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Biology and Biochemistry

D-Index
47
Citations
7675
World Ranking
18730
National Ranking
427

Overview

Juan M. Hurle is affiliated with the University of Cantabria in Spain. Their research primarily focuses on areas within biochemistry, genetics, and molecular biology, with additional contributions to medicine. The scientific work spans several subfields including molecular biology, genetics, epidemiology, developmental biology, and physiology.

The research topics covered by Hurle include congenital limb and hand anomalies, bone fractures and treatments, telomeres, telomerase, and senescence, mesenchymal stem cell research, pluripotent stem cells research, epigenetics and DNA methylation, and cancer-related gene regulation.

Juan M. Hurle has contributed to several peer-reviewed papers, reflecting a focus on vertebrate limb development and cellular processes involved in embryonic tissue remodeling. Notable recent publications include:

  • The methylation status of the embryonic limb skeletal progenitors determines their cell fate in chicken, 2020, Communications Biology
  • Cell death in the developing vertebrate limb: A locally regulated mechanism contributing to musculoskeletal tissue morphogenesis and differentiation, 2020, Developmental Dynamics
  • Confluence of Cellular Degradation Pathways During Interdigital Tissue Remodeling in Embryonic Tetrapods, 2020, Frontiers in Cell and Developmental Biology
  • Transforming growth factor beta signaling: The master sculptor of fingers, 2021, Developmental Dynamics
  • Histone Epigenetic Signatures in Embryonic Limb Interdigital Cells Fated to Die, 2021, Cells

The frequent co-authors collaborating with Juan M. Hurle include Carlos I. Lorda-Diez, Juan A. Montero, Cristina Duarte-Olivenza, Cristina Sánchez-Fernández, and Goretti Moran. This network of collaborators has supported research in developmental biology and related fields.

Hurle's work is regularly published in journals such as Developmental Dynamics, Frontiers in Cell and Developmental Biology, Cells, Communications Biology, and Cell Death and Disease. These venues reflect the scientist's focus on cellular biology and developmental mechanisms.

Best Publications

  • Role of BMP-2 and OP-1 (BMP-7) in programmed cell death and skeletogenesis during chick limb development

    D. Macias;Y. Ganan;T.K. Sampath;M.E. Piedra

  • Role of TGF beta s and BMPs as signals controlling the position of the digits and the areas of interdigital cell death in the developing chick limb autopod

    Y. Ganan;D. Macias;M. Duterque-Coquillaud;M.A. Ros

  • The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb

    R. Merino;J. Rodriguez-Leon;D. Macias;Y. Ganan

  • Morphogenesis of Digits in the Avian Limb Is Controlled by FGFs, TGFβs, and Noggin through BMP Signaling

    Ramón Merino;Yolanda Gañan;Domingo Macias;Aris N. Economides

  • Expression and function of Gdf-5 during digit skeletogenesis in the embryonic chick leg bud.

    R. Merino;D. Macias;Y. Gañan;A.N. Economides

  • Analysis of the molecular cascade responsible for mesodermal limb chondrogenesis : Sox genes and BMP signaling

    J Chimal-Monroy;J Rodriguez-Leon;J.A Montero;Y Gañan

  • Transforming Growth Factors β Coordinate Cartilage and Tendon Differentiation in the Developing Limb Mesenchyme

    Carlos I. Lorda-Diez;Juan A. Montero;Carmen Martinez-Cue;Juan A. Garcia-Porrero

  • Programmed cell death in the developing limb.

    Vanessa Zuzarte-Luis;Juan M Hurle

  • Internucleosomal DNA fragmentation and programmed cell death (apoptosis) in the interdigital tissue of the embryonic chick leg bud.

    V. Garcia-Martinez;D. Macias;Y. Ganan;J.M. Garcia-Lobo

  • A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways

    V Zuzarte-Luı́s;J.A Montero;J Rodriguez-León;R Merino

  • Morphological diversity of the avian foot is related with the pattern of msx gene expression in the developing autopod.

    Yolanda Gañan;Domingo Macias;Ricardo D. Basco;Ramón Merino

  • Retinoic acid regulates programmed cell death through BMP signalling.

    J Rodriguez-Leon;R Merino;D Macias;Y Gañan

  • Role of FGFs in the control of programmed cell death during limb development.

    Juan Antonio Montero;Yolanda Gañan;Domingo Macias;Joaquin Rodriguez-Leon

  • Programmed cell death in the embryonic vertebrate limb.

    Vanessa Zuzarte-Luis;Juan M. Hurle

  • Morphological changes in the normal pattern of ventricular myoarchitecture in the developing human heart

    Damian Sanchez‐Quintana;Virginio Garcia‐Martinez;Vicente Climent;Juan M. Hurle

  • Activin/TGFbeta and BMP crosstalk determines digit chondrogenesis.

    Juan A. Montero;Carlos I. Lorda-Diez;Yolanda Gañan;Domingo Macias

  • Bone morphogenetic proteins regulate interdigital cell death in the avian embryo.

    Ramón Merino;Yolanda Gañán;Domingo Macias;Joaquín Rodríguez-León

  • Immunohistological and ultrastructural study of the developing tendons of the avian foot.

    M. A. Ros;F. B. Rivero;J. R. Hinchliffe;J. M. Hurle

  • Control of digit formation by activin signalling.

    R. Merino;D. Macias;Y. Ganan;J. Rodriguez-Leon

  • Developmental patterning of the vertebrate limb

    J. R. Hinchliffe;Juan M. Hurle;Dennis Summerbell

Frequent Co-Authors

Ramón Merino
Ramón Merino Spanish National Research Council
Isabel Varela-Nieto
Isabel Varela-Nieto Spanish National Research Council
Aris N. Economides
Aris N. Economides Regeneron (United States)
John F. Fallon
John F. Fallon University of Wisconsin–Madison
Fred Sinowatz
Fred Sinowatz Ludwig-Maximilians-Universität München
Lynn Y. Sakai
Lynn Y. Sakai Oregon Health & Science University
Michael Solursh
Michael Solursh University of Iowa
Eng-Ang Ling
Eng-Ang Ling National University of Singapore
Niels Keiding
Niels Keiding University of Copenhagen
M. Angela Nieto
M. Angela Nieto Spanish National Research Council

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