His primary areas of investigation include Molecular biology, Cell biology, Biochemistry, Signal transduction and T cell. His work often combines Molecular biology and Cytosol studies. His Cell biology study combines topics from a wide range of disciplines, such as Cell culture and Antigen processing, Antigen presentation.
His work on Peptide sequence as part of his general Biochemistry study is frequently connected to Eosinophil-derived neurotoxin, Eosinophil cationic protein, Major basic protein and Eosinophil peroxidase, thereby bridging the divide between different branches of science. His work deals with themes such as Major histocompatibility complex and Antigen, which intersect with T cell. In general Antigen, his work in Hemagglutinin is often linked to Kappa linking many areas of study.
David J. McKean focuses on Molecular biology, Antigen, T cell, Immunology and Cell biology. The Molecular biology study combines topics in areas such as Cell culture, Alpha, Mutant, Beta and Epitope. His work carried out in the field of Antigen brings together such families of science as Immunoglobulin light chain, Antigen presentation and Antigen-presenting cell.
The study incorporates disciplines such as Calcitriol receptor and CD40 in addition to Antigen presentation. His research investigates the connection between T cell and topics such as T lymphocyte that intersect with problems in Lymphokine. His studies in Cell biology integrate themes in fields like Stimulation and Cellular differentiation.
David J. McKean spends much of his time researching Receptor, T cell, Immunology, Cell biology and T-cell receptor. His Receptor study combines topics in areas such as Molecular biology and Antigen presentation. His Molecular biology research incorporates themes from Beta, Cytokine, Signaling lymphocytic activation molecule and Nuclear factor kappa b.
His T cell study necessitates a more in-depth grasp of Immune system. David J. McKean works in the field of Cell biology, namely Signal transduction. His work on Immunological synapse as part of general T-cell receptor research is often related to Dynamin II, thus linking different fields of science.
David J. McKean mostly deals with Immune system, Internal medicine, Endocrinology, T cell and T-cell receptor. His study with Immune system involves better knowledge in Immunology. The various areas that he examines in his Internal medicine study include Dendritic cell and Antigen presentation.
His Antigen presentation study integrates concerns from other disciplines, such as Lipopolysaccharide, Calcitriol receptor, Receptor, Transforming growth factor beta and In vivo. His research in the fields of Immunological synapse overlaps with other disciplines such as Dynamin II. David J. McKean has researched T-cell receptor in several fields, including B cell, Antigen and Immunotherapy.
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Dendritic cell modulation by 1α,25 dihydroxyvitamin D3 and its analogs: A vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo
Matthew D. Griffin;Ward Lutz;Vy A. Phan;Lori A. Bachman.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin
David McKean;Konrad Huppi;Michael Bell;Louis Staudt.
Proceedings of the National Academy of Sciences of the United States of America (1984)
Polyquarternary amines prevent peptide loss from sequenators.
George E. Tarr;James F. Beecher;Michael Bell;David J. McKean.
Analytical Biochemistry (1978)
Biochemical and functional similarities between human eosinophil-derived neurotoxin and eosinophil cationic protein: Homology with ribonuclease
Gerald J. Gleich;David A. Loegering;Michael P. Bell;James L. Checkel.
Proceedings of the National Academy of Sciences of the United States of America (1986)
Potent inhibition of dendritic cell differentiation and maturation by vitamin D analogs.
Matthew D. Griffin;Ward H. Lutz;Vy A. Phan;Lori A. Bachman.
Biochemical and Biophysical Research Communications (2000)
Augmentation of T Cell Levels and Responses Induced by Androgen Deprivation
Anja C. Roden;Michael T. Moser;Samuel D. Tri;Maria Mercader.
Journal of Immunology (2004)
Ribonuclease activity associated with human eosinophil-derived neurotoxin and eosinophil cationic protein.
N R Slifman;D A Loegering;D J McKean;G J Gleich.
Journal of Immunology (1986)
Molecular cloning of the human eosinophil peroxidase. Evidence for the existence of a peroxidase multigene family.
R M Ten;L R Pease;D J McKean;M P Bell.
Journal of Experimental Medicine (1989)
Inhibition of Interleukin-1-stimulated NF-κB RelA/p65 Phosphorylation by Mesalamine Is Accompanied by Decreased Transcriptional Activity
L J Egan;D C Mays;C J Huntoon;M P Bell.
Journal of Biological Chemistry (1999)
Effects of p56lck deficiency on the growth and cytolytic effector function of an interleukin-2-dependent cytotoxic T-cell line.
Larry Karnitz;Shari L. Sutor;Toshihiko Torigoe;John C. Reed.
Molecular and Cellular Biology (1992)
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