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Microbiology

D-Index
46
Citations
11575
World Ranking
4854
National Ranking
333

Overview

Heiko Jessen is affiliated with the University Hospital Bonn in Germany and has contributed extensively to the field of medicine, with a particular focus on infectious diseases. Their research portfolio spans 33 publications mainly in medicine, including subfields such as infectious diseases, emergency medicine, epidemiology, virology, and hepatology.

The main topics of Heiko Jessen's work center on HIV/AIDS research and interventions, HIV/AIDS drug development and treatment, and HIV-related health complications and treatments. Additional research interests include aspects of drug use and sexual risk in relation to HIV, HIV research and treatment broadly, sex work and related issues, and hepatitis C virus research.

Heiko Jessen's publication record includes multiple articles appearing in notable journals. Frequent publication venues are:

  • BMC Infectious Diseases
  • Journal of Antimicrobial Chemotherapy
  • The Lancet
  • The Lancet HIV
  • BMC Public Health

Among recent papers, the following represent key contributions:

  • Emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): primary results from a randomised, double-blind, multicentre, active-controlled, phase 3, non-inferiority trial (2020), published in The Lancet
  • STI in times of PrEP: high prevalence of chlamydia, gonorrhea, and mycoplasma at different anatomic sites in men who have sex with men in Germany (2020), published in BMC Infectious Diseases
  • Long-term safety and efficacy of emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV-1 pre-exposure prophylaxis: week 96 results from a randomised, double-blind, placebo-controlled, phase 3 trial (2021), published in The Lancet HIV
  • Barriers to using HIV pre-exposure prophylaxis (PrEP) and sexual behaviour after stopping PrEP: a cross-sectional study in Germany (2021), published in BMC Public Health
  • Efficacy and Safety of Switching to Dolutegravir With Boosted Darunavir in Virologically Suppressed Adults With HIV-1: A Randomized, Open-Label, Multicenter, Phase 3, Noninferiority Trial: The DUALIS Study (2020), published in Open Forum Infectious Diseases

Heiko Jessen has also collaborated regularly with several frequent co-authors, including:

  • Christoph D. Spinner
  • Christiane Cordes
  • Stefan Scholten
  • Petra Spornraft-Ragaller
  • Björn-Erik Ole Jensen

Best Publications

  • Efficacy of Quadrivalent HPV Vaccine against HPV Infection and Disease in Males

    Anna R. Giuliano;Joel M. Palefsky;Stephen Goldstone;Edson D. Moreira

  • HPV Vaccine against Anal HPV Infection and Anal Intraepithelial Neoplasia

    Joel M. Palefsky;Anna R. Giuliano;Stephen Goldstone;Edson D. Moreira

  • Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study

    Alison J Rodger;Valentina Cambiano;Tina Bruun;Pietro Vernazza

  • Emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): primary results from a randomised, double-blind, multicentre, active-controlled, phase 3, non-inferiority trial.

    Kenneth H Mayer;Kenneth H Mayer;Jean-Michel Molina;Melanie A Thompson;Peter L Anderson

  • Control of HIV despite the discontinuation of antiretroviral therapy.

    Julianna Lisziewicz;Eric Rosenberg;Judy Lieberman;Heiko Jessen

  • Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection

    Matthew R. Henn;Christian L. Boutwell;Patrick Charlebois;Niall J Lennon

  • HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1

    Marcus Altfeld;Elizabeth T Kalife;Ying Qi;Hendrik Streeck

  • Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution

    Todd M. Allen;Marcus Altfeld;Shaun C. Geer;Elizabeth T. Kalife

  • HIV-Specific Cytolytic CD4 T Cell Responses During Acute HIV Infection Predict Disease Outcome

    Damien Z. Soghoian;Heiko Jessen;Michael Flanders;Kailan Sierra-Davidson

  • IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells.

