What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Antibody
His primary areas of investigation include Molecular biology, Cell biology, Biochemistry, Signal transduction and T cell.
His work often combines Molecular biology and Cytosol studies.
His Cell biology study combines topics from a wide range of disciplines, such as Cell culture and Antigen processing, Antigen presentation.
His work on Peptide sequence as part of his general Biochemistry study is frequently connected to Eosinophil-derived neurotoxin, Eosinophil cationic protein, Major basic protein and Eosinophil peroxidase, thereby bridging the divide between different branches of science.
His work deals with themes such as Major histocompatibility complex and Antigen, which intersect with T cell.
In general Antigen, his work in Hemagglutinin is often linked to Kappa linking many areas of study.
His most cited work include:
- Dendritic cell modulation by 1α,25 dihydroxyvitamin D3 and its analogs: A vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo (521 citations)
- Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin (453 citations)
- Polyquarternary amines prevent peptide loss from sequenators. (397 citations)
What are the main themes of his work throughout his whole career to date?
David J. McKean focuses on Molecular biology, Antigen, T cell, Immunology and Cell biology.
The Molecular biology study combines topics in areas such as Cell culture, Alpha, Mutant, Beta and Epitope.
His work carried out in the field of Antigen brings together such families of science as Immunoglobulin light chain, Antigen presentation and Antigen-presenting cell.
The study incorporates disciplines such as Calcitriol receptor and CD40 in addition to Antigen presentation.
His research investigates the connection between T cell and topics such as T lymphocyte that intersect with problems in Lymphokine.
His studies in Cell biology integrate themes in fields like Stimulation and Cellular differentiation.
He most often published in these fields:
- Molecular biology (58.18%)
- Antigen (30.91%)
- T cell (25.45%)
What were the highlights of his more recent work (between 2000-2008)?
- Receptor (14.55%)
- T cell (25.45%)
- Immunology (23.64%)
In recent papers he was focusing on the following fields of study:
David J. McKean spends much of his time researching Receptor, T cell, Immunology, Cell biology and T-cell receptor.
His Receptor study combines topics in areas such as Molecular biology and Antigen presentation.
His Molecular biology research incorporates themes from Beta, Cytokine, Signaling lymphocytic activation molecule and Nuclear factor kappa b.
His T cell study necessitates a more in-depth grasp of Immune system.
David J. McKean works in the field of Cell biology, namely Signal transduction.
His work on Immunological synapse as part of general T-cell receptor research is often related to Dynamin II, thus linking different fields of science.
Between 2000 and 2008, his most popular works were:
- Dendritic cell modulation by 1α,25 dihydroxyvitamin D3 and its analogs: A vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo (521 citations)
- Augmentation of T Cell Levels and Responses Induced by Androgen Deprivation (196 citations)
- Dynamin 2 regulates T cell activation by controlling actin polymerization at the immunological synapse (140 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Antibody
David J. McKean mostly deals with Immune system, Internal medicine, Endocrinology, T cell and T-cell receptor.
His study with Immune system involves better knowledge in Immunology.
The various areas that he examines in his Internal medicine study include Dendritic cell and Antigen presentation.
His Antigen presentation study integrates concerns from other disciplines, such as Lipopolysaccharide, Calcitriol receptor, Receptor, Transforming growth factor beta and In vivo.
His research in the fields of Immunological synapse overlaps with other disciplines such as Dynamin II.
David J. McKean has researched T-cell receptor in several fields, including B cell, Antigen and Immunotherapy.
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