World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
45
Citations
12524
World Ranking
2835
National Ranking
1358

Overview

Jens Lykke-Andersen is affiliated with the University of California, San Diego in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology as a subfield. Their scientific work covers areas such as RNA Research and Splicing, RNA modifications and cancer, RNA and protein synthesis mechanisms, Cancer-related molecular mechanisms research, CRISPR and Genetic Engineering, Advanced biosensing and bioanalysis techniques, and RNA regulation and disease.

The scientist has contributed articles to various publication venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • RNA
  • Nature Chemical Biology
  • Genes & Development
  • Molecular and Cellular Biology

Recent notable papers by Jens Lykke-Andersen include:

  • "Assigning functionality to cysteines by base editing of cancer dependency genes," published in 2023 in Nature Chemical Biology
  • "Competition between maturation and degradation drives human snRNA 3' end quality control," published in 2020 in Genes & Development
  • "The Conserved CNOT1 Interaction Motif of Tristetraprolin Regulates ARE-mRNA Decay Independently of the p38 MAPK-MK2 Kinase Pathway," published in 2022 in Molecular and Cellular Biology
  • "Cytoplasmic mRNA decay and quality control machineries in eukaryotes," expected in 2025 in Nature Reviews Genetics
  • "Sm complex assembly and 5' cap trimethylation promote selective processing of snRNAs by the 3' exonuclease TOE1," published in 2024 in Proceedings of the National Academy of Sciences

Frequent coauthors of Jens Lykke-Andersen include:

  • Timothy Shaw
  • Tiantai Ma
  • Rea M. Lardelli
  • Megan E. Dowdle
  • Alberto Carreño

Best Publications

  • Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

    Nancy Kedersha;Georg Stoecklin;Maranatha Ayodele;Patrick Yacono

  • A Family of Insulin-Like Growth Factor II mRNA-Binding Proteins Represses Translation in Late Development

    Jacob Nielsen;Jan Christiansen;Jens Lykke-Andersen;Anders H. Johnsen

  • Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon.

    Jens Lykke-Andersen;Mei-Di Shu;Joan A. Steitz

  • Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1

    Jens Lykke-Andersen;Eileen Wagner

  • Multiple Processing Body Factors and the ARE Binding Protein TTP Activate mRNA Decapping

    Martin Fenger-Grøn;Christy Fillman;Bodil Norrild;Jens Lykke-Andersen

  • The control of mRNA decapping and P-body formation.

    Tobias M. Franks;Jens Lykke-Andersen

  • Communication of the Position of Exon-Exon Junctions to the mRNA Surveillance Machinery by the Protein RNPS1

    Jens Lykke-Andersen;Mei-Di Shu;Joan A. Steitz

  • Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay.

    Jens Lykke-Andersen

  • A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay.

    Guramrit Singh;Indrani Rebbapragada;Jens Lykke-Andersen

  • Execution of nonsense-mediated mRNA decay: what defines a substrate?

    Indrani Rebbapragada;Jens Lykke-Andersen

  • TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements.

    Tobias M. Franks;Jens Lykke-Andersen

  • mRNA surveillance: the perfect persist

    Eileen Wagner;Jens Lykke-Andersen

  • A human microprotein that interacts with the mRNA decapping complex

    Nadia G D'Lima;Jiao Ma;Lauren Winkler;Qian Chu

  • Translational coregulation of 5′TOP mRNAs by TIA-1 and TIAR

    Christian Kroun Damgaard;Jens Lykke-Andersen

  • Upf1 ATPase-Dependent mRNP Disassembly Is Required for Completion of Nonsense- Mediated mRNA Decay

    Tobias M. Franks;Tobias M. Franks;Guramrit Singh;Jens Lykke-Andersen;Jens Lykke-Andersen

  • Phosphorylation of Tristetraprolin by MK2 Impairs AU-Rich Element mRNA Decay by Preventing Deadenylase Recruitment

    Sandra L. Clement;Claudia Scheckel;Claudia Scheckel;Georg Stoecklin;Jens Lykke-Andersen;Jens Lykke-Andersen

  • mRNA decapping factors and the exonuclease Xrn2 function in widespread premature termination of RNA polymerase II transcription

    Kris Brannan;Hyunmin Kim;Benjamin Erickson;Kira Glover-Cutter

  • H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein.

    Steffen Runge;Finn Cilius Nielsen;Jacob Nielsen;Jens Lykke-Andersen

  • Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay

    Melissa A Hausburg;Jason D Doles;Sandra L Clement;Adam B Cadwallader

  • Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System

    Fernando J. Martinez;Gabriel A. Pratt;Eric L. Van Nostrand;Ranjan Batra

Frequent Co-Authors

Roger A. Garrett
Roger A. Garrett University of Copenhagen
Gene W. Yeo
Gene W. Yeo University of California, San Diego
Perry J. Blackshear
Perry J. Blackshear National Institutes of Health
Finn Cilius Nielsen
Finn Cilius Nielsen Copenhagen University Hospital
Georg Stoecklin
Georg Stoecklin Heidelberg University
Randal J. Kaufman
Randal J. Kaufman Sanford Burnham Prebys Medical Discovery Institute
Ulla M. Wewer
Ulla M. Wewer University of Copenhagen
Joan A. Steitz
Joan A. Steitz Yale University
Hirotomo Saitsu
Hirotomo Saitsu Hamamatsu University
Joseph G. Gleeson
Joseph G. Gleeson University of California, San Diego

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a degree in Molecular Biology can open doors to a wide range of related online programs and diverse career pathways. Many students choose to complement their science background with specialized skills in areas like social work, psychology, or counseling. Exploring programs such as msw online programs can prepare graduates for impactful roles in healthcare and community support services.

For those interested in mental health or therapies, options like accelerated psychology masters programs or an online masters degree in mental health counseling provide flexible and fast-tracked routes to advanced credentials. These programs are ideal for students aiming to bridge science education with the human aspects of wellness and behavior.

Additionally, there are military friendly colleges offering online degrees in these fields, making it possible for military members and veterans to further their studies while balancing service commitments. Each of these online pathways offers unique advantages for students looking to build multidisciplinary expertise and pursue rewarding careers.

Best Scientists Citing Jens Lykke-Andersen

Trending Scientists