    Mark A. Brockman;Mark A. Brockman;Douglas S. Kwon;Douglas S. Kwon;Douglas S. Kwon;Daniel P. Tighe;David F. Pavlik

  • HIV pre-exposure prophylaxis (PrEP): a review of current knowledge of oral systemic HIV PrEP in humans

    Christoph D. Spinner;Christoph Boesecke;Alexander Zink;Heiko Jessen

  • Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4+ T Cells

    Hendrik Streeck;Jonathan S. Jolin;Ying Qi;Bader Yassine-Diab

  • Prevalence of and Risk Factors for Human Papillomavirus (HPV) Infection Among HIV-Seronegative Men Who Have Sex With Men

    Stephen Goldstone;Joel M. Palefsky;Anna R. Giuliano;Edson D. Moreira

  • HIV-1-Specific Interleukin-21+ CD4+ T Cell Responses Contribute to Durable Viral Control through the Modulation of HIV-Specific CD8+ T Cell Function

    Mathieu F. Chevalier;Boris Jülg;Augustine Pyo;Michael Flanders

  • Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection

    Zabrina L. Brumme;Chanson J. Brumme;Jonathan Carlson;Jonathan Carlson;Hendrik Streeck

  • Detection of minor populations of drug-resistant HIV-1 in acute seroconverters.

    Karin J Metzner;Pia Rauch;Hauke Walter;Christoph Boesecke

  • STI in times of PrEP: high prevalence of chlamydia, gonorrhea, and mycoplasma at different anatomic sites in men who have sex with men in Germany

    Klaus Jansen;Gyde Steffen;Gyde Steffen;Anja Potthoff;Ann-Kathrin Schuppe

  • Early Selection in Gag by Protective HLA Alleles Contributes to Reduced HIV-1 Replication Capacity That May Be Largely Compensated for in Chronic Infection

    Mark A. Brockman;Mark A. Brockman;Mark A. Brockman;Zabrina L. Brumme;Zabrina L. Brumme;Zabrina L. Brumme;Chanson J. Brumme;Chanson J. Brumme;Toshiyuki Miura;Toshiyuki Miura

  • A Functional Toll-Like Receptor 8 Variant Is Associated with HIV Disease Restriction

    D.-Y. Oh;S. Taube;S. Taube;O. Hamouda;C. Kücherer

  • Impaired Replication Capacity of Acute/Early Viruses in Persons Who Become HIV Controllers

    Toshiyuki Miura;Zabrina L. Brumme;Mark A. Brockman;Pamela Rosato

  • Efficacy and safety of efavirenz 400 mg daily versus 600 mg daily: 96-week data from the randomised, double-blind, placebo-controlled, non-inferiority ENCORE1 study

    Dianne Carey;Rebekah Puls;Janaki Amin

  • Immunogenicity of the Quadrivalent Human Papillomavirus (Type 6/11/16/18) Vaccine in Males 16 to 26 Years Old

    Richard J. Hillman;Anna R. Giuliano;Joel M. Palefsky;Stephen Goldstone

  • A frequent functional toll-like receptor 7 polymorphism is associated with accelerated HIV-1 disease progression.

    Djin-Ye Oh;Konstantin Baumann;Osamah Hamouda;Jana K Eckert

Frequent Co-Authors

Bruce D. Walker
Bruce D. Walker Harvard University
Zabrina L. Brumme
Zabrina L. Brumme Simon Fraser University
Eric S. Rosenberg
Eric S. Rosenberg Harvard University
Todd M. Allen
Todd M. Allen Harvard University
Mark A. Brockman
Mark A. Brockman Simon Fraser University
Anthony D. Kelleher
Anthony D. Kelleher University of New South Wales
Chanson J. Brumme
Chanson J. Brumme University of British Columbia
Marcus Altfeld
Marcus Altfeld University Medical Center Hamburg-Eppendorf
Hendrik Streeck
Hendrik Streeck University Hospital Bonn
Martin Markowitz
Martin Markowitz Rockefeller University

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