World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
28350
World Ranking
5812
National Ranking
2749

Overview

Jianjun Chen is affiliated with the University of Cincinnati in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant focus on Molecular Biology, Cancer Research, Immunology, Oncology, and Hematology as key subfields.

The scientist's main research topics include RNA modifications and cancer, cancer-related molecular mechanisms research, cancer-related gene regulation, RNA research and splicing, epigenetics and DNA methylation, RNA and protein synthesis mechanisms, and acute myeloid leukemia research.

Jianjun Chen has authored several recent papers illustrating their research interests. Selected publications include:

  • m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer, 2020, Cancer Cell
  • Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion, 2020, Cancer Cell
  • RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia, 2020, Cell Stem Cell
  • R-2-hydroxyglutarate Attenuates Aerobic Glycolysis in Leukemia by Targeting the FTO/m6A/PFKP/LDHB Axis, 2021, Molecular Cell
  • METTL16 Exerts an m6A-Independent Function to Facilitate Translation and Tumorigenesis, 2022, Nature Cell Biology

Jianjun Chen collaborates frequently with fellow researchers in their domain. Key co-authors have included:

  • Rui Su
  • Xiaolan Deng
  • Zhenhua Chen
  • Ying Qing
  • Chao Shen

The scientist has published extensively in venues such as Blood, Cancer Research, Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), and PubMed.

  • Blood
  • Cancer Research
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PubMed

Jianjun Chen also contributed to book publications, including a work titled Epigenetics in Oncology published by Springer Science+Business Media in 2023.

Best Publications

  • Recognition of RNA N 6 -methyladenosine by IGF2BP proteins enhances mRNA stability and translation

    Huilin Huang;Huilin Huang;Hengyou Weng;Hengyou Weng;Wenju Sun;Xi Qin;Xi Qin

  • FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6-Methyladenosine RNA Demethylase

    Zejuan Li;Hengyou Weng;Hengyou Weng;Rui Su;Xiaocheng Weng;Xiaocheng Weng

  • R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling

    Rui Su;Lei Dong;Chenying Li;Sigrid Nachtergaele

  • METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification

    Hengyou Weng;Huilin Huang;Huizhe Wu;Xi Qin

  • Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.

    Yue Huang;Rui Su;Yue Sheng;Lei Dong;Lei Dong

  • MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia

    Shuangli Mi;Jun Lu;Jun Lu;Miao Sun;Zejuan Li

  • miR-21 plays a pivotal role in gastric cancer pathogenesis and progression

    Zhiyu Zhang;Zejuan Li;Caiping Gao;Ping Chen

  • RNA N6-methyladenosine modification in cancers: current status and perspectives

    Xiaolan Deng;Xiaolan Deng;Xiaolan Deng;Rui Su;Rui Su;Hengyou Weng;Hengyou Weng;Huilin Huang;Huilin Huang

  • Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm

    Jiangbo Wei;Jiangbo Wei;Fange Liu;Fange Liu;Zhike Lu;Zhike Lu;Zhike Lu;Qili Fei;Qili Fei

  • Distinct microRNA expression profiles in acute myeloid leukemia with common translocations

    Zejuan Li;Jun Lu;Jun Lu;Miao Sun;Shuangli Mi

  • Histone H3 trimethylation at lysine 36 guides m 6 A RNA modification co-transcriptionally

    Huilin Huang;Huilin Huang;Hengyou Weng;Hengyou Weng;Keren Zhou;Tong Wu

  • Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

    Rui Su;Lei Dong;Yangchan Li;Min Gao

  • Leukaemogenesis: more than mutant genes

    Jianjun Chen;Olatoyosi Odenike;Janet D. Rowley

  • Over 20% of human transcripts might form sense–antisense pairs

    Jianjun Chen;Miao Sun;W. James Kent;Xiaoqiu Huang

  • MicroRNA and cancer: Current status and prospective

    Wei Wu;Miao Sun;Gang-Ming Zou;Jianjun Chen

  • IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner

    Simon Müller;Markus Glaß;Anurag K Singh;Jacob Haase

  • HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis

    Miao Sun;Chun Xiao Song;Hao Huang;Casey A. Frankenberger

  • Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization.

    Relja Popovic;Laurie E. Riesbeck;Chinavenmeni S. Velu;Aditya Chaubey

  • TET1 plays an essential oncogenic role in MLL-rearranged leukemia

    Hao Huang;Xi Jiang;Zejuan Li;Yuanyuan Li

  • Oligo(dT) primer generates a high frequency of truncated cDNAs through internal poly(A) priming during reverse transcription

    Douglas Kyung Nam;Sanggyu Lee;Guolin Zhou;Xiaohong Cao

Frequent Co-Authors

Janet D. Rowley
Janet D. Rowley University of Chicago
Richard A. Larson
Richard A. Larson University of Chicago
Chuan He
Chuan He University of Chicago
Michelle M. Le Beau
Michelle M. Le Beau University of Chicago
Jun Lu
Jun Lu Zhejiang University
Abdel G. Elkahloun
Abdel G. Elkahloun National Human Genome Research Institute
James C. Mulloy
James C. Mulloy Cincinnati Children's Hospital Medical Center
Todd R. Golub
Todd R. Golub Harvard University
Stefan K. Bohlander
Stefan K. Bohlander University of Auckland
Seungpyo Hong
Seungpyo Hong University of Wisconsin–Madison

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