease;Mingdong Huang.
Science (1998)

827 Citations

Gene splicing by overlap extension.

Robert M. Horton;Steffan N. Ho;Jeffrey K. Pullen;Henry D. Hunt.
Methods in Enzymology (1993)

594 Citations

Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors

Ryan A. Wilcox;Dallas B. Flies;Gefeng Zhu;Aaron J. Johnson.
Journal of Clinical Investigation (2002)

358 Citations

Molecular cloning of the human eosinophil peroxidase. Evidence for the existence of a peroxidase multigene family.

R M Ten;L R Pease;D J McKean;M P Bell.
Journal of Experimental Medicine (1989)

270 Citations

Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide binding.

William C. Sha;Christopher A. Nelson;Rodney D. Newberry;Jeffrey K. Pullen.
Proceedings of the National Academy of Sciences of the United States of America (1990)

220 Citations

αβ T cell receptor interactions with syngeneic and allogeneic ligands: Affinity measurements and crystallization

K. Christopher Garcia;Michelle D. Tallquist;Larry R. Pease;Anders Brunmark.
Proceedings of the National Academy of Sciences of the United States of America (1997)

208 Citations

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